NMDA receptor

Cerecor Initiates Phase II Trial of CERC-301 to Treat Major Depressive

Cerecor initiates Phase II trial of CERC-301 to treat major depressive
The company's oral, selective NMDA receptor subunit 2B (NR2B) antagonist CERC-301is indicated for the adjunctive treatment of subjects with major depressive disorder (MDD) who have not adequately responded… Continue reading

Sensitivity to Theta-Burst Timing Permits LTP in Dorsal Striatal Adult Brain Slice.

Sensitivity to theta-burst timing permits LTP in dorsal striatal adult brain slice.

J Neurophysiol. 2013 Aug 7;
Hawes SL, Gillani F, Evans RC, Benkert EA, Blackwell KT

Long term potentiation (LTP) of excitatory afferents to the dorsal striatum likely… Continue reading

PICK1 Interacts With PACSIN to Regulate AMPA Receptor Internalization and Cerebellar Long-Term Depression.

PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression.

Proc Natl Acad Sci U S A. 2013 Aug 5;
Anggono V, Koç-Schmitz Y, Widagdo J, Kormann J, Quan A, Chen CM, Robinson PJ, Choi SY,… Continue reading

Use of Conventional and Novel Smokeless Tobacco Products Among US Adolescents.

Use of Conventional and Novel Smokeless Tobacco Products Among US Adolescents.

Pediatrics. 2013 Aug 5;
Agaku IT, Ayo-Yusuf OA, Vardavas CI, Alpert HR, Connolly GN

OBJECTIVES:To assess the prevalence and correlates of use of conventional and novel smokeless tobacco… Continue reading

Anandamide, Cannabinoid Type 1 Receptor, and NMDA Receptor Activation Mediate Non-Hebbian Presynaptically Expressed Long-Term Depression at the First Central Synapse for Visceral Afferent Fibers.

Anandamide, Cannabinoid Type 1 Receptor, and NMDA Receptor Activation Mediate Non-Hebbian Presynaptically Expressed Long-Term Depression at the First Central Synapse for Visceral Afferent Fibers.

J Neurosci. 2013 Jul 31; 33(31): 12627-37
Khlaifia A, Farah H, Gackiere F, Tell F… Continue reading

The Antibiotic Susceptibility Patterns of Uropathogenic Escherichia Coli, With Special Reference to the Fluoroquinolones.

The antibiotic susceptibility patterns of uropathogenic Escherichia coli, with special reference to the fluoroquinolones.

J Clin Diagn Res. 2013 Jun; 7(6): 1027-30
Shariff V A AR, Shenoy M S, Yadav T, M R

Context: The emergence of drug resistance… Continue reading

Multidrug-Resistant Tuberculosis in Panama Is Driven by Clonal Expansion of an MDR-TB Strain Related to the KZN XDR-TB Strain From South Africa.

Multidrug-resistant tuberculosis in Panama is driven by clonal expansion of an MDR-TB strain related to the KZN XDR-TB strain from South Africa.

J Clin Microbiol. 2013 Jul 24;
Lanzas F, Karakousis PC, Sacchettini JC, Ioerger TR

Multidrug-resistant tuberculosis (MDR-TB)… Continue reading

Bringing Life Course Home: A Pilot to Reduce Pregnancy Risk Through Housing Access and Family Support.

Bringing Life Course Home: A Pilot to Reduce Pregnancy Risk Through Housing Access and Family Support.

Matern Child Health J. 2013 Jul 3;
Allen D, Feinberg E, Mitchell H

Proponents of life course comment that while the theory is… Continue reading

Effects of Chronic D-Serine Elevation on Animal Models of Depression and Anxiety-Related Behavior.

Effects of Chronic D-Serine Elevation on Animal Models of Depression and Anxiety-Related Behavior.

PLoS One. 2013; 8(6): e67131
Otte DM, Barcena de Arellano ML, Bilkei-Gorzo A, Albayram O, Imbeault S, Jeung H, Alferink J, Zimmer A

NMDA receptors are… Continue reading

A? Induces Astrocytic Glutamate Release, Extrasynaptic NMDA Receptor Activation, and Synaptic Loss.

A? induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss.

Proc Natl Acad Sci U S A. 2013 Jun 17;
Talantova M, Sanz-Blasco S, Zhang X, Xia P, Akhtar MW, Okamoto SI, Dziewczapolski G, Nakamura T, Cao… Continue reading