Multiple drug resistance

Anthracycline Nano-Delivery Systems to Overcome Multiple Drug Resistance: A Comprehensive Review.

Anthracycline Nano-Delivery Systems to Overcome Multiple Drug Resistance: A Comprehensive Review.

Nano Today. 2013 Jun 1; 8(3): 313-331
Ma P, Mumper RJ

Anthracyclines (doxorubicin, daunorubicin, and idarubicin) are very effective chemotherapeutic drugs to treat many cancers; however, the development… Continue reading

The Antimicrobial Effect of Lactobacillus Casei Culture Supernatant Against Multiple Drug Resistant Clinical Isolates of Shigella Sonnei and Shigella Flexneri in Vitro.

The antimicrobial effect of lactobacillus casei culture supernatant against multiple drug resistant clinical isolates of Shigella sonnei and Shigella flexneri in vitro.

Iran Red Crescent Med J. 2013 Feb; 15(2): 122-6
Mirnejad R, Vahdati AR, Rashidiani J, Erfani M,… Continue reading

Metabolism and Pharmacokinetics of the Anti-Tuberculosis Drug Ethionamide in a Flavin-Containing Monooxygenase Null Mouse.

Metabolism and Pharmacokinetics of the Anti-Tuberculosis Drug Ethionamide in a Flavin-Containing Monooxygenase Null Mouse.

Pharmaceuticals (Basel). 2012 Nov 1; 5(11): 1147-1159
Palmer AL, Leykam VL, Larkin A, Krueger SK, Phillips IR, Shephard EA, Williams DE

Multiple drug resistance (MDR)… Continue reading

Correction of Drug-Induced Hepatotoxicity With New Triterpene Derivatives in Transplanted RLS Lymphoma.

Correction of Drug-Induced Hepatotoxicity with New Triterpene Derivatives in Transplanted RLS Lymphoma.

Bull Exp Biol Med. 2012 Dec; 154(3): 370-374
Zhukova NA, Semenov DE, Bessergeneva EP, Sorokina IV, Tolstikova TG

The hepatoprotective effects of new triterpene derivatives, betulin 3?,28-di-O-nicotinate… Continue reading

Gemcitabine Plus Erlotinib for Advanced Pancreatic Cancer: A Systematic Review With Meta-Analysis.

Gemcitabine plus erlotinib for advanced pancreatic cancer: a systematic review with meta-analysis.

PLoS One. 2013; 8(3): e57528
Yang ZY, Yuan JQ, Di MY, Zheng DY, Chen JZ, Ding H, Wu XY, Huang YF, Mao C, Tang JL

BACKGROUND: This… Continue reading

Gynostemma Pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients.

Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients.

J Nutr Metab. 2013; 2013: 765383
Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG

Aims. To evaluate the effect of the traditional Vietnamese herb Gynostemma pentaphyllum… Continue reading

Drug and Alcohol Rehabilitation: In Vivo Cell Reprogramming Towards Pluripotency by Virus-Free Overexpression of Defined Factors.

In Vivo Cell Reprogramming towards Pluripotency by Virus-Free Overexpression of Defined Factors.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2013; 8(1): e54754
Yilmazer A, de Lázaro I, Bussy C, Kostarelos K

The ability to induce the reprogramming of… Continue reading

Drug and Alcohol Rehabilitation: A Study on Prescribing Patterns of Antihypertensives in Geriatric Patients.

A study on prescribing patterns of antihypertensives in geriatric patients.

Filed under: Drug and Alcohol Rehabilitation

Perspect Clin Res. 2012 Oct; 3(4): 139-42
Mohd AH, Mateti UV, Konuru V, Parmar MY, Kunduru BR

Hypertension is a leading contributor to… Continue reading

Drug and Alcohol Rehabilitation: Effects of Intracuff Dexamethasone on Post-Extubation Reactions.

Effects of intracuff dexamethasone on post-extubation reactions.

Filed under: Drug and Alcohol Rehabilitation

J Res Med Sci. 2012 Apr; 17(4): 338-43
Rafiei MR, Arianpour N, Rezvani M, Ebrahimi A

The most common complications after tracheal intubation during general anesthesia are sore throat, hoarseness, and laryngospasm which can cause severe discomfort to patients. Several methods have been suggested to prevent these complications. In this study, the effects of intracuff dexamethasone, lidocaine, and normal saline in reducing post-extubation reactions were compared.This double-blind clinical trial was performed on 180 men of ASA (American Society of Anesthesiologists) class I or II who underwent general anesthesia for elective inguinal herniation surgery in Imam Reza Hospital, Tehran, Iran during 2008-2010. Depending on the kind of drug used to fill the endotracheal tube (ETT) cuff, patients were randomly allocated into normal saline, lidocaine, and dexamethasone groups. Post-extubation reactions were then evaluated in all groups.The groups were demographically comparable. There were no significant differences between the three groups regarding post-extubation sore throat, hoarseness, or laryngospasm (p > 0.05). However, a significant difference in cough existed between the… Continue reading