Over-the-Counter Access to Emergency Contraception Without Age Restriction: An Opinion of the Women’s Health Practice and Research Network of the American College of Clinical Pharmacy.
Over-the-Counter Access to Emergency Contraception without Age Restriction: An Opinion of the Women’s Health Practice and Research Network of the American College of Clinical Pharmacy.
Pharmacotherapy. 2013 Feb 28;
Rafie S, McIntosh J, Gardner DK, Gawronski KM, Karaoui LR, Koepf ER, Lehman KJ, McBane S, Patel-Shori NM
Family planning remains a high priority area for the United States, with goals to increase the proportion of pregnancies that are intended, reduce pregnancy rates among adolescents, and increase contraceptive use prioritized in the Healthy People 2020 objectives. Contraception intended for use after unprotected intercourse, known as emergency contraception, remains underutilized. Levonorgestrel is one method of oral emergency contraception, which prevents fertilization and does not disrupt an already established pregnancy; thus, timing of administration is critical. Despite data demonstrating safety and efficacy, evidence-based decision making has been overshadowed by politically charged actions involving levonorgestrel emergency contraception for over a decade. The Women’s Health Practice and Research Network of the American College of Clinical Pharmacy supports expanded access to levonorgestrel emergency contraception and removal of barriers such as age restrictions on the nonprescription drug product. Pharmacists remain a key provider of emergency contraceptive services and can help ensure timely access. In states where direct pharmacy access to emergency contraception is available, pharmacists are encouraged to participate. Education, research, and advocacy are other important responsibilities for pharmacists in this arena. HubMed – drug
The Effect of Trazodone on Standardized Field Sobriety Tests.
Pharmacotherapy. 2013 Feb 28;
Ip EJ, Bui QV, Barnett MJ, Kazani A, Wright R, Serino MJ, Perry PJ
STUDY OBJECTIVE: To evaluate the effects of a single dose of trazodone on the standardized field sobriety test (SFST). DESIGN: A randomized, double-blinded, repeated-measures study. PARTICIPANTS: Forty-five healthy adult subjects. SETTING: University campus. MEASUREMENTS AND MAIN RESULTS: The SFST consists of the horizontal gaze nystagmus, walk-and-turn, and one-leg stand tests. Subjects were administered a baseline SFST and at 2 hours after the administration of either trazodone 100 mg (30 subjects) or acetaminophen 650 mg (15 subjects). At 2 hours post drug administration, there were no statistical differences in failure rates between the trazodone and acetaminophen groups (53.3% vs 20.0%, p=0.054). However, the trazodone group exhibited more impairment clues within the individual tests of the SFST than the acetaminophen group. CONCLUSIONS: A one-time dose of trazodone 100 mg does not result in an increased SFST failure rate at 2 hours postdosing compared to acetaminophen 650 mg. However, the number of individual impairment clues detected is increased with trazodone. Trazodone 100 mg may cause cognitive driving impairment. HubMed – drug