Smith-Magenis Syndrome: Little Boy From Hawarden Has Come a Long Way
Smith-Magenis syndrome: Little boy from Hawarden has come a long way
“It's fantastic, he's come such a long way. It's lovely to see him eating a slice of pizza like a normal child.” As well as the challenges around food,… Continue reading
New WHO Treatment Guide for Mental Health Trauma
New WHO Treatment Guide for Mental Health Trauma
This is the first time the World Health Organization has issued guidelines dealing with the mental health consequences of trauma and loss. Five years ago, WHO published guidelines for the treatment of… Continue reading
Sensitivity to Theta-Burst Timing Permits LTP in Dorsal Striatal Adult Brain Slice.
Sensitivity to theta-burst timing permits LTP in dorsal striatal adult brain slice.
J Neurophysiol. 2013 Aug 7;
Hawes SL, Gillani F, Evans RC, Benkert EA, Blackwell KT
Long term potentiation (LTP) of excitatory afferents to the dorsal striatum likely… Continue reading
Cocaine Addiction Treatment and Home Remedies: Use of the Scopolamine Transdermal Patch.
Cocaine Addiction Treatment and Home Remedies: Use of the Scopolamine Transdermal Patch.
Subst Use Misuse. 2013 Aug 7;
Gambelunghe C, Bacci M, Aroni K, De Falco F, Ayroldi EM
Recently, there has been an enormous increase in the number… Continue reading
Dopamine Neurons Are Multi-Neurotransmitter Neurons.
Dopamine neurons are multi-neurotransmitter neurons.
Mov Disord. 2013 Aug 7;
Benoit-Marand M
Naltrexone may block euphoria-like placebo effect.
BMJ Case Rep. 2013; 2013:
Samokhvalov AV, Gamaleddin I, Sproule B, Rehm J
Naltrexone is a first-line… Continue reading
Michaud: Closing of Sagamore Is Bad News for LI's Most Troubled Kids
Michaud: Closing of Sagamore is bad news for LI's most troubled kids
In a decision that seems as ill-timed as possible, the state Office of Mental Health announced last month that it will close its only inpatient children's psychiatric program… Continue reading
PICK1 Interacts With PACSIN to Regulate AMPA Receptor Internalization and Cerebellar Long-Term Depression.
PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression.
Proc Natl Acad Sci U S A. 2013 Aug 5;
Anggono V, Koç-Schmitz Y, Widagdo J, Kormann J, Quan A, Chen CM, Robinson PJ, Choi SY,… Continue reading
Blacks Feeling Less Stigmatized in Seeking Mental Health Treatment
Blacks feeling less stigmatized in seeking mental health treatment
But for many blacks, the topic has carried particularly negative connotations — to the point where it's easier to talk about drug or alcohol addiction than depression or anxiety. In 2008,… Continue reading
Susceptibility Genes Are Enriched in Those of the HSV-1/host Interactome in Psychiatric and Neurological Disorders.
Susceptibility genes are enriched in those of the HSV-1/host interactome in psychiatric and neurological disorders.
Pathog Dis. 2013 Aug 3;
Carter CJ
Herpes simplex (HSV-1) can promote beta-amyloid deposition and tau phosphorylation, demyelination or cognitive deficits relevant to Alzheimer’s disease or multiple sclerosis and to many neuropsychiatric disorders with which it has been implicated. A seroprevalence much higher than disease incidence has called into question any primary causal role. However, as also the case with risk promoting polymorphisms, (also present in control populations) any causal effects are likely to be conditional. During its life cycle, the virus binds to many proteins and modifies the expression of multiple genes creating a host/pathogen interactome involving 1347 host genes. This dataset is heavily enriched in the susceptibility genes for multiple sclerosis (P= 1.3E-99) >Alzheimer’s disease > schizophrenia > Parkinsonism > depression> bipolar disorder> childhood obesity> chronic fatigue> autism > and anorexia (P=0.047) but not ADHD, a relationship maintained for GWAS datasets in multiple sclerosis and Alzheimer’s… Continue reading