Susceptibility Genes Are Enriched in Those of the HSV-1/host Interactome in Psychiatric and Neurological Disorders.
Susceptibility genes are enriched in those of the HSV-1/host interactome in psychiatric and neurological disorders.
Pathog Dis. 2013 Aug 3;
Carter CJ
Herpes simplex (HSV-1) can promote beta-amyloid deposition and tau phosphorylation, demyelination or cognitive deficits relevant to Alzheimer’s disease or multiple sclerosis and to many neuropsychiatric disorders with which it has been implicated. A seroprevalence much higher than disease incidence has called into question any primary causal role. However, as also the case with risk promoting polymorphisms, (also present in control populations) any causal effects are likely to be conditional. During its life cycle, the virus binds to many proteins and modifies the expression of multiple genes creating a host/pathogen interactome involving 1347 host genes. This dataset is heavily enriched in the susceptibility genes for multiple sclerosis (P= 1.3E-99) >Alzheimer’s disease > schizophrenia > Parkinsonism > depression> bipolar disorder> childhood obesity> chronic fatigue> autism > and anorexia (P=0.047) but not ADHD, a relationship maintained for GWAS datasets in multiple sclerosis and Alzheimer’s… Continue reading
Use of Micronutrients Attenuates Cannabis and Nicotine Abuse as Evidenced From a Reversal Design: A Case Study.
Use of micronutrients attenuates cannabis and nicotine abuse as evidenced from a reversal design: a case study.
J Psychoactive Drugs. 2013 Apr-Jun; 45(2): 168-78
Harrison R, Rucklidge JJ, Blampied N
Prior research shows that micronutrients, particularly amino acids, can… Continue reading
[Subtitled] Part 1: Stephen Fry the Secret Life of the Manic Depressive
[subtitled] Part 1: Stephen Fry The Secret Life Of The Manic Depressive
Note: fr and se subtitles in progress Manic Depression is a disease that’s little talked about and little understood. This programme, presented by Stephen Fr…
Affective… Continue reading
Malibu Alcohol Rehab – California
Malibu Alcohol Rehab – California
Receive Drug and Alcohol Addiction Treatment at www.CliffsideMalibu.com in Malibu, California. Please call for exclusive, professional help at: 800-501-1988….
Corn on the cob: Tips for buying, storing and eating the beloved summer veggie… Continue reading
Couples-Counseling-Therapy-Retreat-Pembroke Pines
Couples-Counseling-Therapy-Retreat-Pembroke Pines
Couples-Counseling-Therapy-Retreat-Pembroke Pines http://www.jenniferspinner.com (305) 409-0099 http://www.goodtherapy.org/jennifer-spinner-therapist.php htt…
Saunders: Those who've received help now hope to help others, too
She plans to become a counselor. “I've been helped much over the years through counseling because of the… Continue reading
The Size, Burden and Cost of Disorders of the Brain in the UK.
The size, burden and cost of disorders of the brain in the UK.
J Psychopharmacol. 2013 Jul 24;
Fineberg NA, Haddad PM, Carpenter L, Gannon B, Sharpe R, Young AH, Joyce E, Rowe J, Wellsted D, Nutt D, Sahakian… Continue reading
SLC1 Glutamate Transporters and Diseases: Psychiatric Diseases and Pathological Pain.
SLC1 Glutamate Transporters and Diseases: Psychiatric Diseases and Pathological Pain.
Curr Mol Pharmacol. 2013 Jul 22;
Nakagawa T, Kaneko S
The solute carrier family 1 (SLC1) consists of two neutral amino acid transporters and five high-affinity excitatory amino acid… Continue reading
Health Professionals Working With First Nations, Inuit, and Métis Consensus Guideline.
Health professionals working with first nations, inuit, and métis consensus guideline.
J Obstet Gynaecol Can. 2013 Jun; 35(6): 550-3
Wilson D, de la Ronde S, Brascoupé S, Apale AN, Barney L, Guthrie B, Harrold E, Horn O, Johnson R,… Continue reading