Synergistic Effects of Low-Level Laser and Mesenchymal Stem Cells on Functional Recovery in Rats With Crushed Sciatic Nerves.

Synergistic effects of low-level laser and mesenchymal stem cells on functional recovery in rats with crushed sciatic nerves.

J Tissue Eng Regen Med. 2013 Mar 7;
Yang CC, Wang J, Chen SC, Hsieh YL

Transplantation of mesenchymal stem cells (MSCs) has been proposed to exert beneficial effects on peripheral nerve regeneration after a peripheral nerve injury, but the functional recovery in the denervated limb is still limited. In this study, we used low-level laser therapy (LLLT) as an adjunct therapy for MSC transplantation on the functional recovery of crushed sciatic nerve in rats. Peripheral nerve injury was induced in 48 Sprague-Dawley rats by crushing the unilateral sciatic nerve, using a vessel clamp. The animals with crushed injury were randomly divided into four groups: control group, with no treatment; MSC group, treated with MSC alone; LLLT group, treated with LLLT alone; and MSCLLLT group, treated with a combination of MSC and LLLT. The sciatic function index (SFI), vertical activity of locomotion (VA) and ankle angle (AA) of rats were examined for functional assessments after treatment. Electrophysiological, morphological and S100 immunohistochemical studies were also conducted. The MSCLLLT group showed a greater recovery in SFI, VA and AA, with significant difference from MSC, LLLT and control groups (p?HubMed – rehab


[Development of Practice Guidelines for Psychological Interventions in the Rehabilitation of Patients with Chronic Low Back Pain: Methods and Results.]

Gesundheitswesen. 2013 Mar 6;
Reese C, Mittag O

The aim of this study was to develop evidence- and consensus-based practice guidelines for psychological interventions in the rehabilitation of patients with chronic low back pain.The practice guidelines have been developed systematically in several steps. Experts from scientific departments and rehabilitation centres as well as rehabilitation patients participated in the development of the practice guidelines. In addition, a draft of the practice guidelines was circulated among head psychologists and chief physicians of somatic orthopaedic rehabilitation centres for their comments and approval.The final practice guidelines comprise recommendations regarding systematic screening and diagnostics of psychologically relevant problems. Furthermore, they include suggestions for the organisation of psychological interventions addressing specific problems.The detailed, evidence- and consensus-based practice guidelines offer an orientation for psychological practice in the somatic rehabilitation of patients with chronic low back pain. HubMed – rehab


A comparison of panel designs with routing methods in the multistage test with the partial credit model.

Behav Res Methods. 2013 Mar 7;
Kim J, Chung H, Park R, Dodd BG

In this study, we compared panel designs applied with various routing methods in the multistage test (MST) based on the partial credit model in the context of classification testing. Simulations were performed to compare three routing methods and four panel structures. Conditions of two test lengths and three passing rates were also included. The results showed that, regardless of the routing method used, the same panel structure performed similarly in terms of the precision of the classification decision with the same test length condition. The longer test length produced higher accuracy, whereas the 50 % passing rate yielded the lowest accuracy. Finally, all MST conditions performed well in terms of test security. HubMed – rehab