Advancement of Imidazo[1,2-a]pyridines With Improved Pharmacokinetics and Nanomolar Activity Against Mycobacterium Tuberculosis.
... the M. marinum group expressed more interleukin (IL)-1B and IL-12p40 on day 3 (IL-1B: P = 0.003 and 0.004, respectively; IL-12p40: P = 0.001 and 0.011, respectively), a higher level of CXCL10 on day 1 (P = 0.006 and… Continue reading
Emerging Role of Calcium-Activated Potassium Channel in the Regulation of Cell Viability Following Potassium Ions Challenge in HEK293 Cells and Pharmacological Modulation.
... P4502E1 activity, cytochrome P4501A1 expression, in addition to sulfotransferase1A1 expression were determined to deduce the effect of BCA on hepatic metabolism. As oxidative stress markers, lipid peroxides levels, reduced glutathione, superoxide dismutase and catalase activities, as well as the… Continue reading
Nanoparticles in the Ocular Drug Delivery.
... This review is concerned with recent findings and applications of NPs drug delivery systems for the treatment of different eye diseases. HubMed – drug Adalimumab (Humira) induced acute lung injury. Am J Case Rep. 2013; 14: 173-5Kohli R,… Continue reading
Nicotine Affects Cutaneous Wound Healing in Stressed Mice.
... were not subjected to stress. These stressed and control animals were treated with a transdermal nicotine patch that was changed every day. A full-thickness excisional lesion was also generated, and 14 days later, lesions had recovered. However, the… Continue reading
Early Neurological Outcome of Young Infants Exposed to Selective Serotonin Reuptake Inhibitors During Pregnancy: Results From the Observational SMOK Study.
... Japan, similar to that in other developed countries where published data exist. Compared with other disorders, such as depression or anxiety disorders, the direct cost accounted for a relatively high proportion of the total cost. Furthermore, absolute costs arising… Continue reading
Protein-Protein Interactions Inferred From Domain-Domain Interactions in Genogroup II Genotype 4 Norovirus Sequences.
... are infected and treated with Withania somnifera (ethanol root extract) with doses 50 and 100?mg/kg. BW, respectively. Gp5 infected treated group was treated with cefoperazone antibiotic at dose 35?mg/Kg BW. The treatment by drug or the extracted medicinal plant… Continue reading
Type of Mask May Impact on Continuous Positive Airway Pressure Adherence in Apneic Patients.
... via Blockade of Presynaptic ?2A-Adrenergic Receptor. PLoS One. 2013; 8(5): e63622Wang Y, Yu X, Wang F, Wang Y, Wang Y, Li H, Lv X, Lu D, Wang H Myocardial depression is an important contributor to mortality in sepsis. We… Continue reading