Eating Disorders: Latest Advancements in the Pharmacological Treatment of Binge Eating Disorder.

Latest advancements in the pharmacological treatment of binge eating disorder.

Filed under: Eating Disorders

Eur Rev Med Pharmacol Sci. 2012 Dec; 16(15): 2102-7
Marazziti D, Corsi M, Baroni S, Consoli G, Catena-Dell’osso M

Binge-eating disorder (BED) is a relatively new disorder characterized by binge eating without purging. The purpose of this article is to review the potential use of the recently proposed compounds for the treatment of BED. A medline of published articles from 1980 to December 2012 was carried out using the following keywords: BED and treatment, topiramate, zonisamide, ghrelin. The pharmacological treatment of BED is still heterogenous and poorly established, mainly for the lack of controlled studies in large samples of patients. The data on serotonin and norepinephrine reuptake inhibitors and on novel anticonvulsants seem quite promising in terms of efficacy and tolerability. In addition, the preliminary findings on the possibility of modulating appetite through the interference with the ghrelin system suggest new and intriguing ways of intervention in BED.
HubMed – eating


Eating management and functional outcome of elderly patients with symptomatic ischemic stroke undergoing inpatient rehabilitation.

Filed under: Eating Disorders

Geriatr Gerontol Int. 2012 Dec 21;
Mizrahi EH, Arad M, Weiss A, Leibovitz A, Adunsky A

AIM: The purpose of this study was to investigate whether, and to what extent, post-stroke eating management (EM) at admission to a rehabilitation ward is associated with functional outcome. METHODS: This was a retrospective study comprising 716 consecutive elderly patients with first ever symptomatic ischemic stroke. Level of eating management was determined by Functional Independence Measurement (FIM) subscale scores relevant to eating management, where scores ?5 points define low-eating management (Low-EM) ability and scores >5 indicate independent eating management. Data was analyzed by t-test, ?(2) -test, Pearson’s correlation and by multiple linear regression analysis. RESULTS: A total of 418 and 298 Low-EM and High-EM patients, respectively, were eligible for final analysis. Compared with High-EM, Low-EM patients were slightly older (P?=?0.04), had longer rehabilitation stays (P?HubMed – eating


Seroepidemiology of Helicobacter pylori Infection in a Mennonite Community in Durango State, Mexico.

Filed under: Eating Disorders

Helicobacter. 2012 Dec 20;
Alvarado-Esquivel C

BACKGROUND: The epidemiology of Helicobacter pylori infection among Mennonites (an ethnic group of German descent living in rural communities in Mexico) has not been previously studied. MATERIALS AND METHODS: The prevalence of anti-H. pylori IgG antibodies was examined in 152 Mennonite individuals in Durango State, Mexico, using enzyme-linked immunoassays. Seroprevalence association with sociodemographic, clinical, and behavioral characteristics of the Mennonite community was also investigated. RESULTS: In total, 77 (50.7%) of the 152 Mennonite participants (mean age, 38.4 ± 15.5 years) had H. pylori IgG antibodies, 35 (45.4%) of whom had H. pylori IgG antibody levels higher than 100 U/mL. Males and females had comparable seroprevalence rates of H. pylori and H. pylori IgG antibody levels. On the other hand, seroprevalence of H. pylori increased significantly with age and was significantly higher among women with history of deliveries and abortions than among those with no such obstetric characteristics. Logistic regression analysis of behavioral characteristics showed that H. pylori infection was associated with a low frequency of eating at restaurants and at fast food outlets (up to 10 times/year) (OR = 2.77; 95% CI: 1.28-5.98; p = .009), and eating meat (up to 3 days/week) (OR = 2.84; 95% CI: 1.36-5.91; p = .005). CONCLUSIONS: This is the first report on the seroprevalence of H. pylori among Mennonites, factors contributing to such infection, and the association of H. pylori infection with abortions and low frequencies of eating out of home and meat. Further research should be conducted on this topic.
HubMed – eating


Oropharyngeal dysphagia in amyotrophic lateral sclerosis alters quality of life.

Filed under: Eating Disorders

J Oral Rehabil. 2012 Dec 27;
Paris G, Martinaud O, Petit A, Cuvelier A, Hannequin D, Roppeneck P, Verin E

Dysphagia is one of the most important complications encountered in amyotrophic lateral sclerosis (ALS). Our aim was to determine whether oropharyngeal dysphagia impacted the quality of life (QoL) of patients with ALS. Thirty consecutive patients were recruited (31-82 years, 18 men). Swallowing function was evaluated using a standardised videofluoroscopic barium swallow. All the patients completed a specific questionnaire on quality of life in dysphagia (SWAL-QoL) immediately after the videofluoroscopy. The results of dysphagia outcome severity scale separated 14 patients with oropharyngeal dysphagia and 16 with normal swallowing function. There was no difference in the average age, weight and body mass index of the two groups (dysphagic patients: 68 ± 11 kg versus non-dysphagic patients: 69 ± 14 kg). Most of the dysphagic patients had a bulbar affection based on their Norris scores which determine the importance of cranial nerves illness (20 ± 8), significantly lower than those of the non-dysphagic patients (35 ± 5) (P < 0·0001). There was no difference in the neurological peripheral symptoms evaluated by Amyotrophic Lateral Sclerosis Functional Rating Scale scores (dysphagic patients: 26 ± 7 versus non-dysphagic patients: 27 ± 8) (ns). The swallowing quality of life questionnaire revealed that the dysphagic patients had significant burden (P < 0·001). They were affected by the necessity to applied a food selection (P < 0·01), by the increase in eating duration (P < 0·05) and described a decrease in eating desire (P < 0·05). They complained of fear regarding the risk of dysphagia (P < 0·05). They also described difficulties with oral communication (P < 0·001). All of those complained about dysphagia which impacted directly mental health (P < 0·05) and social life (P < 0·05). In conclusion, oropharyngeal dysphagia is a common symptom accompanying ALS, which alters the patient's QoL, especially social health. HubMed – eating



Part 5 – What should parents do if an eating disorder is recognized? Interview with Jessica Setnick – Like this video? Please click the thumbs up and subscribe to this channel – thanks! Actions to take if an eating disorder is recognized. Last in 5-part series with award-winning international eating disorder expert Jessica Setnick, MS, RD, CEDRD and author of the Pocket Guide to Eating Disorders ( with Jennifer Neily, MS, RD, CSSD, LD (


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