herbal extracts

Prevalence Survey of Infection With Treponema Pallidum Among HIV-Positive Patients in Tehran.

Prevalence survey of infection with Treponema pallidum among HIV-positive patients in Tehran.

Asian Pac J Trop Biomed. 2013 Apr; 3(4): 334-6
Badie , Yavari Z, Esmaeeli S, Paydary K, Emamzadeh-Fard S, Seyedalinaghi S, Rasoulinejad M, Mohraz M

To identify… Continue reading

Future Prospects for Pharmacogenetics in the Quest for Personalized Medicine.

Future prospects for pharmacogenetics in the quest for personalized medicine.

J Psychosoc Nurs Ment Health Serv. 2012 Dec; 50(12): 13-6
Howland RH

Understanding pharmacogenetic differences in drug response and tolerability has been an important area of research in personalized… Continue reading

Synthesis and in Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT(7) Receptor Imaging With PET.

Synthesis and In Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT(7) Receptor Imaging with PET.

Filed under: Drug and Alcohol Rehabilitation

ACS Chem Neurosci. 2012 Dec 19; 3(12): 1002-7
Herth MM, Volk B, Pallagi K, Kofoed Bech… Continue reading

Synthesis and in Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT(7) Receptor Imaging With PET.

Synthesis and In Vitro Evaluation of Oxindole Derivatives as Potential Radioligands for 5-HT(7) Receptor Imaging with PET.

Filed under: Drug and Alcohol Rehabilitation

ACS Chem Neurosci. 2012 Dec 19; 3(12): 1002-7
Herth MM, Volk B, Pallagi K, Kofoed Bech… Continue reading

Bioequivalence Study of Two Formulations of Bisoprolol Fumarate Film-Coated Tablets in Healthy Subjects.

Bioequivalence study of two formulations of bisoprolol fumarate film-coated tablets in healthy subjects.

Filed under: Drug and Alcohol Rehabilitation

Drug Des Devel Ther. 2012; 6: 311-6
Tjandrawinata RR, Setiawati E, Yunaidi DA, Santoso ID, Setiawati A, Susanto LW

The present study was conducted to compare the bioavailability of two bisoprolol fumarate 5 mg film-coated tablet formulations (test and reference formulations).This study was a randomized, single-blind, two-period, two-sequence crossover study that included 18 healthy adult male and female subjects under fasting condition. The pharmacokinetic parameters were determined based on the concentrations of bisoprolol (CAS 66722-44-9), using ultraperformance liquid chromatography with a tandem mass spectrometer detector. In each of the two study periods (separated by a washout of 1 week) a single dose of test or reference product was administered. The pharmacokinetic parameters assessed were area under the plasma concentration-time curve from time zero to 48 hours (AUC(t)), AUC from time zero to infinity (AUC(inf)), the peak plasma concentration of the drug (C(max)), time needed to achieve C(max) (t(max)), and the elimination half-life (t(½)).The geometric mean ratios (90% confidence intervals) of the test drug/reference drug for bisoprolol were 101.61% (96.14%-107.38%) for AUC(t), 101.31% (95.66%-107.29%) for AUC(inf), and 100.28% (93.90%-107.09%) for C(max). The differences between the test and reference drug products for bisoprolol t(max) and t(½) values were not statistically significant (P > 0.05).… Continue reading

Depression Medicine: Herbal Depression Medicine: A Viable Alternative to Depression Prescription Drugs?

Herbal depression medicine is commonly promoted as a viable alternative to pharmaceutical treatment of depression. However, the final verdict on the usefulness of herbal depression medicine needs yet to be made. While the effectiveness of herbal anti depressants… Continue reading