cancer cells

Effectiveness of Miltefosine Treatment in Targeting Anti-Leishmanial HO-1/Nrf-2-Mediated Oxidative Responses in Visceral Leishmaniasis Patients.

Effectiveness of miltefosine treatment in targeting anti-leishmanial HO-1/Nrf-2-mediated oxidative responses in visceral leishmaniasis patients.

J Antimicrob Chemother. 2013 May 31;
Das S, Pandey K, Rabidas VN, Mandal A, Das P

OBJECTIVES: Miltefosine, an alkylphosphocholine anti-cancer drug, exhibits direct activity… Continue reading

Beyond Anti-VEGF: Dual-Targeting Antiangiogenic and Antiproliferative Therapy.

Beyond anti-VEGF: dual-targeting antiangiogenic and antiproliferative therapy.

Am J Transl Res. 2013; 5(4): 393-403
Chen CT, Hung MC

Antiangiogenesis is a promising antitumor strategy that inhibits tumor vascular formation to suppress tumor growth. Specifically, targeting VEGF has shown therapeutic… Continue reading

BcL-xL Conformational Changes Upon Fragment Binding Revealed by NMR.

BcL-xL Conformational Changes upon Fragment Binding Revealed by NMR.

PLoS One. 2013; 8(5): e64400
Aguirre C, Ten Brink T, Walker O, Guillière F, Davesne D, Krimm I

Protein-protein interactions represent difficult but increasingly important targets for the design of… Continue reading

Proteomic Approach Toward Molecular Backgrounds of Drug Resistance of Osteosarcoma Cells in Spheroid Culture System.

Proteomic approach toward molecular backgrounds of drug resistance of osteosarcoma cells in spheroid culture system.

Proteomics. 2013 May 28;
Arai K, Sakamoto R, Kubota D, Kondo T

Chemoresistance is one of the most critical prognostic factors in osteosarcoma, and… Continue reading

High-Throughput Screening for GPR119 Modulators Identifies a Novel Compound With Anti-Diabetic Efficacy in Db/db Mice.

High-Throughput Screening for GPR119 Modulators Identifies a Novel Compound with Anti-Diabetic Efficacy in db/db Mice.

PLoS One. 2013; 8(5): e63861
Zhang M, Feng Y, Wang J, Zhao J, Li T, He M, Yang D, Nosjean O, Boutin J, Renard… Continue reading

Influence of Adult Height on Rheumatoid Arthritis: Association With Disease Activity, Impairment of Joint Function and Overall Disability.

Influence of Adult Height on Rheumatoid Arthritis: Association with Disease Activity, Impairment of Joint Function and Overall Disability.

PLoS One. 2013; 8(5): e64862
Chen Y, Yu Z, Packham JC, Mattey DL

To investigate whether normal variation of adult height… Continue reading

Assessing a Potential Role of Host Pannexin 1 During Chlamydia Trachomatis Infection.

Assessing a Potential Role of Host Pannexin 1 during Chlamydia trachomatis Infection.

PLoS One. 2013; 8(5): e63732
McKuen MJ, Dahl G, Fields KA

Pannexin 1 (Panx1) is a plasma membrane channel glycoprotein that plays a role in innate immune… Continue reading

In Vivo Anticancer Activities of Benzophenone Semicarbazone Against Ehrlich Ascites Carcinoma Cells in Swiss Albino Mice.

In vivo Anticancer Activities of Benzophenone Semicarbazone against Ehrlich Ascites Carcinoma Cells in Swiss Albino Mice.

Cancer Biol Med. 2012 Dec; 9(4): 242-247
Islam K, Ali SM, Jesmin M, Khanam JA

Benzophenone semicarbazone (BSC) was synthesized and characterized to… Continue reading

Delirium Associated With Donepezil in a Patient With Alzheimer’s Disease: A Case Report.

Delirium associated with donepezil in a patient with Alzheimer’s disease: a case report.

Iran J Psychiatry. 2013 Mar; 8(1): 59-60
Mollazadeh-Moghaddam K, Jamali A, Adili-Aghdam F, Akhondzadeh S

Donepezil, a member of the acetylcholinesterase inhibitor family, is approved for… Continue reading

Rapid Detection of Human Cytomegalovirus UL97 and UL54 Mutations Directly From Patient Samples.

Rapid Detection of Human Cytomegalovirus UL97 and UL54 Mutations Directly from Patient Samples.

J Clin Microbiol. 2013 May 15;
Sedlak RH, Castor J, Butler-Wu SM, Chan E, Cook L, Limaye AP, Jerome KR

Human cytomegalovirus (CMV) is a significant… Continue reading