oral bioavailability

Multidrug-Resistant Tuberculosis in Panama Is Driven by Clonal Expansion of an MDR-TB Strain Related to the KZN XDR-TB Strain From South Africa.

Multidrug-resistant tuberculosis in Panama is driven by clonal expansion of an MDR-TB strain related to the KZN XDR-TB strain from South Africa.

J Clin Microbiol. 2013 Jul 24;
Lanzas F, Karakousis PC, Sacchettini JC, Ioerger TR

Multidrug-resistant tuberculosis (MDR-TB)… Continue reading

Nanotechnology in the Targeted Drug Delivery for Bone Diseases and Bone Regeneration.

Nanotechnology in the targeted drug delivery for bone diseases and bone regeneration.

Int J Nanomedicine. 2013; 8: 2305-17
Gu W, Wu C, Chen J, Xiao Y

Nanotechnology is a vigorous research area and one of its important applications is… Continue reading

Influences of the Aging Process on Acute Perioperative Pain Management in Elderly and Cognitively Impaired Patients.

Influences of the Aging Process on Acute Perioperative Pain Management in Elderly and Cognitively Impaired Patients.

Ochsner J. 2013; 13(2): 228-247
Halaszynski T

The aging process results in physiological deterioration and compromise along with a reduction in the reserve… Continue reading

Use of Bayesian Statistics in Drug Development: Advantages and Challenges.

Use of Bayesian statistics in drug development: Advantages and challenges.

Int J Appl Basic Med Res. 2012 Jan; 2(1): 3-6
Gupta SK

MAINLY, TWO STATISTICAL METHODOLOGIES ARE APPLICABLE TO THE DESIGN AND ANALYSIS OF CLINICAL TRIALS: frequentist and Bayesian.… Continue reading

Prodrug Design, Synthesis and Pharmacokinetic Evaluation of (3′ R, 4′ R)-3-Hydroxymethyl-4-Methyl-3′,4′-Di-O-(S)-Camphanoyl-(+)-Cis-Khellactone.

Prodrug design, synthesis and pharmacokinetic evaluation of (3′ R, 4′ R)-3-hydroxymethyl-4-methyl-3′,4′-di-O-(S)-camphanoyl-(+)-cis-khellactone.

Acta Pharm Sin B. 2012 Apr 1; 2(2): 213-219
Guo H, Zhuang X, Qian K, Sun L, Wang X, Li H, Lee K, Xie L

3-Hydroxymethyl-4-methyl-DCK (3, HMDCK)… Continue reading

Influence of Excipients and Processing Conditions on the Development of Agglomerates of Racecadotril by Crystallo-Co-Agglomeration.

Influence of excipients and processing conditions on the development of agglomerates of racecadotril by crystallo-co-agglomeration.

Int J Pharm Investig. 2012 Oct; 2(4): 189-200
Garala K, Patel J, Patel A, Raval M, Dharamsi A

The purpose of the present investigation… Continue reading

Effective Concentration-Based Serum Pharmacodynamics for Antifungal Azoles in a Murine Model of Disseminated Candida Albicans Infection.

Effective concentration-based serum pharmacodynamics for antifungal azoles in a murine model of disseminated Candida albicans infection.

Eur J Drug Metab Pharmacokinet. 2013 Mar 29;
Maki K, Kaneko S

An assessment of the effective in vivo concentrations of antifungal drugs… Continue reading

Comparative Performance of Two Drug Interaction Screening Programmes Analysing a Cross-Sectional Prescription Dataset of 84,625 Psychiatric Inpatients.

Comparative Performance of Two Drug Interaction Screening Programmes Analysing a Cross-Sectional Prescription Dataset of 84,625 Psychiatric Inpatients.

Drug Saf. 2013 Mar 14;
Zorina OI, Haueis P, Greil W, Grohmann R, Kullak-Ublick GA, Russmann S

BACKGROUND: Clinical decision support software… Continue reading

[Research Progress of Self-Assembled Beads Drug Delivery System Prepared From Cyclodextrins and Oils].

[Research progress of self-assembled beads drug delivery system prepared from cyclodextrins and oils].

Yao Xue Xue Bao. 2012 Dec; 47(12): 1582-6
Liu C, Yi T

Recently, increasing attention has been paid to beads, an innovative self-assembled drug delivery system… Continue reading

iADRs: Towards Online Adverse Drug Reaction Analysis.

iADRs: towards online adverse drug reaction analysis.

Filed under: Drug and Alcohol Rehabilitation

Springerplus. 2012 Dec; 1(1): 72
Lin WY, Li HY, Du JW, Feng WY, Lo CF, Soo VW

Adverse Drug Reaction (ADR) is one of the most… Continue reading