White matter

Orexin Receptors: Multi-Functional Therapeutic Targets for Sleeping Disorders, Eating Disorders, Drug Addiction, Cancers and Other Physiological Disorders.

Orexin receptors: Multi-functional therapeutic targets for sleeping disorders, eating disorders, drug addiction, cancers and other physiological disorders.

Cell Signal. 2013 Jul 31;
Xu TR, Yang Y, Ward R, Gao L, Liu Y

The orexin peptides (orexin A, orexin B)… Continue reading

The Ascending Reticular Activating System From Pontine Reticular Formation to the Thalamus in the Human Brain.

The ascending reticular activating system from pontine reticular formation to the thalamus in the human brain.

Front Hum Neurosci. 2013; 7: 416
Yeo SS, Chang PH, Jang SH

Introduction: Action of the ascending reticular activating system (ARAS) on the cerebral cortex is responsible for achievement of consciousness. In this study, we attempted to reconstruct the lower single component of the ARAS from the reticular formation (RF) to the thalamus in the normal human brain using diffusion tensor imaging (DTI). Methods: Twenty six normal healthy subjects were recruited for this study. A 1.5-T scanner was used for scanning of diffusion tensor images, and the lower single component of the ARAS was reconstructed using FMRIB software. We utilized two ROIs for reconstruction of the lower single component of the ARAS: the seed ROI – the RF of the pons at the level of the trigeminal nerve entry zone, the target ROI – the intralaminar nuclei of the thalamus at the level of the commissural plane. Results: The reconstructed ARAS originated from the pontine RF, ascended through the mesencephalic tegmentum just posterior to the red nucleus, and then terminated on the intralaminar nuclei of the thalamus. No significant differences in fractional anisotropy, mean diffusivity, and tract number were observed between hemispheres (p?>?0.05). Conclusion: We reconstructed the lower single component of the ARAS… Continue reading

Aesthetic Acceptance Equals to Nature’s Compensation Plus Surgical Correction.

Aesthetic acceptance equals to nature’s compensation plus surgical correction.

BMJ Case Rep. 2013; 2013:
Vadgaonkar V, Gangurde P, Karandikar A, Mahajan N

Orthognathic surgery has become an acceptable treatment plan for patients with various maxillofacial deformities. The rehabilitation of… Continue reading

Mutation in Ribosomal Protein S5 Leads to Spectinomycin Resistance in Neisseria Gonorrhoeae.

Mutation in ribosomal protein S5 leads to spectinomycin resistance in Neisseria gonorrhoeae.

Front Microbiol. 2013; 4: 186
Ilina EN, Malakhova MV, Bodoev IN, Oparina NY, Filimonova AV, Govorun VM

Spectinomycin remains a useful reserve option for therapy of gonorrhea.… Continue reading

Self Harm and Anxiety.


 

Self Harm and Anxiety. – Hey guys, hope this helps c:

 

Could Brain Scans Reveal The Right Treatment For Depression?
The authors of the study, which was published online in JAMA Psychiatry, readily acknowledge that this concept… Continue reading

Aspects of Patient and Clinician Language Predict Adherence to Antidepressant Medication.

Aspects of patient and clinician language predict adherence to antidepressant medication.

J Am Board Fam Med. 2013 Jul-Aug; 26(4): 409-20
Kaplan JE, Keeley RD, Engel M, Emsermann C, Brody D

Objective: High-quality patient-clinician communication is associated with better medication adherence, but the specific language components associated with adherence are poorly understood. We examined how patient and clinician language may influence adherence.We audio-recorded primary care encounters from 63 patients newly diagnosed with depression and prescribed an antidepressant medication. We rated clinicians’ language (motivational interviewing-adherent statements [MIAs], reflections, and global ratings of empathy and “motivational interviewing spirit”) along with patients’ “change talk” (CT) demonstrating motivation to take medication. Filling a first prescription and an estimate of overall adherence, the proportion of >180 days covered (PDC) (primary outcome), were measured based… Continue reading

Decreased Mitochondrial DNA Copy Number in the Hippocampus and Peripheral Blood During Opiate Addiction Is Mediated by Autophagy and Can Be Salvaged by Melatonin.

Decreased mitochondrial DNA copy number in the hippocampus and peripheral blood during opiate addiction is mediated by autophagy and can be salvaged by melatonin.

Autophagy. 2013 Jun 20; 9(9):
Feng YM, Jia YF, Su LY, Wang D, Lv L,… Continue reading

Returning to Work After Long Term Sickness Absence Due to Low Back Pain – the Struggle Within: A Qualitative Study of the Patient’s Experience.

Returning to work after long term sickness absence due to low back pain – the struggle within: A qualitative study of the patient’s experience.

Work. 2013 Jun 20;
Ryan CG, Lauchlan D, Rooney L, Hollins-Martins C, Gray H

Low… Continue reading

Sleep Disturbance Correlates With White Matter Hyperintensity in Patients With Subcortical Ischemic Vascular Dementia.

Sleep Disturbance Correlates With White Matter Hyperintensity in Patients With Subcortical Ischemic Vascular Dementia.

J Geriatr Psychiatry Neurol. 2013 Jun 19;
Cheng CY, Tsai CF, Wang SJ, Hsu CY, Fuh JL

Background:Subcortical ischemic vascular dementia (SIVD) caused by small-artery… Continue reading

Relationships Among Cognition, Emotion, and Motivation: Implications for Intervention and Neuroplasticity in Psychopathology.

Relationships among cognition, emotion, and motivation: implications for intervention and neuroplasticity in psychopathology.

Front Hum Neurosci. 2013; 7: 261
Crocker LD, Heller W, Warren SL, O’Hare AJ, Infantolino ZP, Miller GA

Emotion-cognition and motivation-cognition relationships and related brain mechanisms… Continue reading