lung cancer

Effects of Ginger and Expectations on Symptoms of Nausea in a Balanced Placebo Design.

Effects of Ginger and Expectations on Symptoms of Nausea in a Balanced Placebo Design.

Filed under: Drug and Alcohol Rehabilitation

PLoS One. 2012; 7(11): e49031
Weimer K, Schulte J, Maichle A, Muth ER, Scisco JL, Horing B, Enck P,… Continue reading

Tumor Dormancy, Oncogene Addiction, Cellular Senescence, and Self-Renewal Programs.

Tumor Dormancy, Oncogene Addiction, Cellular Senescence, and Self-Renewal Programs.

Filed under: Addiction Rehab

Adv Exp Med Biol. 2013; 734: 91-107
Bellovin DI, Das B, Felsher DW

Cancers are frequently addicted to initiating oncogenes that elicit aberrant cellular proliferation, self-renewal,… Continue reading

Cytoskeletal and Extracellular Matrix Alterations in Limb Girdle Muscular Dystrophy 2I Muscle Fibers.

Cytoskeletal and extracellular matrix alterations in limb girdle muscular dystrophy 2I muscle fibers.

Filed under: Rehab Centers

Neurol India. 2012 Sep-Oct; 60(5): 510-1
Sabatelli P, Pellegrini C, Faldini C, Merlini L

In this detailed muscle biopsy study of a… Continue reading

Low Admission Norton Scale Scores Are Associated With Falls Long After Rehabilitation in the Elderly With Hip Fractures.

Low admission Norton scale scores are associated with falls long after rehabilitation in the elderly with hip fractures.

Filed under: Rehab Centers

Clin Interv Aging. 2012; 7: 431-6
Halperin E, Engel T, Sherman S, Justo D

In this study,… Continue reading

Drug and Alcohol Rehabilitation: Diagnosing and Treating Opioid Dependence.

Diagnosing and treating opioid dependence.

Filed under: Drug and Alcohol Rehabilitation

J Fam Pract. 2012 Oct; 61(10): 588-97
Hill KP, Rice LS, Connery HS, Weiss RD

The surge in opioid abuse highlights the importance of questioning patients about their… Continue reading

Drug and Alcohol Rehabilitation: Twenty-Four-Hour Ambulatory Blood Pressure Monitoring in Hypertension: An Evidence-Based Analysis.

Twenty-four-hour ambulatory blood pressure monitoring in hypertension: an evidence-based analysis.

Filed under: Drug and Alcohol Rehabilitation

Ont Health Technol Assess Ser. 2012; 12(15): 1-65

The objective of this health technology assessment was to determine the clinical effectiveness and cost-effectiveness… Continue reading

Drug and Alcohol Rehabilitation: Adva-27a, a Novel Podophyllotoxin Derivative Found to Be Effective Against Multidrug Resistant Human Cancer Cells.

Adva-27a, a Novel Podophyllotoxin Derivative Found to Be Effective against Multidrug Resistant Human Cancer Cells.

Filed under: Drug and Alcohol Rehabilitation

Anticancer Res. 2012 Oct; 32(10): 4423-32
Merzouki A, Buschmann MD, Jean M, Young RS, Liao S, Gal S,… Continue reading

Wilms’ Tumor-1 Transcript in Peripheral Blood Helps Diagnose Acute Myeloid Leukemia and Myelodysplastic Syndrome in Patients With Pancytopenia.

Wilms’ tumor-1 transcript in peripheral blood helps diagnose acute myeloid leukemia and myelodysplastic syndrome in patients with pancytopenia.

Filed under: Drug and Alcohol Rehabilitation

Anticancer Res. 2012 Oct; 32(10): 4479-83
Yamauchi T, Matsuda Y, Takai M, Tasaki T, Hosono… Continue reading

Role of Reactive Oxygen Species in the Synergistic Cytotoxicity of Safingol-Based Combination Regimens With Conventional Chemotherapeutics.

Role of reactive oxygen species in the synergistic cytotoxicity of safingol-based combination regimens with conventional chemotherapeutics.

Filed under: Drug and Alcohol Rehabilitation

Oncol Lett. 2011 Sep 1; 2(5): 905-910
Ling LU, Tan KB, Chiu GN

Exploiting the sensitivity of cancer cells to reactive oxygen species (ROS) has been suggested as a strategy for the selective elimination of cancer cells. In this study, the ROS-generating sphingolipid safingol was combined with various conventional chemotherapeutics, and the potential synergism of the safingol-based combination regimen was assessed using a panel of cancer cell lines. The IC(50) values of safingol using as a single agent were 1.4-6.3 µM, which are concentrations that are clinically achievable. While synergism was dependent on the drug molar ratios, a 4:1 molar ratio of safingol to conventional chemotherapeutics exhibited a moderate to strong synergism in MDA-MB-231, JIMT-1, SKOV-3, U937 and KB cells, with combination indices ranging from 0.07 to 0.77. Furthermore, the addition of safingol may reduce the concentrations of conventional chemotherapeutics required to achieve 90% cell-kill by 1 to >3 log-folds. A significant… Continue reading

A Screening Method for the ALK Fusion Gene in NSCLC.

A Screening Method for the ALK Fusion Gene in NSCLC.

Filed under: Drug and Alcohol Rehabilitation

Front Oncol. 2012; 2: 24
Murakami Y, Mitsudomi T, Yatabe Y

Lung cancer research has recently made significant progress in understanding the molecular… Continue reading