Cell cycle

Randomized Trials Built on Sand: Examples From COPD, Hormone Therapy, and Cancer.

Randomized Trials Built on Sand: Examples from COPD, Hormone Therapy, and Cancer.

Rambam Maimonides Med J. 2012 Jul; 3(3): e0014
Suissa S

The randomized controlled trial is the fundamental study design to evaluate the effectiveness of medications and receive… Continue reading →

Differential Impact of Two Risk Communications on Antipsychotic Prescribing to People With Dementia in Scotland: Segmented Regression Time Series Analysis 2001-2011.

Differential impact of two risk communications on antipsychotic prescribing to people with dementia in Scotland: segmented regression time series analysis 2001-2011.

PLoS One. 2013; 8(7): e68976
Guthrie B, Clark SA, Reynish EL, McCowan C, Morales DR

Regulatory risk communications… Continue reading →

PEGylated Interferon Beta-1a in the Treatment of Multiple Sclerosis – an Update.

PEGylated interferon beta-1a in the treatment of multiple sclerosis – an update.

Biologics. 2013; 7: 131-138
Reuss R

Current standard immunomodulatory therapy with interferons (IFNs) for relapsing-remitting multiple sclerosis (MS) exhibits proven, but limited, efficacy and increased side effects… Continue reading →

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation.

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation.

PLoS One. 2013; 8(6): e67782
Guha M, Castellanos-Rizaldos E, Makrigiorgos GM

Non-small cell lung cancer (NSCLC) patients treated with small molecule EGFR inhibitors, such as gefitinib, frequently develop… Continue reading →

Animal Models of Nicotine Exposure: Relevance to Second-Hand Smoking, Electronic Cigarette Use, and Compulsive Smoking.

Animal models of nicotine exposure: relevance to second-hand smoking, electronic cigarette use, and compulsive smoking.

Front Psychiatry. 2013; 4: 41
Cohen A, George O

Much evidence indicates that individuals use tobacco primarily to experience the psychopharmacological properties of nicotine… Continue reading →

Stachydrine Ameliorates High-Glucose Induced Endothelial Cell Senescence and SIRT1 Downregulation.

Stachydrine ameliorates high-glucose induced endothelial cell senescence and SIRT1 downregulation.

J Cell Biochem. 2013 Jun 6;
Servillo L, D’Onofrio N, Longobardi L, Sirangelo I, Giovane A, Cautela D, Castaldo D, Giordano A, Balestrieri ML

Hyperglycaemia, a characteristic feature of… Continue reading →

Influence of Adult Height on Rheumatoid Arthritis: Association With Disease Activity, Impairment of Joint Function and Overall Disability.

Influence of Adult Height on Rheumatoid Arthritis: Association with Disease Activity, Impairment of Joint Function and Overall Disability.

PLoS One. 2013; 8(5): e64862
Chen Y, Yu Z, Packham JC, Mattey DL

To investigate whether normal variation of adult height… Continue reading →

Non-Destructively Shattered Mesoporous Silica for Protein Drug Delivery.

Non-destructively shattered mesoporous silica for protein drug delivery.

Microporous Mesoporous Mater. 2013 Jul 15; 175: 157-160
Lei C, Chen B, Li X, Qi W, Liu J

Mesoporous silicas have been extensively used for entrapping small chemical molecules and biomacromolecules… Continue reading →

Association Among Stress, Salivary Cortisol Levels, and Chronic Periodontitis.

Association among stress, salivary cortisol levels, and chronic periodontitis.

J Periodontal Implant Sci. 2013 Apr; 43(2): 96-100
Refulio Z, Rocafuerte M, de la Rosa M, Mendoza G, Chambrone L

Chronic periodontitis (CP) seems to be associated with stress and… Continue reading →

Major Channels Involved in Neuropsychiatric Disorders and Therapeutic Perspectives.

Major channels involved in neuropsychiatric disorders and therapeutic perspectives.

Front Genet. 2013; 4: 76
Imbrici P, Camerino DC, Tricarico D

Voltage-gated ion channels are important mediators of physiological functions in the central nervous system. The cyclic activation of these… Continue reading →