model systems

Perioperative Morbidity and Mortality of Same-Day Bilateral TKAs: Incidence and Risk Factors.

Perioperative Morbidity and Mortality of Same-day Bilateral TKAs: Incidence and Risk Factors.

Clin Orthop Relat Res. 2013 Jul 9;
Poultsides L, Memtsoudis S, Gonzalez Della Valle A, De Martino I, Do HT, Alexiades M, Sculco T

Controversy persists regarding… Continue reading

Specialized Early Treatment for Persons With Disorders of Consciousness: Program Components and Outcomes.

Specialized Early Treatment for Persons with Disorders of Consciousness: Program Components and Outcomes.

Arch Phys Med Rehabil. 2013 May 31;
Seel RT, Douglas J, Dennison AC, Heaner S, Farris K, Rogers C

OBJECTIVE: To describe a specialized early treatment… Continue reading

Factors Associated With Sexuality Following Traumatic Brain Injury.

Factors associated with sexuality following traumatic brain injury.

J Head Trauma Rehabil. 2013 May-Jun; 28(3): 195-201
Ponsford JL, Downing MG, Stolwyk R

: Previous research has demonstrated that sexuality is compromised following traumatic brain injury (TBI).: The aim of… Continue reading

Backbone and ILV Methyl Resonance Assignments of E. Coli Thymidylate Synthase Bound to Cofactor and a Nucleotide Analogue.

Backbone and ILV methyl resonance assignments of E. coli thymidylate synthase bound to cofactor and a nucleotide analogue.

Biomol NMR Assign. 2013 May 9;
Sapienza PJ, Lee AL

Thymidylate synthase (TSase) is a 62 kDa homodimeric enzyme required… Continue reading

In Vitro Model Systems to Study Androgen Receptor Signaling in Prostate Cancer.

In vitro model systems to study androgen receptor signaling in prostate cancer.

Endocr Relat Cancer. 2013 Apr; 20(2): R49-64
Sampson N, Neuwirt H, Puhr M, Klocker H, Eder IE

Prostate cancer (PCa) is one of the most common causes… Continue reading

Anti-Inflammatory Dimethylfumarate: A Potential New Therapy for Asthma?

Anti-inflammatory dimethylfumarate: a potential new therapy for asthma?

Mediators Inflamm. 2013; 2013: 875403
Seidel P, Roth M

Asthma is a chronic inflammatory disease of the airways, which results from the deregulated interaction of inflammatory cells and tissue forming cells.… Continue reading

An Orexin Hotspot in Ventral Pallidum Amplifies Hedonic ‘liking’ for Sweetness.

An orexin hotspot in ventral pallidum amplifies hedonic ‘liking’ for sweetness.

Neuropsychopharmacology. 2013 Mar 5;
Ho CY, Berridge KC

Orexin (hypocretin) is implicated in stimulating appetite as well as arousal, and in both food reward and drug reward. The… Continue reading

A Review of the Evidence Regarding Associations Between Attachment Theory and Experimentally Induced Pain.

A review of the evidence regarding associations between attachment theory and experimentally induced pain.

Curr Pain Headache Rep. 2013 Apr; 17(4): 326
Meredith PJ

Theoretical and empirical evidence suggests that adult attachment and pain-related variables are predictably and consistently… Continue reading

Kinetic Modeling-Based Detection of Genetic Signatures That Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network.

Kinetic Modeling-Based Detection of Genetic Signatures that Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network.

Cancer Res. 2013 Feb 27;
Vera J, Schmitz U, Lai X, Engelmann D, Khan FM, Wolkenhauer O, Putzer BM

Drug resistance is a major cause of… Continue reading

Drug and Alcohol Rehabilitation: Protein-Chemical Interaction Prediction via Kernelized Sparse Learning Svm.

Protein-chemical interaction prediction via kernelized sparse learning svm.

Filed under: Drug and Alcohol Rehabilitation

Pac Symp Biocomput. 2013; 41-52
Shi Y, Zhang X, Liao X, Lin G, Schuurmans D

Given the difficulty of experimental determination of drug-protein interactions, there… Continue reading