Drug discovery

Effects of the Pimelic Diphenylamide Histone Deacetylase Inhibitor HDACi 4b on the R6/2 and N171-82Q Mouse Models of Huntington’s Disease.

Effects of the Pimelic Diphenylamide Histone Deacetylase Inhibitor HDACi 4b on the R6/2 and N171-82Q Mouse Models of Huntington’s Disease.

PLoS Curr. 2013; 5:
Chen JY, Wang E, Galvan L, Huynh M, Joshi P, Cepeda C, Levine MS

This… Continue reading

Drug and Alcohol Rehabilitation: Protein-Chemical Interaction Prediction via Kernelized Sparse Learning Svm.

Protein-chemical interaction prediction via kernelized sparse learning svm.

Filed under: Drug and Alcohol Rehabilitation

Pac Symp Biocomput. 2013; 41-52
Shi Y, Zhang X, Liao X, Lin G, Schuurmans D

Given the difficulty of experimental determination of drug-protein interactions, there… Continue reading

Frequency and Nature of Drug-Drug Interactions in the Intensive Care Unit.

Frequency and nature of drug-drug interactions in the intensive care unit.

Filed under: Drug and Alcohol Rehabilitation

Pharmacoepidemiol Drug Saf. 2013 Feb 18;
Askari M, Eslami S, Louws M, Wierenga PC, Dongelmans DA, Kuiper RA, Abu-Hanna A

PURPOSE: Drug-drug… Continue reading

Drug and Alcohol Rehabilitation: Diversity and Recombination of Dispersed Ribosomal DNA and Protein Coding Genes in Microsporidia.

Diversity and recombination of dispersed ribosomal DNA and protein coding genes in microsporidia.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2013; 8(2): e55878
Ironside JE

Microsporidian strains are usually classified on the basis of their ribosomal DNA (rDNA)… Continue reading

Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant (XDR) Mycobacterium Tuberculosis in Malaysia.

Draft Genome Sequence of the First Isolate of Extensively Drug-Resistant (XDR) Mycobacterium tuberculosis in Malaysia.

Filed under: Drug and Alcohol Rehabilitation

Genome Announc. 2013 Jan; 1(1):
Ng KP, Yew SM, Chan CL, Chong J, Tang SN, Soo-Hoo TS, Na… Continue reading

Drug and Alcohol Rehabilitation: A Mathematical Model for Thermosensitive Liposomal Delivery of Doxorubicin to Solid Tumour.

A mathematical model for thermosensitive liposomal delivery of Doxorubicin to solid tumour.

Filed under: Drug and Alcohol Rehabilitation

J Drug Deliv. 2013; 2013: 172529
Zhan W, Xu XY

The effectiveness of anticancer treatments is often hampered by the serious… Continue reading

Drug and Alcohol Rehabilitation: Supratherapeutic Dosing of Acetaminophen Among Hospitalized Patients.

Supratherapeutic dosing of acetaminophen among hospitalized patients.

Filed under: Drug and Alcohol Rehabilitation

Arch Intern Med. 2012 Dec 10; 172(22): 1721-8
Zhou L, Maviglia SM, Mahoney LM, Chang F, Orav EJ, Plasek J, Boulware LJ, Bates DW, Rocha RA… Continue reading

Addiction Rehab: Worming Our Way to Alzheimer’s Disease Drug Discovery.

Worming our way to Alzheimer’s disease drug discovery.

Filed under: Addiction Rehab

Biol Psychiatry. 2013 Mar 1; 73(5): 396-8
Iyer S, Pierce-Shimomura JT

HubMed – addiction

 

Modafinil Modulates Resting-State Functional Network Connectivity and Cognitive Control in Alcohol-DependentPatients.

Filed… Continue reading

Drug and Alcohol Rehabilitation: First in Vitro and in Vivo Results of an Anti-Human CD133-Antibody Coated Coronary Stent in the Porcine Model.

First in vitro and in vivo results of an anti-human CD133-antibody coated coronary stent in the porcine model.

Filed under: Drug and Alcohol Rehabilitation

Clin Res Cardiol. 2013 Feb 10;
Sedaghat A, Sinning JM, Paul K, Kirfel G, Nickenig… Continue reading

Update in Pediatric Anaphylaxis: A Systematic Review.

Update in Pediatric Anaphylaxis: A Systematic Review.

Filed under: Drug and Alcohol Rehabilitation

Clin Pediatr (Phila). 2013 Feb 7;
Chipps BE

Anaphylaxis is common in children and has many differences across age groups. A systematic review of the literature… Continue reading