Gene expression

Anti-Pancreatic Cancer Deliverables From Sea: First-Hand Evidence on the Efficacy, Molecular Targets and Mode of Action for Multifarious Polyphenols From Five Different Brown-Algae.

Anti-pancreatic cancer deliverables from sea: first-hand evidence on the efficacy, molecular targets and mode of action for multifarious polyphenols from five different brown-algae.

PLoS One. 2013; 8(4): e61977
Aravindan S, Delma CR, Thirugnanasambandan SS, Herman TS, Aravindan N

Pancreatic… Continue reading

Differential Targeting of Brain Stress Circuits With a Selective Glucocorticoid Receptor Modulator.

Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator.

Proc Natl Acad Sci U S A. 2013 Apr 23;
Zalachoras I, Houtman R, Atucha E, Devos R, Tijssen AM, Hu P, Lockey PM, Datson NA, Belanoff… Continue reading

Peripheral Nerve Injury Induces Immediate Increases in Layer v Neuronal Activity.

Peripheral Nerve Injury Induces Immediate Increases in Layer V Neuronal Activity.

Neurorehabil Neural Repair. 2013 Apr 18;
Han Y, Li N, Zeiler SR, Pelled G

BACKGROUND: . Peripheral nerve injury leads to changes in neuronal activity in the contralateral… Continue reading

Optical Coherence Tomography: Clinical Applications in Medical Practice.

Optical Coherence Tomography: Clinical Applications in Medical Practice.

Oman Med J. 2013 Mar; 28(2): 86-91
Al-Mujaini A, Wali UK, Azeem S

Optical Coherence Tomography (OCT) is a success story of scientific and technological co-operation between a physicist and a… Continue reading

Gestational Nicotine Exposure Modifies Myelin Gene Expression in the Brains of Adolescent Rats With Sex Differences.

Gestational nicotine exposure modifies myelin gene expression in the brains of adolescent rats with sex differences.

Transl Psychiatry. 2013; 3: e247
Cao J, Wang J, Dwyer JB, Gautier NM, Wang S, Leslie FM, Li MD

Myelination defects in the… Continue reading

Growing Dairy Heifers Prefer Supplementary Long Straw When Fed a Nutrient-Dense Ration in a Limited Amount.

Growing dairy heifers prefer supplementary long straw when fed a nutrient-dense ration in a limited amount.

J Dairy Sci. 2013 Apr 12;
Greter AM, Prinsen M, Duffield TF, McBride BW, Widowski TM, Devries TJ

The objective of this study was to determine whether limit-fed heifers will choose to consume long particles, rather than short, of a low-nutritive feedstuff to ameliorate rumen function and meet foraging needs. Ten Holstein heifers 261.6 ± 39.2 (mean ± SD) d of age were exposed to each of 2 dietary treatments, in a random order, over 2 successive 7-d treatment periods (4-d adaptation period and a 3-d data collection period) using a crossover design. The treatments were (1) a provision of long particle oat straw (85% of particles > 8 mm; LS) and (2) provision of short particle oat straw (45% of particles >8 mm; SS). Both treatments… Continue reading

Molecular Aging of the Brain, Neuroplasticity, and Vulnerability to Depression and Other Brain-Related Disorders.

Molecular aging of the brain, neuroplasticity, and vulnerability to depression and other brain-related disorders.

Dialogues Clin Neurosci. 2013 Mar; 15(1): 53-65
Sibille E

The increased risk for neurodegenerative and neuropsychiatric disorders associated with extended lifespan has long suggested mechanistic… Continue reading

HDAC3 Is a Negative Regulator of Cocaine-Context-Associated Memory Formation.

HDAC3 Is a Negative Regulator of Cocaine-Context-Associated Memory Formation.

J Neurosci. 2013 Apr 10; 33(15): 6623-32
Rogge GA, Singh H, Dang R, Wood MA

Cocaine-induced neuroplasticity mediated by histone acetylating and deacetylating enzymes may contribute to addiction-like behaviors. For… Continue reading

[Pathomechanisms of Autoantibody Production Against the Nervous System].

[Pathomechanisms of Autoantibody Production against the Nervous System].

Brain Nerve. 2013 Apr; 65(4): 323-32
Arimura K

Abstract In immune-mediated neurological disorders, the production of autoantibodies against the nervous system occurs mainly because of impaired immune tolerance. In myasthenia gravis… Continue reading

Dependence Is Not Addiction and “tolerance” Declares Addiction.

Dependence is not addiction and “tolerance” declares addiction.

JAMA Intern Med. 2013 Apr 8; 173(7): 595-6
Geller AS

HubMed – addiction

 

Acute ketamine-induced neuroplasticity: ribosomal protein S6 phosphorylation expression in drug addiction-related rat brain areas.

Neuroreport. 2013… Continue reading