Exercise Tolerance in Breast Cancer Patients During Radiotherapy After Aerobic Training.

Exercise tolerance in breast cancer patients during radiotherapy after aerobic training.

Contemp Oncol (Pozn). 2013; 17(2): 205-209
Milecki P, Hojan K, Ozga-Majchrzak O, Moli?ska-Glura M

In spite of the introduction of dose constraints based on patient individual assessment techniques for radiation therapy (RT), some side effects from the heart and lungs are observed. Regular physical exercises improve efficiency, which was confirmed in clinical trials. The aim of this study was to evaluate endurance exercise tolerance and the impact of aerobic training (AT) on selected clinical parameters in breast cancer patients during RT.This study involved 46 women with breast cancer who were irradiated using conformal technique (3DCRT) to a total dose of 50 Gray during a 5-week course of RT. In this period 25 patients (group A) simultaneously performed AT, and the rest of the patients, without rehabilitation (group B), undertook irregular physical activity on their own. The exercise tolerance was assessed through the 6-minute walk test (6MWT) using: oxygen saturation (SO2), heart rate (HR), blood pressure (BP), 6-minute walk distance (6MWD) and dyspnea scale.After AT in group A, a statistically significant (p < 0.05) decrease was observed in average diastolic BP before 6MWT and in HR parameters before and after 6MWT (p > 0.05), and 6MWD was increased (p < 0.05). In group B, after RT, an increase (p < 0.05) in HR was observed after the test as well as dyspnea. Oxygen saturation in both groups was not significantly changed.The results of our study showed that regular AT after just 6 weeks caused an improvement in exercise tolerance parameters with a substantial decline in dyspnea in breast cancer patients receiving RT. HubMed – rehab


Effects of Exercise Training on Fatigue in Multiple Sclerosis: A Meta-Analysis.

Psychosom Med. 2013 Jun 20;
Pilutti LA, Greenlee TA, Motl RW, Nickrent MS, Petruzzello SJ

ObjectiveTo provide a quantitative synthesis of randomized controlled trials examining the effect of exercise training on symptomatic fatigue in persons with multiple sclerosis (MS).MethodsElectronic databases (Web of Science, PubMed, PsycInfo, and Google Scholar) were searched for articles published between 1960 and October 2012 by using the key words “fatigue,” OR “tiredness,” OR “energy,” OR “mood,” OR “lassitude,” AND “exercise,” OR “physical activity,” OR “rehabilitation,” OR “fitness” WITH “multiple sclerosis.” The initial search resulted in 311 articles, of which 74 were reviewed in detail and 17 met the inclusion criteria and provided enough data to compute effect sizes (ESs; Cohen d). The meta-analysis was conducted using a meta-analysis software program, and a random-effects model was used to calculate the overall ES, expressed as Hedge g.ResultsThe weighted mean ES from 17 randomized controlled trials with 568 participants with MS was 0.45 (standard error = 0.12, 95% confidence interval = 0.22-0.68, z = 3.88, p ? .001). The weighted mean ES was slightly heterogeneous (Q = 29.9, df = 16, p = .019).ConclusionsThe cumulative evidence supports that exercise training is associated with a significant small reduction in fatigue among persons with MS. HubMed – rehab


Preventive psychiatry: Concept appraisal and future directions.

Int J Soc Psychiatry. 2013 Jun 19;
Trivedi JK, Tripathi A, Dhanasekaran S, Moussaoui D

Preventive psychiatry is a branch of psychiatry that aims at health promotion, protection from specific mental illnesses, early diagnosis, effective treatment, disability limitation and rehabilitation. Prevention of neuropsychiatric illnesses as compared to other illnesses is particularly important as they run a chronic course and cause substantial disability. Preventive measures have been found to be effective in reducing incidence and disability in a wide range of mental illnesses such as depression, psychosis, anxiety and conduct disorders. The need of the hour is to translate advances in our understanding of mental illness into effective intervention programmes for the prevention of mental illness and the promotion of positive mental health. HubMed – rehab