addictive drugs

Cortical-Striatal Gene Expression in Neonatal Hippocampal Lesion-Amplified Cocaine Sensitization.

Cortical-striatal gene expression in neonatal hippocampal lesion-amplified cocaine sensitization.

Genes Brain Behav. 2013 May 17;
Chambers RA, McClintick JN, Sentir AM, Berg SA, Runyan M, Choi KH, Edenberg HJ

Cortical-striatal circuit dysfunction in mental illness may enhance addiction vulnerability. Neonatal ventral hippocampal lesions (NVHL) model this dual diagnosis causality by producing a schizophrenia syndrome with enhanced responsiveness to addictive drugs. Rat genome-wide microarrays containing >24,000 probsets were used to examine separate and co-occurring effects… Continue reading

Antecedents and Consequences of Drug Abuse in Rats Selectively Bred for High and Low Response to Novelty.

Antecedents and consequences of drug abuse in rats selectively bred for high and low response to novelty.

Neuropharmacology. 2013 Apr 29;
Flagel SB, Waselus M, Clinton SM, Watson SJ, Akil H

Human genetic and epidemiological studies provide evidence that… Continue reading

The Role of Galanin System in Modulating Depression, Anxiety, and Addiction-Like Behaviors After Chronic Restraint Stress.

The role of galanin system in modulating depression, anxiety, and addiction-like behaviors after chronic restraint stress.

Neuroscience. 2013 Apr 29;
Zhao X, Seese RR, Yun K, Peng T, Wang Z

There is high comorbidity between stress-related psychiatric disorders and… Continue reading

KCNQ Channels Regulate Age-Related Memory Impairment.

KCNQ Channels Regulate Age-Related Memory Impairment.

PLoS One. 2013; 8(4): e62445
Cavaliere S, Malik BR, Hodge JJ

In humans KCNQ2/3 heteromeric channels form an M-current that acts as a brake on neuronal excitability, with mutations causing a form of… Continue reading

Treatment-Enhanced Paired Action Contributes Substantially to Change Across Multiple Health Behaviors: Secondary Analyses of Five Randomized Trials.

Treatment-enhanced paired action contributes substantially to change across multiple health behaviors: secondary analyses of five randomized trials.

Transl Behav Med. 2013 Mar 1; 3(1): 62-71
Yin HQ, Prochaska JO, Rossi JS, Redding CA, Paiva AL, Blissmer B, Velicer WF,… Continue reading

Hepatitis C Treatment for Multimorbid Patients With Substance Use Disorder in a Primary Care-Based Integrated Treatment Centre: A Retrospective Analysis.

Hepatitis C treatment for multimorbid patients with substance use disorder in a primary care-based integrated treatment centre: a retrospective analysis.

Eur J Gastroenterol Hepatol. 2013 Apr 8;
Brunner N, Senn O, Rosemann T, Falcato L, Bruggmann P

OBJECTIVES/BACKGROUND: The… Continue reading

Dependence Is Not Addiction and “tolerance” Declares Addiction.

Dependence is not addiction and “tolerance” declares addiction.

JAMA Intern Med. 2013 Apr 8; 173(7): 595-6
Geller AS

HubMed – addiction

 

Acute ketamine-induced neuroplasticity: ribosomal protein S6 phosphorylation expression in drug addiction-related rat brain areas.

Neuroreport. 2013… Continue reading

Stress as a Common Risk Factor for Obesity and Addiction.

Stress as a Common Risk Factor for Obesity and Addiction.

Biol Psychiatry. 2013 Mar 26;
Sinha R, Jastreboff AM

Stress is associated with obesity, and the neurobiology of stress overlaps significantly with that of appetite and energy regulation. This… Continue reading

An Orexin Hotspot in Ventral Pallidum Amplifies Hedonic ‘liking’ for Sweetness.

An orexin hotspot in ventral pallidum amplifies hedonic ‘liking’ for sweetness.

Neuropsychopharmacology. 2013 Mar 5;
Ho CY, Berridge KC

Orexin (hypocretin) is implicated in stimulating appetite as well as arousal, and in both food reward and drug reward. The… Continue reading

Addiction Rehab: The Selective Dopamine ?-Hydroxylase Inhibitor Nepicastat Attenuates Multiple Aspects of Cocaine-Seeking Behavior.

The Selective Dopamine ?-Hydroxylase Inhibitor Nepicastat Attenuates Multiple Aspects of Cocaine-Seeking Behavior.

Filed under: Addiction Rehab

Neuropsychopharmacology. 2013 Jan 3;
Schroeder JP, Alisha Epps S, Grice TW, Weinshenker D

Although norepinephrine (NE) does not typically modulate cocaine self-administration under… Continue reading