NMDA receptor

Cerecor Initiates Phase II Trial of CERC-301 to Treat Major Depressive …

Cerecor initiates Phase II trial of CERC-301 to treat major depressive …
The company's oral, selective NMDA receptor subunit 2B (NR2B) antagonist CERC-301is indicated for the adjunctive treatment of subjects with major depressive disorder (MDD) who have not adequately responded… Continue reading →

Sensitivity to Theta-Burst Timing Permits LTP in Dorsal Striatal Adult Brain Slice.

Sensitivity to theta-burst timing permits LTP in dorsal striatal adult brain slice.

J Neurophysiol. 2013 Aug 7;
Hawes SL, Gillani F, Evans RC, Benkert EA, Blackwell KT

Long term potentiation (LTP) of excitatory afferents to the dorsal striatum likely… Continue reading →

PICK1 Interacts With PACSIN to Regulate AMPA Receptor Internalization and Cerebellar Long-Term Depression.

PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression.

Proc Natl Acad Sci U S A. 2013 Aug 5;
Anggono V, Koç-Schmitz Y, Widagdo J, Kormann J, Quan A, Chen CM, Robinson PJ, Choi SY,… Continue reading →

Use of Conventional and Novel Smokeless Tobacco Products Among US Adolescents.

Use of Conventional and Novel Smokeless Tobacco Products Among US Adolescents.

Pediatrics. 2013 Aug 5;
Agaku IT, Ayo-Yusuf OA, Vardavas CI, Alpert HR, Connolly GN

OBJECTIVES:To assess the prevalence and correlates of use of conventional and novel smokeless tobacco… Continue reading →

Anandamide, Cannabinoid Type 1 Receptor, and NMDA Receptor Activation Mediate Non-Hebbian Presynaptically Expressed Long-Term Depression at the First Central Synapse for Visceral Afferent Fibers.

Anandamide, Cannabinoid Type 1 Receptor, and NMDA Receptor Activation Mediate Non-Hebbian Presynaptically Expressed Long-Term Depression at the First Central Synapse for Visceral Afferent Fibers.

J Neurosci. 2013 Jul 31; 33(31): 12627-37
Khlaifia A, Farah H, Gackiere F, Tell F… Continue reading →

The Antibiotic Susceptibility Patterns of Uropathogenic Escherichia Coli, With Special Reference to the Fluoroquinolones.

The antibiotic susceptibility patterns of uropathogenic Escherichia coli, with special reference to the fluoroquinolones.

J Clin Diagn Res. 2013 Jun; 7(6): 1027-30
Shariff V A AR, Shenoy M S, Yadav T, M R

Context: The emergence of drug resistance… Continue reading →

Multidrug-Resistant Tuberculosis in Panama Is Driven by Clonal Expansion of an MDR-TB Strain Related to the KZN XDR-TB Strain From South Africa.

Multidrug-resistant tuberculosis in Panama is driven by clonal expansion of an MDR-TB strain related to the KZN XDR-TB strain from South Africa.

J Clin Microbiol. 2013 Jul 24;
Lanzas F, Karakousis PC, Sacchettini JC, Ioerger TR

Multidrug-resistant tuberculosis (MDR-TB)… Continue reading →

Bringing Life Course Home: A Pilot to Reduce Pregnancy Risk Through Housing Access and Family Support.

Bringing Life Course Home: A Pilot to Reduce Pregnancy Risk Through Housing Access and Family Support.

Matern Child Health J. 2013 Jul 3;
Allen D, Feinberg E, Mitchell H

Proponents of life course comment that while the theory is… Continue reading →

Effects of Chronic D-Serine Elevation on Animal Models of Depression and Anxiety-Related Behavior.

Effects of Chronic D-Serine Elevation on Animal Models of Depression and Anxiety-Related Behavior.

PLoS One. 2013; 8(6): e67131
Otte DM, Barcena de Arellano ML, Bilkei-Gorzo A, Albayram O, Imbeault S, Jeung H, Alferink J, Zimmer A

NMDA receptors are… Continue reading →

A? Induces Astrocytic Glutamate Release, Extrasynaptic NMDA Receptor Activation, and Synaptic Loss.

A? induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss.

Proc Natl Acad Sci U S A. 2013 Jun 17;
Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto SI, Dziewczapolski G, Nakamura T, Cao… Continue reading →