memory deficits

SAHA Enhances Synaptic Function and Plasticity in Vitro but Has Limited Brain Availability in Vivo and Does Not Impact Cognition.

SAHA Enhances Synaptic Function and Plasticity In Vitro but Has Limited Brain Availability In Vivo and Does Not Impact Cognition.

PLoS One. 2013; 8(7): e69964
Hanson JE, La H, Plise E, Chen YH, Ding X, Hanania T, Sabath EV,… Continue reading

A Nine-Year Follow-Up Study of Sleep Patterns and Mortality in Community-Dwelling Older Adults in Taiwan.

A Nine-Year Follow-up Study of Sleep Patterns and Mortality in Community-Dwelling Older Adults in Taiwan.

Sleep. 2013; 36(8): 1187-98
Chen HC, Su TP, Chou P

To simultaneously explore the associations between mortality and insomnia, sleep duration, and the use of hypnotics in older adults.A fixed cohort study.A community in Shih-Pai area, Taipei, Taiwan.A total of 4,064 participants over the age of 65 completed the study.N/A.Insomnia was classified using an exclusionary hierarchical algorithm, which categorized insomnia as “no insomnia,” “subjective poor sleep quality,” “Pittsburgh Sleep Quality Index > 5 insomnia,” “1-month insomnia disorder,” and “6-month insomnia disorder.” The main outcome variables were 9-year all-cause mortality rates. In the all-cause mortality analyses, when hypnotic use, depressive symptoms and total sleep time were excluded from a proportional hazards regression model, subjects with “Pittsburgh Sleep Quality Index > 5 insomnia” had a higher mortality risk (HR: 1.21, 95% CI: 1.01-1.45). In the full model, frequent hypnotic use and long sleep duration predicted higher mortality rates. However, the increased mortality risk for subjects with “Pittsburgh Sleep Quality Index > 5 insomnia” was not observed in the full model. On the contrary, individuals with… Continue reading

Zinc Homeostasis and Neurodegenerative Disorders.

Zinc homeostasis and neurodegenerative disorders.

Front Aging Neurosci. 2013; 5: 33
Szewczyk B

Zinc is an essential trace element, whose importance to the function of the central nervous system (CNS) is increasingly being appreciated. Alterations in zinc dyshomeostasis has… Continue reading

Metabotropic Glutamate Receptor 5 Within Nucleus Accumbens Shell Modulates Environment-Elicited Cocaine Conditioning Expression.

Metabotropic Glutamate Receptor 5 within Nucleus Accumbens Shell modulates environment-elicited cocaine conditioning expression.

Pharmacol Biochem Behav. 2013 Jul 9;
Martínez-Rivera A, Rodríguez-Borrero E, Matías-Alemán M, Montalvo-Acevedo A, Guerrero-Figuereo K, Febo-Rodriguez LJ, Morales-Rivera A, Maldonado-Vlaar CS

The metabotropic glutamate receptors… Continue reading

Rationale, Timeline, Study Design, and Protocol Overview of the Therapeutic Hypothermia After Pediatric Cardiac Arrest Trials.

Rationale, Timeline, Study Design, and Protocol Overview of the Therapeutic Hypothermia After Pediatric Cardiac Arrest Trials.

Pediatr Crit Care Med. 2013 Jul 9;
Moler FW, Silverstein FS, Meert KL, Clark AE, Holubkov R, Browning B, Slomine BS, Christensen JR,… Continue reading

Association of Abstinence-Induced Alterations in Working Memory Function and COMT Genotype in Smokers.

Association of abstinence-induced alterations in working memory function and COMT genotype in smokers.

Psychopharmacology (Berl). 2013 Jul 5;
Ashare RL, Valdez JN, Ruparel K, Albelda B, Hopson RD, Keefe JR, Loughead J, Lerman C

The common methionine (met) for… Continue reading

Spatial Working Memory Deficits Represent a Core Challenge for Rehabilitating Neglect.

Spatial working memory deficits represent a core challenge for rehabilitating neglect.

Front Hum Neurosci. 2013; 7: 334
Striemer CL, Ferber S, Danckert J

Left neglect following right hemisphere injury is a debilitating disorder that has proven extremely difficult to… Continue reading

A Cross-Cultural Validation of the Clinician Administered PTSD Scale for Children and Adolescents in a Dutch Population.

A cross-cultural validation of the Clinician Administered PTSD Scale for Children and Adolescents in a Dutch population.

Eur J Psychotraumatol. 2013; 4:
Diehle J, de Roos C, Boer F, Lindauer RJ

Trauma-focused interventions for children could be administered more… Continue reading

Differences in Predictors of Traditional and Cyber-Bullying: A 2-Year Longitudinal Study in Korean School Children.

Differences in predictors of traditional and cyber-bullying: a 2-year longitudinal study in Korean school children.

Eur Child Adolesc Psychiatry. 2013 May; 22(5): 309-18
Yang SJ, Stewart R, Kim JM, Kim SW, Shin IS, Dewey ME, Maskey S, Yoon JS… Continue reading

Shame and Guilt in Social Anxiety Disorder: Effects of Cognitive Behavior Therapy and Association With Social Anxiety and Depressive Symptoms.

Shame and guilt in social anxiety disorder: effects of cognitive behavior therapy and association with social anxiety and depressive symptoms.

PLoS One. 2013; 8(4): e61713
Hedman E, Ström P, Stünkel A, Mörtberg E

Social anxiety disorder (SAD), characterized by… Continue reading