Validity and Reliability of the EQ-5D for Cancer Patients in Korea.

Validity and reliability of the EQ-5D for cancer patients in Korea.

Filed under: Depression Treatment

Support Care Cancer. 2012 Apr 10;
Kim SH, Hwang JS, Kim TW, Hong YS, Jo MW

PURPOSE: The purpose of this study was to assess the validity and reliability of the Korean version of the EQ-5D health questionnaire for use in patients with cancer in Korea. METHODS: Patients with colorectal cancer were recruited from one ambulatory cancer center. Each participant consecutively self-administered the EQ-5D, the EORTC QLQ-C30, and the Short Form-36 (SF-36). Discriminatory ability was evaluated by comparing the SF-36 subscales with their corresponding EQ-5D dimensions. Convergent validity was assessed by examining the correlations between the EQ-5D index, EORTC QLQ-C30 subscales, and SF-36 scale and summary scores. Test-retest reliability was also evaluated. RESULTS: Subjects reporting problems in each EQ-5D dimension showed lower scores on all SF-36 subscales. As expected, the relationships were stronger between the EQ-5D functional dimensions and physical function on the EORTC QLQ-C30 and between the EQ-5D anxiety/depression dimension and emotional function on the EORTC QLQ-C30. The EQ-5D index and SF-36 scales were moderately or highly correlated. intraclass correlation coefficient of the EQ-5D index was 0.45. CONCLUSIONS: The Korean version of the EQ-5D may be a valid tool for assessing the health-related quality of life of patients with cancer. However, further research is needed to determine the reliability of the Korean EQ-5D over different time intervals and disease conditions.
HubMed – depression


Eicosapentaenoic acid appears to be the key omega-3 fatty acid component associated with efficacy in major depressive disorder: a critique of Bloch and Hannestad and updated meta-analysis.

Filed under: Depression Treatment

Mol Psychiatry. 2012 Apr 10;
Martins JG, Bentsen H, Puri BK

HubMed – depression


Maternal depression and infant daytime cortisol.

Filed under: Depression Treatment

Dev Psychobiol. 2012 Apr 9;
Azak S, Murison R, Wentzel-Larsen T, Smith L, Gunnar MR

The effect of maternal depressive disorder on infant daytime cortisol production was studied in three groups of infants; one group with mothers with comorbid depression and anxiety (n?=?19), a second group with mothers with depression only (n?=?7), and a third group with non-depressed mothers (n?=?24). The infants’ cortisol production pattern was measured when they were 6, 12, and 18 months old in combination with repeated measures of parenting stress and depression symptoms. Multilevel modeling analyses showed that infants of mothers with comorbid depression and anxiety had relatively higher cortisol production from morning to bedtime and higher bedtime values as compared to infants of non-depressed mothers and infants of depressed only mothers when they were 6 and 12 months old, but not when 18 months old. The results were interpreted in light of possible changes in the infants’ stress regulatory capacities or changes in maternal coping strategies at infant age 18 months. © 2012 Wiley Periodicals, Inc. Dev Psychobiol.
HubMed – depression


Magnetic pulses draw good reviews from doctors treating depression

Filed under: Depression Treatment

When the darkness lifted in Nan Miller's mind, she realized the new therapy for her depression was finally working. Transcranial magnetic therapy, which was approved by the FDA for use with the NeuroStar TMS therapy system in 2008, has been a lifeline …
Read more on Chicago Tribune


Trial Shows Autistic Brooklyn Kid Shocked Repeatedly As 'Treatment'

Filed under: Depression Treatment

The "treatment" at the center has nothing to do with electroconvulsive therapy, where people with severe depression are induced into having seizures under anesthesia — it's behavior modification for troubled children, and the Rotenberg Center is the …
Read more on New York Magazine


Dads: Watch for signs of postpartum depression

Filed under: Depression Treatment

By ROBERT NICKELL Clinically, postpartum depression is a severe depression that can occur in women post-delivery. Treatment, symptoms and reaction time can vary from woman to woman. It can show up anytime within a year after delivery; however, …


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