clinical trials

In Vitro Selection of Mutant HDM2 Resistant to Nutlin Inhibition.

In Vitro Selection of Mutant HDM2 Resistant to Nutlin Inhibition.

PLoS One. 2013; 8(4): e62564
Wei SJ, Joseph T, Sim AY, Yurlova L, Zolghadr K, Lane D, Verma C, Ghadessy F

HDM2 binds to the p53 tumour suppressor and… Continue reading

Management of Opioid Addiction in Primary Care: A Pragmatic Approach Prioritising Wellbeing Not Ideology.

Management of opioid addiction in primary care: a pragmatic approach prioritising wellbeing not ideology.

Br J Gen Pract. 2013 May; 63(610): 231-2
Lawson E

HubMed – addiction

 

A narrative review of yoga and mindfulness as complementary therapies for… Continue reading

A New Class of Small Molecule Inhibitor of BMP Signaling.

A New Class of Small Molecule Inhibitor of BMP Signaling.

PLoS One. 2013; 8(4): e62721
Sanvitale CE, Kerr G, Chaikuad A, Ramel MC, Mohedas AH, Reichert S, Wang Y, Triffitt JT, Cuny GD, Yu PB, Hill CS, Bullock AN… Continue reading

Randomized Trial Demonstrates That Extended-Release Epidural Morphine May Provide Safe Pain Control for Lumbar Surgery Patients.

Randomized trial demonstrates that extended-release epidural morphine may provide safe pain control for lumbar surgery patients.

Surg Neurol Int. 2013; 4(Suppl 2): S51-7
Offley SC, Coyne E, Horodyski M, Rubery PT, Zeidman SM, Rechtine GR

Safe and effective postoperative… Continue reading

Objective Assessment of Joint Stiffness: A Clinically Oriented Hardware and Software Device With an Application to the Shoulder Joint.

Objective Assessment of Joint Stiffness: A Clinically Oriented Hardware and Software Device with an Application to the Shoulder Joint.

J Nov Physiother. 2012 Aug 30; 2(7):
McQuade K, Price R, Liu N, Ciol MA

Examination of articular joints is… Continue reading

Suboxone Pharma Foibles/FDA Does Its Job Well.

Suboxone Pharma Foibles/FDA Does Its Job Well.

R I Med J (2013). 2013; 96(4): 13
Gordon A, Kretzschmar A, Gilbert E

HubMed – addiction

 

Pyrvinium targets autophagy addiction to promote cancer cell death.

Cell Death Dis. 2013;… Continue reading

Correlation of Angiogenic Biomarker Signatures With Clinical Outcomes in Metastatic Colorectal Cancer Patients Receiving Capecitabine, Oxaliplatin, and Bevacizumab.

Correlation of angiogenic biomarker signatures with clinical outcomes in metastatic colorectal cancer patients receiving capecitabine, oxaliplatin, and bevacizumab.

Cancer Med. 2013 Apr; 2(2): 234-42
Liu Y, Starr MD, Bulusu A, Pang H, Wong NS, Honeycutt W, Amara A, Hurwitz… Continue reading

Find Novel Dual-Agonist Drugs for Treating Type 2 Diabetes by Means of Cheminformatics.

Find novel dual-agonist drugs for treating type 2 diabetes by means of cheminformatics.

Drug Des Devel Ther. 2013; 7: 279-88
Liu L, Ma Y, Wang RL, Xu WR, Wang SQ, Chou KC

The high prevalence of type 2 diabetes… Continue reading

Update on the Treatment of Non-Small-Cell Lung Cancer: Focus on the Cost-Effectiveness of New Agents.

Update on the treatment of non-small-cell lung cancer: focus on the cost-effectiveness of new agents.

Clinicoecon Outcomes Res. 2013; 5: 137-41
Vergnenègre A, Borget I, Chouaid C

The incidence of lung cancer and the cost of drug treatment have… Continue reading

Can MDMA Play a Role in the Treatment of Substance Abuse?

Can MDMA Play a Role in the Treatment of Substance Abuse?

Curr Drug Abuse Rev. 2013 Apr 29;
Jerome L, Shira Schuster MA, Yazar-Klosinski BB

A wider array of treatments are needed for people with substance abuse disorders. Some… Continue reading