opioid receptor

Kappa-Opioid Receptor Signaling in the Striatum as a Potential Modulator of Dopamine Transmission in Cocaine Dependence.

Kappa-opioid receptor signaling in the striatum as a potential modulator of dopamine transmission in cocaine dependence.

Front Psychiatry. 2013; 4: 44
Trifilieff P, Martinez D

Cocaine addiction is accompanied by a decrease in striatal dopamine signaling, measured as a… Continue reading

Cocaine Tolerance in Honey Bees.

Cocaine tolerance in honey bees.

PLoS One. 2013; 8(5): e64920
Søvik E, Cornish JL, Barron AB

Increasingly invertebrates are being used to investigate the molecular and cellular effects of drugs of abuse to explore basic mechanisms of addiction. However,… Continue reading

Is “Loss of Control” Always a Consequence of Addiction?

Is “Loss of Control” Always a Consequence of Addiction?

Front Psychiatry. 2013; 4: 36
Griffiths MD

HubMed – addiction

 

Stress differentially alters mu opioid receptor density and trafficking in parvalbumin-containing interneurons in the female and male rat hippocampus.… Continue reading

MicroRNAs and Drug Addiction.

MicroRNAs and Drug Addiction.

Front Genet. 2013; 4: 43
Bali P, Kenny PJ

Drug addiction is considered a disorder of neuroplasticity in brain reward and cognition systems resulting from aberrant activation of gene expression programs in response to prolonged… Continue reading

ELK1 Transcription Factor Linked to Dysregulated Striatal Mu Opioid Receptor Signaling Network and OPRM1 Polymorphism in Human Heroin Abusers.

ELK1 Transcription Factor Linked to Dysregulated Striatal Mu Opioid Receptor Signaling Network and OPRM1 Polymorphism in Human Heroin Abusers.

Biol Psychiatry. 2013 May 20;
Sillivan SE, Whittard JD, Jacobs MM, Ren Y, Mazloom AR, Caputi FF, Horvath M, Keller… Continue reading

Neural Effects of Positive and Negative Incentives During Marijuana Withdrawal.

Neural Effects of Positive and Negative Incentives during Marijuana Withdrawal.

PLoS One. 2013; 8(5): e61470
Filbey FM, Dunlop J, Myers US

In spite of evidence suggesting two possible mechanisms related to drug-seeking behavior, namely reward-seeking and harm avoidance, much… Continue reading

A Bivalent Ligand Targeting the Putative Mu Opioid Receptor and Chemokine Receptor CCR5 Heterodimers: Binding Affinity Versus Functional Activities.

A Bivalent Ligand Targeting the Putative Mu Opioid Receptor and Chemokine Receptor CCR5 Heterodimers: Binding Affinity versus Functional Activities.

Medchemcomm. 2013 May 1; 4(5): 847-851
Yuan Y, Arnatt CK, El-Hage N, Dever SM, Jacob JC, Selley DE, Hauser KF,… Continue reading

Psychometric Properties of the Internet Addiction Test in Chinese Adolescents.

Psychometric Properties of the Internet Addiction Test in Chinese Adolescents.

J Pediatr Psychol. 2013 May 13;
Lai CM, Mak KK, Watanabe H, Ang RP, Pang JS, Ho RC

OBJECTIVE: This study examined the psychometric properties of the Young’s Internet… Continue reading

Comparison of Responses of Human Melanoma Cell Lines to MEK and BRAF Inhibitors.

Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.

Front Genet. 2013; 4: 66
Stones CJ, Kim JE, Joseph WR, Leung E, Marshall ES, Finlay GJ, Shelling AN, Baguley BC

The NRAS and BRAF genes… Continue reading

OPRM1 Rs1799971 Polymorphism and Opioid Dependence: Evidence From a Meta-Analysis.

OPRM1 rs1799971 polymorphism and opioid dependence: evidence from a meta-analysis.

Pharmacogenomics. 2013 May; 14(7): 813-24
Haerian BS, Haerian MS

The OPRM1 gene encodes the µ-opioid receptor, which is the primary site of action of most opioids. Several studies and… Continue reading