Gene expression

Cortical-Striatal Gene Expression in Neonatal Hippocampal Lesion-Amplified Cocaine Sensitization.

Cortical-striatal gene expression in neonatal hippocampal lesion-amplified cocaine sensitization.

Genes Brain Behav. 2013 May 17;
Chambers RA, McClintick JN, Sentir AM, Berg SA, Runyan M, Choi KH, Edenberg HJ

Cortical-striatal circuit dysfunction in mental illness may enhance addiction vulnerability. Neonatal ventral hippocampal lesions (NVHL) model this dual diagnosis causality by producing a schizophrenia syndrome with enhanced responsiveness to addictive drugs. Rat genome-wide microarrays containing >24,000 probsets were used to examine separate and co-occurring effects… Continue reading

Optogenetic Strategies to Investigate Neural Circuitry Engaged by Stress.

Optogenetic strategies to investigate neural circuitry engaged by stress.

Behav Brain Res. 2013 May 15;
Sparta DR, Jennings JH, Ung RL, Stuber GD

Optogenetic techniques have given researchers unprecedented access to the function of discrete neural circuit elements and… Continue reading

Non-Destructively Shattered Mesoporous Silica for Protein Drug Delivery.

Non-destructively shattered mesoporous silica for protein drug delivery.

Microporous Mesoporous Mater. 2013 Jul 15; 175: 157-160
Lei C, Chen B, Li X, Qi W, Liu J

Mesoporous silicas have been extensively used for entrapping small chemical molecules and biomacromolecules… Continue reading

Long-Term Fasting in the Anadromous Arctic Charr Is Associated With Down-Regulation of Metabolic Enzyme Activity and Up-Regulation of Leptin A1 and SOCS Expression in the Liver.

Long-term fasting in the anadromous Arctic charr is associated with down-regulation of metabolic enzyme activity and up-regulation of leptin A1 and SOCS expression in the liver.

J Exp Biol. 2013 May 16;
Jørgensen EH, Martinsen M, Strøm V, Hansen… Continue reading

Rapid Detection of Human Cytomegalovirus UL97 and UL54 Mutations Directly From Patient Samples.

Rapid Detection of Human Cytomegalovirus UL97 and UL54 Mutations Directly from Patient Samples.

J Clin Microbiol. 2013 May 15;
Sedlak RH, Castor J, Butler-Wu SM, Chan E, Cook L, Limaye AP, Jerome KR

Human cytomegalovirus (CMV) is a significant… Continue reading

Major Channels Involved in Neuropsychiatric Disorders and Therapeutic Perspectives.

Major channels involved in neuropsychiatric disorders and therapeutic perspectives.

Front Genet. 2013; 4: 76
Imbrici P, Camerino DC, Tricarico D

Voltage-gated ion channels are important mediators of physiological functions in the central nervous system. The cyclic activation of these… Continue reading

Mucosal and Systemic Immune Responses to Mycobacterium Tuberculosis Antigen 85A Following Its Co-Delivery With CpG, MPLA or LTB to the Lungs in Mice.

Mucosal and Systemic Immune Responses to Mycobacterium tuberculosis Antigen 85A following Its Co-Delivery with CpG, MPLA or LTB to the Lungs in Mice.

PLoS One. 2013; 8(5): e63344
Todoroff J, Lemaire MM, Fillee C, Jurion F, Renauld JC, Huygen… Continue reading

Pearls and Pitfalls in Experimental Models of Spreading Depression.

Pearls and pitfalls in experimental models of spreading depression.

Cephalalgia. 2013 Jun; 33(8): 604-13
Ayata C

Spreading depression (SD) is the electrophysiological substrate of migraine aura and a potential trigger for headache. Since its discovery by Leão in 1944,… Continue reading

Protective Effects of Resveratrol on TNF-?-Induced Endothelial Cytotoxicity in Baboon Femoral Arterial Endothelial Cells.

Protective Effects of Resveratrol on TNF-?-Induced Endothelial Cytotoxicity in Baboon Femoral Arterial Endothelial Cells.

J Diabetes Res. 2013; 2013: 185172
Xiao J, Song J, Hodara V, Ford A, Wang XL, Shi Q, Chen L, Vandeberg JL

Endothelial injury induced… Continue reading

Secondary Bacterial Infections of Buruli Ulcer Lesions Before and After Chemotherapy With Streptomycin and Rifampicin.

Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin.

PLoS Negl Trop Dis. 2013 May; 7(5): e2191
Yeboah-Manu D, Kpeli GS, Ruf MT, Asan-Ampah K, Quenin-Fosu K, Owusu-Mireku E, Paintsil A, Lamptey I,… Continue reading