cancer cell

A Review of Targeted Therapies Evaluated by the Pediatric Preclinical Testing Program for Osteosarcoma.

A review of targeted therapies evaluated by the pediatric preclinical testing program for osteosarcoma.

Front Oncol. 2013; 3: 132
Sampson VB, Gorlick R, Kamara D, Anders Kolb E

Osteosarcoma, the most common malignant bone tumor of childhood, is a… Continue reading

Overview of Cancer Stem Cells (CSCs) and Mechanisms of Their Regulation: Implications for Cancer Therapy.

Overview of Cancer Stem Cells (CSCs) and Mechanisms of Their Regulation: Implications for Cancer Therapy.

Curr Protoc Pharmacol. 2013 Jun; Chapter 14: Unit14.25
Bao B, Ahmad A, Azmi AS, Ali S, Sarkar FH

The identification of small subpopulations of… Continue reading

Scavenger Receptor-AI-Targeted Iron Oxide Nanoparticles for in Vivo MRI Detection of Atherosclerotic Lesions.

Scavenger Receptor-AI-Targeted Iron Oxide Nanoparticles for In Vivo MRI Detection of Atherosclerotic Lesions.

Arterioscler Thromb Vasc Biol. 2013 Jun 6;
Segers FM, den Adel B, Bot I, van der Graaf LM, van der Veer E, Gonzalez W, Raynal I,… Continue reading

High Prevalence of HIV-1 Intersubtype B’/C Recombinants Among Injecting Drug Users in Dehong, China.

High Prevalence of HIV-1 Intersubtype B’/C Recombinants among Injecting Drug Users in Dehong, China.

PLoS One. 2013; 8(5): e65337
Han X, An M, Zhao B, Duan S, Yang S, Xu J, Zhang M, McGoogan JM, Takebe Y, Shang H… Continue reading

Fucoidan Inhibits the Growth of Hepatocellular Carcinoma Independent of Angiogenesis.

Fucoidan inhibits the growth of hepatocellular carcinoma independent of angiogenesis.

Evid Based Complement Alternat Med. 2013; 2013: 692549
Zhu C, Cao R, Zhang SX, Man YN, Wu XZ

Some sulphated polysaccharides can bind bFGF but are unable to present… Continue reading

Medication-Assisted Treatment of Opiate Dependence Is Gaining Favor.

Medication-assisted treatment of opiate dependence is gaining favor.

Cleve Clin J Med. 2013 Jun; 80(6): 345-9
Jerry JM, Collins GB

People addicted to opiates are more likely to avoid returning to these drugs if they participate in a program… Continue reading

Effectiveness of Miltefosine Treatment in Targeting Anti-Leishmanial HO-1/Nrf-2-Mediated Oxidative Responses in Visceral Leishmaniasis Patients.

Effectiveness of miltefosine treatment in targeting anti-leishmanial HO-1/Nrf-2-mediated oxidative responses in visceral leishmaniasis patients.

J Antimicrob Chemother. 2013 May 31;
Das S, Pandey K, Rabidas VN, Mandal A, Das P

OBJECTIVES: Miltefosine, an alkylphosphocholine anti-cancer drug, exhibits direct activity… Continue reading

Beyond Anti-VEGF: Dual-Targeting Antiangiogenic and Antiproliferative Therapy.

Beyond anti-VEGF: dual-targeting antiangiogenic and antiproliferative therapy.

Am J Transl Res. 2013; 5(4): 393-403
Chen CT, Hung MC

Antiangiogenesis is a promising antitumor strategy that inhibits tumor vascular formation to suppress tumor growth. Specifically, targeting VEGF has shown therapeutic… Continue reading

BcL-xL Conformational Changes Upon Fragment Binding Revealed by NMR.

BcL-xL Conformational Changes upon Fragment Binding Revealed by NMR.

PLoS One. 2013; 8(5): e64400
Aguirre C, Ten Brink T, Walker O, Guillière F, Davesne D, Krimm I

Protein-protein interactions represent difficult but increasingly important targets for the design of… Continue reading

Proteomic Approach Toward Molecular Backgrounds of Drug Resistance of Osteosarcoma Cells in Spheroid Culture System.

Proteomic approach toward molecular backgrounds of drug resistance of osteosarcoma cells in spheroid culture system.

Proteomics. 2013 May 28;
Arai K, Sakamoto R, Kubota D, Kondo T

Chemoresistance is one of the most critical prognostic factors in osteosarcoma, and… Continue reading