controlled trial

Psychosocial and Psychological Interventions for Preventing Postpartum Depression.

Psychosocial and psychological interventions for preventing postpartum depression.

Cochrane Database Syst Rev. 2013; 2: CD001134
Dennis CL, Dowswell T

Epidemiological studies and meta-analyses of predictive studies have consistently demonstrated the importance of psychosocial and psychological variables as postpartum depression… Continue reading

Interventions for Preventing or Reducing Domestic Violence Against Pregnant Women.

Interventions for preventing or reducing domestic violence against pregnant women.

Cochrane Database Syst Rev. 2013; 2: CD009414
Jahanfar S, Janssen PA, Howard LM, Dowswell T

Domestic violence during pregnancy is a major public health concern. This preventable risk factor… Continue reading

Physical Rehabilitation for Older People in Long-Term Care.

Physical rehabilitation for older people in long-term care.

Cochrane Database Syst Rev. 2013; 2: CD004294
Crocker T, Forster A, Young J, Brown L, Ozer S, Smith J, Green J, Hardy J, Burns E, Glidewell E, Greenwood DC

The worldwide… Continue reading

Resilience in Shock and Swim Stress Models of Depression.

Resilience in shock and swim stress models of depression.

Front Behav Neurosci. 2013; 7: 14
Drugan RC, Christianson JP, Warner TA, Kent S

Experimental models of depression often entail exposing a rodent to a stressor and subsequently characterizing changes… Continue reading

Functional and Structural Neural Network Characterization of Serotonin Transporter Knockout Rats.

Functional and structural neural network characterization of serotonin transporter knockout rats.

PLoS One. 2013; 8(2): e57780
van der Marel K, Homberg JR, Otte WM, Dijkhuizen RM

Brain serotonin homeostasis is crucially maintained by the serotonin transporter (5-HTT), and its… Continue reading

Combining Cognitive-Behavioral Therapy and Milnacipran for Fibromyalgia: A Feasibility Randomized-Controlled Trial.

Combining Cognitive-Behavioral Therapy and Milnacipran for Fibromyalgia: A Feasibility Randomized-controlled Trial.

Clin J Pain. 2013 Feb 26;
Ang DC, Jensen MP, Steiner JL, Hilligoss J, Gracely RH, Saha C

OBJECTIVES:: To evaluate the feasibility of a randomized-controlled trial and to obtain estimates of the effects of combined cognitive-behavioral therapy (CBT) and milnacipran for the treatment of fibromyalgia. METHODS:: Fifty-eight patients with fibromyalgia were randomized to 1 of the 3 treatment arms: (1) combination therapy (n=20); (2) milnacipran+education (n=19); and (3) placebo+CBT (n=19). Patients received either milnacipran (100 mg/d) or placebo. Patients also received 8 sessions of phone-delivered CBT or educational instructions, but only from baseline to week 9. Assessments were conducted at baseline, week 9, and 21. The primary endpoints were baseline to week 21 changes in weekly average pain intensity and physical function (SF-36 physical function scale). RESULTS:: Compared with milnacipran, combination therapy demonstrated a moderate effect on improving SF-36 physical function [SE=9.42 (5.48), P=0.09, effect size=0.60] and in reducing weekly average pain intensity [mean difference (SE)=-1.18 (0.62), P=0.07, effect size=0.67]. Compared with milnacipran, CBT had a moderate to large effect in improving SF-36 physical function [mean difference (SE)=11.0 (5.66), P=0.06, effect size=0.70]. Despite the presence of concomitant centrally acting therapies, dropout rate was lower than anticipated (15% at week 21). Importantly, at least 6 out of the 8 phone-based therapy sessions were successfully completed by 89% of the patients; and adherence to the treatment protocols was >95%. CONCLUSIONS:: In this pilot study, a therapeutic approach that… Continue reading

Factors Associated With Outcome After Superior Hypogastric Plexus Neurolysis in Cancer Patients.

Factors Associated With Outcome after Superior Hypogastric Plexus Neurolysis in Cancer Patients.

Clin J Pain. 2013 Feb 26;
Kroll CE, Schartz B, Gonzalez-Fernandez M, Gordon AH, Babade M, Erdek MA, Mekhail N, Cohen SP

OBJECTIVE:: Superior hypogastric plexus neurolysis… Continue reading

Cover Image, Volume 34, Issue 9.

Cover image, volume 34, issue 9.

J Comput Chem. 2013 Apr 5; 34(9): i-ii

The rapid development of drug resistance in microbes, the toxicity, and side effects of existing anti-infectious drugs are factors stimulating the effort directed toward a… Continue reading

The Association Between Self-Reported History of Physical Diseases and Psychological Distress in a Community-Dwelling Japanese Population: The Ohsaki Cohort 2006 Study.

The association between self-reported history of physical diseases and psychological distress in a community-dwelling Japanese population: the Ohsaki Cohort 2006 Study.

Eur J Public Health. 2013 Feb 26;
Nakaya N, Kogure M, Saito-Nakaya K, Tomata Y, Sone T, Kakizaki… Continue reading

Neuroplasticity-Based Brain Stimulation Interventions in the Study and Treatment of Schizophrenia: A Review.

Neuroplasticity-based brain stimulation interventions in the study and treatment of schizophrenia: a review.

Can J Psychiatry. 2013 Feb; 58(2): 93-8
Rajji TK, Rogasch NC, Daskalakis ZJ, Fitzgerald PB

We reviewed novel brain stimulation approaches that modify neuroplasticity and are… Continue reading