Cell cycle

Randomized Trials Built on Sand: Examples From COPD, Hormone Therapy, and Cancer.

Randomized Trials Built on Sand: Examples from COPD, Hormone Therapy, and Cancer.

Rambam Maimonides Med J. 2012 Jul; 3(3): e0014
Suissa S

The randomized controlled trial is the fundamental study design to evaluate the effectiveness of medications and receive… Continue reading

Differential Impact of Two Risk Communications on Antipsychotic Prescribing to People With Dementia in Scotland: Segmented Regression Time Series Analysis 2001-2011.

Differential impact of two risk communications on antipsychotic prescribing to people with dementia in Scotland: segmented regression time series analysis 2001-2011.

PLoS One. 2013; 8(7): e68976
Guthrie B, Clark SA, Reynish EL, McCowan C, Morales DR

Regulatory risk communications… Continue reading

PEGylated Interferon Beta-1a in the Treatment of Multiple Sclerosis – an Update.

PEGylated interferon beta-1a in the treatment of multiple sclerosis – an update.

Biologics. 2013; 7: 131-138
Reuss R

Current standard immunomodulatory therapy with interferons (IFNs) for relapsing-remitting multiple sclerosis (MS) exhibits proven, but limited, efficacy and increased side effects… Continue reading

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation.

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation.

PLoS One. 2013; 8(6): e67782
Guha M, Castellanos-Rizaldos E, Makrigiorgos GM

Non-small cell lung cancer (NSCLC) patients treated with small molecule EGFR inhibitors, such as gefitinib, frequently develop… Continue reading

Animal Models of Nicotine Exposure: Relevance to Second-Hand Smoking, Electronic Cigarette Use, and Compulsive Smoking.

Animal models of nicotine exposure: relevance to second-hand smoking, electronic cigarette use, and compulsive smoking.

Front Psychiatry. 2013; 4: 41
Cohen A, George O

Much evidence indicates that individuals use tobacco primarily to experience the psychopharmacological properties of nicotine… Continue reading

Stachydrine Ameliorates High-Glucose Induced Endothelial Cell Senescence and SIRT1 Downregulation.

Stachydrine ameliorates high-glucose induced endothelial cell senescence and SIRT1 downregulation.

J Cell Biochem. 2013 Jun 6;
Servillo L, D’Onofrio N, Longobardi L, Sirangelo I, Giovane A, Cautela D, Castaldo D, Giordano A, Balestrieri ML

Hyperglycaemia, a characteristic feature of… Continue reading

Influence of Adult Height on Rheumatoid Arthritis: Association With Disease Activity, Impairment of Joint Function and Overall Disability.

Influence of Adult Height on Rheumatoid Arthritis: Association with Disease Activity, Impairment of Joint Function and Overall Disability.

PLoS One. 2013; 8(5): e64862
Chen Y, Yu Z, Packham JC, Mattey DL

To investigate whether normal variation of adult height… Continue reading

Non-Destructively Shattered Mesoporous Silica for Protein Drug Delivery.

Non-destructively shattered mesoporous silica for protein drug delivery.

Microporous Mesoporous Mater. 2013 Jul 15; 175: 157-160
Lei C, Chen B, Li X, Qi W, Liu J

Mesoporous silicas have been extensively used for entrapping small chemical molecules and biomacromolecules… Continue reading

Association Among Stress, Salivary Cortisol Levels, and Chronic Periodontitis.

Association among stress, salivary cortisol levels, and chronic periodontitis.

J Periodontal Implant Sci. 2013 Apr; 43(2): 96-100
Refulio Z, Rocafuerte M, de la Rosa M, Mendoza G, Chambrone L

Chronic periodontitis (CP) seems to be associated with stress and… Continue reading

Major Channels Involved in Neuropsychiatric Disorders and Therapeutic Perspectives.

Major channels involved in neuropsychiatric disorders and therapeutic perspectives.

Front Genet. 2013; 4: 76
Imbrici P, Camerino DC, Tricarico D

Voltage-gated ion channels are important mediators of physiological functions in the central nervous system. The cyclic activation of these… Continue reading