Clinical trial

Oral Rehabilitation of an Edentulous Patient Using Two-Segment Le Fort I Repositioning and Implant-Supported Fixed Prostheses.

Oral rehabilitation of an edentulous patient using two-segment le fort I repositioning and implant-supported fixed prostheses.

Int J Oral Maxillofac Implants. 2013 Mar-Apr; 28(2): e106-11
Abdel-Azim T, Fantuzzo J, Batalocco G, Cho S, Ercoli C, Morton D

Anteroposterior (AP)… Continue reading

Drug Costs in Prediabetes and Undetected Diabetes Compared With Diagnosed Diabetes and Normal Glucose Tolerance: Results From the Population-Based KORA Survey in Germany.

Drug Costs in Prediabetes and Undetected Diabetes Compared With Diagnosed Diabetes and Normal Glucose Tolerance: Results From the Population-Based KORA Survey in Germany.

Diabetes Care. 2013 Apr; 36(4): e53-4
Icks A, Claessen H, Strassburger K, Tepel M, Waldeyer R,… Continue reading

Post Laryngectomy Speech Rehabilitation Outcome in Elderly Patients.

Post laryngectomy speech rehabilitation outcome in elderly patients.

Eur Arch Otorhinolaryngol. 2013 Mar 22;
Cocuzza S, Bonfiglio M, Grillo C, Maiolino L, Malaguarnera M, Martines F, Serra A

The aim of our work has been to evaluate the different options of tracheoesophageal voice rehabilitation in over 70-year-old patients, who had undergone laryngectomy, assessing advantages and drawbacks of this method of vocal recovery. A retrospective study has been carried out. This has included 40 subjects, all aged more than 70 years old, who have been referred to tracheoesophageal voice rehabilitation. It has been realized a phonatory fistula between trachea and esophagus with prosthesis positioning by means of a primary puncture in 18 cases and it has been realized a secondary puncture in 22 cases. The results gathered in these patients were compared with data obtained from a group made of 39 patients, less than 70 years of age that therefore represented our control group. In primary tracheoesophageal puncture (TEP), the short-term success was 67 %, while in the 22 cases who underwent secondary TEP, the short-term success was 64 %. After 2 years from TEP, the long-term success was 82.5 %. In the control group, the short-term success was 65 % in primary TEP and 73 % in secondary TEP. After 2 years from TEP, the long-term success was 77 %. The evaluation of the results has shown the absence of a statistically significant difference both as regards complications incidence, during and after surgery (p > 0.9) and as regards overall success ratio of prosthesis implants between the two groups (p > 0.7). The possibilities of tracheoesophageal recovery of elderly patients do… Continue reading

Reduced Susceptibility of Plasmodium Falciparum to Artesunate in Southern Myanmar.

Reduced Susceptibility of Plasmodium falciparum to Artesunate in Southern Myanmar.

PLoS One. 2013; 8(3): e57689
Kyaw MP, Nyunt MH, Chit K, Aye MM, Aye KH, Aye MM, Lindegardh N, Tarning J, Imwong M, Jacob CG, Rasmussen C, Perin J,… Continue reading

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Ottawa company pushes alternative to depression treatment
An Ottawa company has a new alternative to anti-depressant medication that could soon face a clinical trial, but the… Continue reading

Effect of Amphetamine on the Clock Gene Expression in Rat Striatum.

Effect of amphetamine on the clock gene expression in rat striatum.

Neurosci Lett. 2013 Mar 18;
Wongchitrat P, Mukda S, Phansuwan-Pujito P, Govitrapong P

Drug addicts have severe disruptions in many physiological and behavioral rhythms, such as the sleep/wake… Continue reading

RASopathic Skin Eruptions During Vemurafenib Therapy.

RASopathic Skin Eruptions during Vemurafenib Therapy.

PLoS One. 2013; 8(3): e58721
Rinderknecht JD, Goldinger SM, Rozati S, Kamarashev J, Kerl K, French LE, Dummer R, Belloni B

Vemurafenib is a potent inhibitor of V600 mutant BRAF with significant impact… Continue reading

Role of Ess1 in Growth, Morphogenetic Switching, and RNA Polymerase II Transcription in Candida Albicans.

Role of Ess1 in Growth, Morphogenetic Switching, and RNA Polymerase II Transcription in Candida albicans.

PLoS One. 2013; 8(3): e59094
Samaranayake D, Atencio D, Morse R, Wade JT, Chaturvedi V, Hanes SD

Candida albicans is a fungal pathogen that… Continue reading

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How to Go to a Yankee Game — 2013 Edition
Entering by Gate 2 will… Continue reading

Yellow Fluorescent Protein-Based Assay to Measure GABAA Channel Activation and Allosteric Modulation in CHO-K1 Cells.

Yellow Fluorescent Protein-Based Assay to Measure GABAA Channel Activation and Allosteric Modulation in CHO-K1 Cells.

PLoS One. 2013; 8(3): e59429
Johansson T, Norris T, Peilot-Sjögren H

The ?-aminobutyric acid A (GABAA) ion channels are important drug targets for treatment… Continue reading