cell line

Crosstalk From Non-Cancerous Mitochondria Can Inhibit Tumor Properties of Metastatic Cells by Suppressing Oncogenic Pathways.

Crosstalk from non-cancerous mitochondria can inhibit tumor properties of metastatic cells by suppressing oncogenic pathways.

PLoS One. 2013; 8(5): e61747
Kaipparettu BA, Ma Y, Park JH, Lee TL, Zhang Y, Yotnda P, Creighton CJ, Chan WY, Wong LJ

Mitochondrial-nucleus… Continue reading

Protective Effects of Resveratrol on TNF-?-Induced Endothelial Cytotoxicity in Baboon Femoral Arterial Endothelial Cells.

Protective Effects of Resveratrol on TNF-?-Induced Endothelial Cytotoxicity in Baboon Femoral Arterial Endothelial Cells.

J Diabetes Res. 2013; 2013: 185172
Xiao J, Song J, Hodara V, Ford A, Wang XL, Shi Q, Chen L, Vandeberg JL

Endothelial injury induced… Continue reading

Sustained EKR Inhibition by EGFR Targeting Therapies Is a Predictive Factor for Synergistic Cytotoxicity With PDT as Neoadjuvant Therapy.

Sustained EKR inhibition by EGFR targeting therapies is a predictive factor for synergistic cytotoxicity with PDT as neoadjuvant therapy.

Biochim Biophys Acta. 2013 Mar; 1830(3): 2659-70
Weyergang A, Selbo PK, Berg K

Tyrosin kinase inhibitors (TKIs) and monoclonal antibodies… Continue reading

Comparison of Responses of Human Melanoma Cell Lines to MEK and BRAF Inhibitors.

Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.

Front Genet. 2013; 4: 66
Stones CJ, Kim JE, Joseph WR, Leung E, Marshall ES, Finlay GJ, Shelling AN, Baguley BC

The NRAS and BRAF genes… Continue reading

Secondary Bacterial Infections of Buruli Ulcer Lesions Before and After Chemotherapy With Streptomycin and Rifampicin.

Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin.

PLoS Negl Trop Dis. 2013 May; 7(5): e2191
Yeboah-Manu D, Kpeli GS, Ruf MT, Asan-Ampah K, Quenin-Fosu K, Owusu-Mireku E, Paintsil A, Lamptey I,… Continue reading

Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(Ethylsulfinyl)-6-(Trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.

Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.

Drug Metab Dispos. 2013 May 7;
Eng H, Sharma R, McDonald TS, Edmonds DJ, Fortin JP, Li X, Stevens… Continue reading

Viability Reagent, PrestoBlue, in Comparison With Other Available Reagents, Utilized in Cytotoxicity and Antimicrobial Assays.

Viability Reagent, PrestoBlue, in Comparison with Other Available Reagents, Utilized in Cytotoxicity and Antimicrobial Assays.

Int J Microbiol. 2013; 2013: 420601
Lall N, Henley-Smith CJ, De Canha MN, Oosthuizen CB, Berrington D

This study compared different commercially available viability… Continue reading

Mitochondrial Dysfunction, Oxidative Stress, and Major Depressive Disorder.

Mitochondrial dysfunction, oxidative stress, and major depressive disorder.

Neuropsychiatr Dis Treat. 2013; 9: 567-73
Tobe EH

There is controversy about depression being a physical illness, in part because a reproducible, sensitive, and specific biologic marker is not available. However,… Continue reading

Machine Learning Prediction of Cancer Cell Sensitivity to Drugs Based on Genomic and Chemical Properties.

Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties.

PLoS One. 2013; 8(4): e61318
Menden MP, Iorio F, Garnett M, McDermott U, Benes CH, Ballester PJ, Saez-Rodriguez J

Predicting the response of a… Continue reading

A New Class of Small Molecule Inhibitor of BMP Signaling.

A New Class of Small Molecule Inhibitor of BMP Signaling.

PLoS One. 2013; 8(4): e62721
Sanvitale CE, Kerr G, Chaikuad A, Ramel MC, Mohedas AH, Reichert S, Wang Y, Triffitt JT, Cuny GD, Yu PB, Hill CS, Bullock AN… Continue reading