Depression Treatment: Relations Between Pain Characteristics, Child and Parent Variables, and School Functioning in Adolescents With Chronic Headache: A Comparison of Tension-Type Headache and Migraine.

Relations Between Pain Characteristics, Child and Parent Variables, and School Functioning in Adolescents With Chronic Headache: A Comparison of Tension-Type Headache and Migraine.

Filed under: Depression Treatment

J Pediatr Psychol. 2012 Dec 17;
Kaczynski KJ, Claar RL, Lebel AA

OBJECTIVE: To assess for differences in headache characteristics and psychosocial factors based on headache diagnosis, and to evaluate whether headache diagnosis moderates relations between psychosocial factors and school difficulties. METHODS: Retrospective chart review was conducted with 262 adolescents with chronic tension-type headache (TTH; N = 153) and migraine evaluated at a pediatric headache clinic. Adolescents completed measures of anxiety, depression, and pain coping. Parents completed a measure of parental protective behavior and school functioning. RESULTS: Adolescents with TTH reported greater depression symptoms, and their parents endorsed greater school difficulties, whereas parents of adolescents with migraine reported more protective parenting. Protective parenting was positively associated with school difficulties in both groups, but the relation was significantly stronger in adolescents with TTH. Headache duration and depression symptoms were significant predictors of school functioning in both groups. CONCLUSIONS: Headache duration and depression may impact school functioning independent of headache diagnosis. Protective parenting, in particular, seems to be linked to school-related disability in adolescents with TTH, and this link may be important to consider in assessment and treatment.
HubMed – depression


A Case of Atypical Absence Seizures After Electroconvulsive Treatment in a Patient With Treatment-Resistant Depression.

Filed under: Depression Treatment

Clin EEG Neurosci. 2012 Dec 17;
Burakgazi E, Dalkilic A, Moghal U, Shah U, Carran M

Electroconvulsive therapy (ECT) has been used to treat severe treatment-resistant major depressive disorder. Multiple psychotropic medications are usually prescribed in high doses prior to or concomitantly with ECT. Little is known about the interaction of ECT with psychotropic medications. ECT is known to induce seizures, but its tendency to induce absence seizures is not. We present a case of a 44-year-old female, on multiple psychotropic medications, who had frequent atypical absence seizures for many days after ECT. Electroencephalography (EEG) confirmed atypical absence seizures by the presence of typical 2.5 to 3 Hz generalized sharp and slow waves with disorganized background activity.
HubMed – depression


Opioid-induced respiratory depression in paediatrics: a review of case reports.

Filed under: Depression Treatment

Br J Anaesth. 2012 Dec 17;
Niesters M, Overdyk F, Smith T, Aarts L, Dahan A

Opioids remain the cornerstone of modern-day pain treatment, also in the paediatric population. Opioid treatment is potentially life-threatening, although there are no numbers available on the incidence of opioid-induced respiratory depression (OIRD) in paediatrics. To get an indication of specific patterns in the development/causes of OIRD, we searched PubMed (May 2012) for all available case reports on OIRD in paediatrics, including patients 12 yr of age or younger who developed OIRD from an opioid given to them for a medical indication or due to transfer of an opioid from their mother in the perinatal setting, requiring naloxone, tracheal intubation, and/or resuscitation. Twenty-seven cases are described in 24 reports; of which, seven cases were fatal. In eight cases, OIRD was due to an iatrogenic overdose. Three distinct patterns in the remaining data set specifically related to OIRD include: (i) morphine administration in patients with renal impairment, causing accumulation of the active metabolite of morphine; (ii) codeine use in patients with CYP2D6 gene polymorphism associated with the ultra-rapid metabolizer phenotype, causing enhanced production of the morphine; and (iii) opioid use in patients after adenotonsillectomy for recurrent tonsillitis and/or obstructive sleep apnoea, where OIRD may be related to hypoxia-induced enhancement of OIRD. Despite the restrictions of this approach, our analysis does yield an important insight in the development of OIRD, with specific risk factors clearly present in the data.
HubMed – depression



Dr Dave’s weekly Healthy Bastards Health Tip 30/07/2012 – Healthy Bastards health tip 30/07/2012. Depression Part 3


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