Rapid and Selective Access to Three Distinct Sets of Indole-Based Heterocycles From a Single Set of Ugi-Adducts Under Microwave Heating.
Rapid and selective access to three distinct sets of indole-based heterocycles from a single set of Ugi-adducts under microwave heating.
Chem Commun (Camb). 2013 Mar 1;
Zhang L, Zhao F, Zheng M, Zhai Y, Liu H
Three distinct sets… Continue reading
Human Concentrative Nucleoside Transporter 3 Transfection With Ultrasound and Microbubbles in Nucleoside Transport Deficient HEK293 Cells Greatly Increases Gemcitabine Uptake.
Human Concentrative Nucleoside Transporter 3 Transfection with Ultrasound and Microbubbles in Nucleoside Transport Deficient HEK293 Cells Greatly Increases Gemcitabine Uptake.
PLoS One. 2013; 8(2): e56423
Paproski RJ, Yao SY, Favis N, Evans D, Young JD, Cass CE, Zemp RJ… Continue reading
Computational Analysis of siRNA Recognition by the Ago2 PAZ Domain and Identification of the Determinants of RNA-Induced Gene Silencing.
Computational Analysis of siRNA Recognition by the Ago2 PAZ Domain and Identification of the Determinants of RNA-Induced Gene Silencing.
PLoS One. 2013; 8(2): e57140
Kandeel M, Kitade Y
RNA interference (RNAi) is a highly specialized process of protein-siRNA interaction… Continue reading
Nucleus Accumbens Deep Brain Stimulation Results in Insula and Prefrontal Activation: A Large Animal FMRI Study.
Nucleus accumbens deep brain stimulation results in insula and prefrontal activation: a large animal FMRI study.
PLoS One. 2013; 8(2): e56640
Knight EJ, Min HK, Hwang SC, Marsh MP, Paek S, Kim I, Felmlee JP, Abulseoud OA, Bennet KE,… Continue reading
Transcriptional Profiles of the Response of Methicillin-Resistant Staphylococcus Aureus to Pentacyclic Triterpenoids.
Transcriptional Profiles of the Response of Methicillin-Resistant Staphylococcus aureus to Pentacyclic Triterpenoids.
PLoS One. 2013; 8(2): e56687
Chung PY, Chung LY, Navaratnam P
Staphylococcus aureus is an important human pathogen in both hospital and the community that has demonstrated… Continue reading
Gene Expression and Thiopurine Metabolite Profiling in Inflammatory Bowel Disease – Novel Clues to Drug Targets and Disease Mechanisms?
Gene expression and thiopurine metabolite profiling in inflammatory bowel disease – novel clues to drug targets and disease mechanisms?
PLoS One. 2013; 8(2): e56989
Haglund S, Almer S, Peterson C, Söderman J
Thiopurines are effective to induce and maintain remission in inflammatory bowel disease (IBD). The methyl thioinosine monophosphate (meTIMP)/6-thioguanine nucleotide (6-TGN) concentration ratio has been associated with drug efficacy. Here we explored the molecular basis of differences in metabolite profiles and in relation to disease activity.Transcriptional profiles in blood samples from an exploratory IBD-patient cohort (n?=?21) with a normal thiopurine S-methyltransferase phenotype and meTIMP/6-TGN ratios >20, 10.0-14.0 and ?4, respectively, were assessed… Continue reading