PROFILEing Idiopathic Pulmonary Fibrosis: Rethinking Biomarker Discovery.
PROFILEing idiopathic pulmonary fibrosis: rethinking biomarker discovery.
Eur Respir Rev. 2013 Jun 1; 22(128): 148-152
Maher TM
Despite major advances in the understanding of the pathogenesis of idiopathic pulmonary fibrosis (IPF), diagnosis and management of the condition continue to… Continue reading
Beyond Anti-VEGF: Dual-Targeting Antiangiogenic and Antiproliferative Therapy.
Beyond anti-VEGF: dual-targeting antiangiogenic and antiproliferative therapy.
Am J Transl Res. 2013; 5(4): 393-403
Chen CT, Hung MC
Antiangiogenesis is a promising antitumor strategy that inhibits tumor vascular formation to suppress tumor growth. Specifically, targeting VEGF has shown therapeutic… Continue reading
Hedonic and Behavioral Deficits Associated With Apathy in Parkinson’s Disease: Potential Treatment Implications.
Hedonic and behavioral deficits associated with apathy in Parkinson’s disease: Potential treatment implications.
Mov Disord. 2013 May 27;
Jordan LL, Zahodne LB, Okun MS, Bowers D
BACKGROUND: Many individuals with Parkinson’s disease (PD) experience apathy independent of depression. METHODS:… Continue reading
Propecia Lawsuits: The Lasting Effects of Delayed Drug Warnings.
Propecia lawsuits: the lasting effects of delayed drug warnings.
CMAJ. 2013 May 27;
Collier R
Luminescent complexes of terbium ion for molecular recognition of ibuprofen.
Luminescence. 2013 May 27;
Selivanova N, Vasilieva K, Galyametdinov… Continue reading
Visual Outcome of Cataract in Pediatric Age Group: Does Etiology Have a Role.
Visual outcome of cataract in pediatric age group: does etiology have a role.
Eur J Ophthalmol. 2013 May 13; 0
Shah MA, Shah SM, Shah AH, Pandya JS
Objective: To compare visual outcome results among traumatic and nontraumatic groups… Continue reading
MORECare Research Methods Guidance Development: Recommendations for Ethical Issues in Palliative and End-of-Life Care Research.
MORECare research methods guidance development: Recommendations for ethical issues in palliative and end-of-life care research.
Palliat Med. 2013 May 21;
Gysels M, Evans CJ, Lewis P, Speck P, Benalia H, Preston NJ, Grande GE, Short V, Owen-Jones E, Todd… Continue reading
Publication Bias, With a Focus on Psychiatry: Causes and Solutions.
Publication Bias, with a Focus on Psychiatry: Causes and Solutions.
CNS Drugs. 2013 May 22;
Turner EH
Publication bias undermines the integrity of the evidence base by inflating apparent drug efficacy and minimizing drug harms, thus skewing the risk-benefit… Continue reading
The Efficacy of Multimodal High-Volume Wound Infiltration in Primary Total Knee Replacement in Facilitating Immediate Post-Operative Pain Relief and Attainment of Early Rehabilitation Milestones.
The efficacy of multimodal high-volume wound infiltration in primary total knee replacement in facilitating immediate post-operative pain relief and attainment of early rehabilitation milestones.
Eur J Orthop Surg Traumatol. 2013 May 21;
Banerjee P
Inadequate pain relief after lower… Continue reading
Tumor Burden Talks in Cancer Treatment With PEGylated Liposomal Drugs.
Tumor Burden Talks in Cancer Treatment with PEGylated Liposomal Drugs.
PLoS One. 2013; 8(5): e63078
Lin YY, Kao HW, Li JJ, Hwang JJ, Tseng YL, Lin WJ, Lin MH, Ting G, Wang HE
PEGylated liposomes are important drug carriers that can passively target tumor by enhanced permeability and retention (EPR) effect in neoplasm lesions. This study demonstrated that tumor burden determines the tumor uptake, and also the tumor response, in cancer treatment with PEGylated liposomal drugs in a C26/tk-luc colon carcinoma-bearing mouse model.Empty PEGylated liposomes (NanoX) and those encapsulated with VNB (NanoVNB) were labeled with In-111 to obtain InNanoX and InVNBL in high labeling yield and radiochemical purity (all >90%). BALB/c mice bearing either small… Continue reading