resistant cells

An Engineering Approach to Biomedical Sciences: Advanced Strategies in Drug Delivery Systems Production.

An engineering approach to biomedical sciences: advanced strategies in drug delivery systems production.

Transl Med UniSa. 2012 Sep; 4: 3-11
Barba AA, Dalmoro A, d’Amore M

Development and optimization of novel production techniques for drug delivery systems are fundamental… Continue reading

Unintentional Weakness of Cancers: The MEK/ERK Pathway as a Double-Edged Sword.

Unintentional weakness of cancers: the MEK/ERK pathway as a double-edged sword.

Mol Cancer Res. 2013 Jul 30;
Suda K, Mitsudomi T

Recent advances in molecular target therapy have greatly improved treatment outcomes for cancers driven by oncogenic mutations. However… Continue reading

Medication-Assisted Treatment of Opiate Dependence Is Gaining Favor.

Medication-assisted treatment of opiate dependence is gaining favor.

Cleve Clin J Med. 2013 Jun; 80(6): 345-9
Jerry JM, Collins GB

People addicted to opiates are more likely to avoid returning to these drugs if they participate in a program… Continue reading

The Effect of Dantonic Pill on ? -Catenin Expression in a Rat Model of Streptozotocin-Induced Early Stage of Diabetic Nephropathy.

The Effect of Dantonic Pill on ? -Catenin Expression in a Rat Model of Streptozotocin-Induced Early Stage of Diabetic Nephropathy.

J Diabetes Res. 2013; 2013: 848679
Shuhong Z, Hongjun L, Bo C, Li X, Bingyin S

Diabetic nephropathy (DN)… Continue reading

Rapid Detection of Human Cytomegalovirus UL97 and UL54 Mutations Directly From Patient Samples.

Rapid Detection of Human Cytomegalovirus UL97 and UL54 Mutations Directly from Patient Samples.

J Clin Microbiol. 2013 May 15;
Sedlak RH, Castor J, Butler-Wu SM, Chan E, Cook L, Limaye AP, Jerome KR

Human cytomegalovirus (CMV) is a significant… Continue reading

Noninvasive Visualization of MicroRNA-16 in the Chemoresistance of Gastric Cancer Using a Dual Reporter Gene Imaging System.

Noninvasive Visualization of MicroRNA-16 in the Chemoresistance of Gastric Cancer Using a Dual Reporter Gene Imaging System.

PLoS One. 2013; 8(4): e61792
Wang F, Song X, Li X, Xin J, Wang S, Yang W, Wang J, Wu K, Chen… Continue reading

Luteolin Is a Novel P90 Ribosomal S6 Kinase (RSK) Inhibitor That Suppresses Notch4 Signaling by Blocking the Activation of Y-Box Binding Protein-1 (YB-1).

Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1).

Oncotarget. 2013 Feb; 4(2): 329-45
Reipas KM, Law JH, Couto N, Islam S, Li Y, Li… Continue reading

Excessive MET Signaling Causes Acquired Resistance and Addiction to MET Inhibitors in the MKN45 Gastric Cancer Cell Line.

Excessive MET signaling causes acquired resistance and addiction to MET inhibitors in the MKN45 gastric cancer cell line.

Invest New Drugs. 2013 Apr 9;
Funakoshi Y, Mukohara T, Tomioka H, Ekyalongo RC, Kataoka Y, Inui Y, Kawamori Y, Toyoda… Continue reading

Two 4N Cell-Cycle Arrests Contribute to Cisplatin-Resistance.

Two 4N Cell-Cycle Arrests Contribute to Cisplatin-Resistance.

PLoS One. 2013; 8(4): e59848
Shen H, Perez RE, Davaadelger B, Maki CG

Cisplatin is a platinum-based drug that is used for the treatment of a wide-variety of primary human cancers. However,… Continue reading

Label-Free Recognition of Drug Resistance via Impedimetric Screening of Breast Cancer Cells.

Label-Free Recognition of Drug Resistance via Impedimetric Screening of Breast Cancer Cells.

PLoS One. 2013; 8(3): e57423
Eker B, Meissner R, Bertsch A, Mehta K, Renaud P

We present a novel study on label-free recognition and distinction of drug… Continue reading