molecular mechanism

Proteomic Approach Toward Molecular Backgrounds of Drug Resistance of Osteosarcoma Cells in Spheroid Culture System.

Proteomic approach toward molecular backgrounds of drug resistance of osteosarcoma cells in spheroid culture system.

Proteomics. 2013 May 28;
Arai K, Sakamoto R, Kubota D, Kondo T

Chemoresistance is one of the most critical prognostic factors in osteosarcoma, and… Continue reading

Visual Outcome of Cataract in Pediatric Age Group: Does Etiology Have a Role.

Visual outcome of cataract in pediatric age group: does etiology have a role.

Eur J Ophthalmol. 2013 May 13; 0
Shah MA, Shah SM, Shah AH, Pandya JS

Objective: To compare visual outcome results among traumatic and nontraumatic groups… Continue reading

Epigenetic Mechanisms Shape the Biological Response to Trauma and Risk for PTSD: A Critical Review.

Epigenetic Mechanisms Shape the Biological Response to Trauma and Risk for PTSD: A Critical Review.

Nurs Res Pract. 2013; 2013: 417010
Heinzelmann M, Gill J

Posttraumatic stress disorder (PTSD) develops in approximately one-quarter of trauma-exposed individuals, leading us and… Continue reading

Rapid Countermeasure Discovery Against Francisella Tularensis Based on a Metabolic Network Reconstruction.

Rapid Countermeasure Discovery against Francisella tularensis Based on a Metabolic Network Reconstruction.

PLoS One. 2013; 8(5): e63369
Chaudhury S, Abdulhameed MD, Singh N, Tawa GJ, D’haeseleer PM, Zemla AT, Navid A, Zhou CE, Franklin MC, Cheung J, Rudolph MJ,… Continue reading

ELK1 Transcription Factor Linked to Dysregulated Striatal Mu Opioid Receptor Signaling Network and OPRM1 Polymorphism in Human Heroin Abusers.

ELK1 Transcription Factor Linked to Dysregulated Striatal Mu Opioid Receptor Signaling Network and OPRM1 Polymorphism in Human Heroin Abusers.

Biol Psychiatry. 2013 May 20;
Sillivan SE, Whittard JD, Jacobs MM, Ren Y, Mazloom AR, Caputi FF, Horvath M, Keller… Continue reading

Genetic Distribution and Association Analysis of DRD2 Gene Polymorphisms With Major Depressive Disorder in the Chinese Han Population.

Genetic distribution and association analysis of DRD2 gene polymorphisms with major depressive disorder in the Chinese Han population.

Int J Clin Exp Pathol. 2013; 6(6): 1142-9
He M, Yan H, Duan ZX, Qu W, Gong HY, Fan ZL, Kang… Continue reading

BDNF Over-Expression in the Ventral Tegmental Area Prolongs Social Defeat Stress-Induced Cross-Sensitization to Amphetamine and Increases ?FosB Expression in Mesocorticolimbic Regions of Rats.

BDNF Over-Expression in the Ventral Tegmental Area Prolongs Social Defeat Stress-induced Cross-Sensitization to Amphetamine and Increases ?FosB Expression in Mesocorticolimbic Regions of Rats.

Neuropsychopharmacology. 2013 May 21;
Wang J, Fanous S, Terwilliger EF, Bass CE, Hammer RP, Nikulina EM… Continue reading

Major Channels Involved in Neuropsychiatric Disorders and Therapeutic Perspectives.

Major channels involved in neuropsychiatric disorders and therapeutic perspectives.

Front Genet. 2013; 4: 76
Imbrici P, Camerino DC, Tricarico D

Voltage-gated ion channels are important mediators of physiological functions in the central nervous system. The cyclic activation of these… Continue reading

Mitochondrial Dysfunction, Oxidative Stress, and Major Depressive Disorder.

Mitochondrial dysfunction, oxidative stress, and major depressive disorder.

Neuropsychiatr Dis Treat. 2013; 9: 567-73
Tobe EH

There is controversy about depression being a physical illness, in part because a reproducible, sensitive, and specific biologic marker is not available. However,… Continue reading

Regulation Where Autophagy Intersects the Inflammasome.

Regulation where autophagy intersects the inflammasome.

Antioxid Redox Signal. 2013 May 5;
Rodgers MA, Bowman JW, Liang Q, Jung JU

Significance: The autophagy and inflammasome pathways are ancient innate immune mechanisms for controlling invading pathogens that are linked by… Continue reading