Molecular mechanisms

Depression Treatment: Vesicular Signalling and Immune Modulation as Hedonic Fingerprints: Proteomic Profiling in the Chronic Mild Stress Depression Model.

Vesicular signalling and immune modulation as hedonic fingerprints: proteomic profiling in the chronic mild stress depression model.

Filed under: Depression Treatment

J Psychopharmacol. 2012 Nov 8;
Bisgaard CF, Bak S, Christensen T, Jensen ON, Enghild JJ, Wiborg O

Extensive… Continue reading

Epigenetics-Beyond the Genome in Alcoholism.

Epigenetics-beyond the genome in alcoholism.

Filed under: Addiction Rehab

Alcohol Res. 2012; 34(3): 293-305
Starkman BG, Sakharkar AJ, Pandey SC

Genetic and environmental factors play a role in the development of alcoholism. Whole-genome expression profiling has highlighted the importance… Continue reading

Addiction Rehab: Alcohol Intoxication in the Context of Major Public Holidays, Sporting and Social Events: A Time-Series Analysis in Melbourne, Australia, 2000-2009.

Alcohol intoxication in the context of major public holidays, sporting and social events: A time-series analysis in Melbourne, Australia, 2000-2009.

Filed under: Addiction Rehab

Addiction. 2012 Nov 8;
Lloyd B, Matthews S, Livingston M, Jayasekara H, Smith K

AIMS:… Continue reading

Drug and Alcohol Rehabilitation: Gatifloxacin Induces S and G(2)-Phase Cell Cycle Arrest in Pancreatic Cancer Cells via P21/p27/p53.

Gatifloxacin Induces S and G(2)-Phase Cell Cycle Arrest in Pancreatic Cancer Cells via p21/p27/p53.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2012; 7(10): e47796
Yadav V, Sultana S, Yadav J, Saini N

Pancreatic cancer, despite being the most… Continue reading

A Divalent Ion Is Crucial in the Structure and Dominant-Negative Function of ID Proteins, a Class of Helix-Loop-Helix Transcription Regulators.

A Divalent Ion Is Crucial in the Structure and Dominant-Negative Function of ID Proteins, a Class of Helix-Loop-Helix Transcription Regulators.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2012; 7(10): e48591
Wong MV, Jiang S, Palasingam P, Kolatkar PR… Continue reading

Depression Treatment: Clinical Patterns and Treatment Outcome in Patients With Melancholic, Atypical and Non-Melancholic Depressions.

Clinical patterns and treatment outcome in patients with melancholic, atypical and non-melancholic depressions.

Filed under: Depression Treatment

PLoS One. 2012; 7(10): e48200
Gili M, Roca M, Armengol S, Asensio D, Garcia-Campayo J, Parker G

To assess sociodemographic, clinical and… Continue reading

Reprofiling a Classical Anthelmintic, Pyrvinium Pamoate, as an Anti-Cancer Drug Targeting Mitochondrial Respiration.

Reprofiling a classical anthelmintic, pyrvinium pamoate, as an anti-cancer drug targeting mitochondrial respiration.

Filed under: Drug and Alcohol Rehabilitation

Front Oncol. 2012; 2: 137
Ishii I, Harada Y, Kasahara T

Pyrvinium pamoate (PP) is an FDA-approved classical anthelmintic, but… Continue reading

Autophagy: A Novel Therapeutic Target for Kidney Diseases.

Autophagy: a novel therapeutic target for kidney diseases.

Filed under: Eating Disorders

Clin Exp Nephrol. 2012 Sep 13;
Kume S, Uzu T, Maegawa H, Koya D

Autophagy meaning ‘self-eating’ in Greek, is a large-scale mechanism of intracellular degradation that… Continue reading

Addiction Rehab: [Fatty Acids of Grape Seed Oil and Its Biological Activity as 1,0% and 2,5% Food-Additive;].

[Fatty acids of grape seed oil and its biological activity as 1,0% and 2,5% food-additive;].

Filed under: Addiction Rehab

Georgian Med News. 2012 Jun; 47-50
Kikalishvili B, Zurabashvili D, Turabelidze D, Zurabashvili Z, Giorgobiani I

Using high-performance liquid chromatography… Continue reading

Molecular Mechanisms Involved in Depotentiation and Their Relevance to Schizophrenia.

Molecular mechanisms involved in depotentiation and their relevance to schizophrenia.

Filed under: Depression Treatment

Chonnam Med J. 2012 Apr; 48(1): 1-6
Sanderson TM

Long-term potentiation (LTP) and long-term depression (LTD) of synaptic transmission are forms of synaptic plasticity that… Continue reading