drugs of abuse

Lipids and Addiction: How Sex Steroids, Prostaglandins, and Cannabinoids Interact With Drugs of Abuse.

Lipids and addiction: how sex steroids, prostaglandins, and cannabinoids interact with drugs of abuse.

Ann N Y Acad Sci. 2013 Mar 19;
Leishman E, Kokesh KJ, Bradshaw HB

Lipidomics aims to identify and characterize all endogenous species of lipids… Continue reading

Molecular Mechanisms of Cannabinoid Addiction.

Molecular mechanisms of cannabinoid addiction.

Curr Opin Neurobiol. 2013 Mar 12;
Fratta W, Fattore L

Cannabis is the world’s most widely used illicit substance, with an estimated number of 119-224 million users worldwide. In recent years we assisted to… Continue reading

Patterned Three-Dimensional Encapsulation of Embryonic Stem Cells Using Dielectrophoresis and Stereolithography.

Patterned Three-Dimensional Encapsulation of Embryonic Stem Cells using Dielectrophoresis and Stereolithography.

Adv Healthc Mater. 2013 Mar; 2(3): 450-8
Bajaj P, Marchwiany D, Duarte C, Bashir R

Controlling the assembly of cells in three dimensions is very important for engineering… Continue reading

Neuropeptide Y Y5 Receptor Antagonism Causes Faster Extinction and Attenuates Reinstatement in Cocaine-Induced Place Preference.

Neuropeptide Y Y5 receptor antagonism causes faster extinction and attenuates reinstatement in cocaine-induced place preference.

Pharmacol Biochem Behav. 2013 Feb 26;
Sørensen G, Wörtwein G, Fink-Jensen A, Woldbye DP

Several studies have suggested a role for neuropeptide Y (NPY)… Continue reading

Self-Concept Deficits in Massively Multiplayer Online Role-Playing Games Addiction.

Self-Concept Deficits in Massively Multiplayer Online Role-Playing Games Addiction.

Eur Addict Res. 2013 Feb 15; 19(5): 227-234
Leménager T, Gwodz A, Richter A, Reinhard I, Kämmerer N, Sell M, Mann K

Background: Previous studies on Internet addiction point towards… Continue reading

Transcriptional Mechanisms of Drug Addiction.

Transcriptional mechanisms of drug addiction.

Clin Psychopharmacol Neurosci. 2012 Dec; 10(3): 136-43
Nestler EJ

Regulation of gene expression is considered a plausible mechanism of drug addiction given the stability of behavioral abnormalities that define an addicted state. Numerous transcription… Continue reading

Natural and Drug Rewards Act on Common Neural Plasticity Mechanisms With ?FosB as a Key Mediator.

Natural and Drug Rewards Act on Common Neural Plasticity Mechanisms with ?FosB as a Key Mediator.

J Neurosci. 2013 Feb 20; 33(8): 3434-3442
Pitchers KK, Vialou V, Nestler EJ, Laviolette SR, Lehman MN, Coolen LM

Drugs of abuse induce… Continue reading

Crizotinib Induces PUMA-Dependent Apoptosis in Colon Cancer Cells.

Crizotinib induces PUMA-dependent apoptosis in colon cancer cells.

Filed under: Addiction Rehab

Mol Cancer Ther. 2013 Feb 20;
Zheng X, He K, Zhang L, Yu J

Oncogenic alterations in MET or ALK have been identified in a variety of… Continue reading

Addiction and Corticotropin-Releasing Hormone Type 1 Receptor Antagonist Medications.

Addiction and corticotropin-releasing hormone type 1 receptor antagonist medications.

Filed under: Addiction Rehab

Ann N Y Acad Sci. 2013 Feb 11;
Contoreggi C, Lee MR, Chrousos G

Derangements in corticotropin-releasing hormone (CRH) through its type 1 receptor (CRHR1) have… Continue reading

Addiction Rehab: Modulating Cocaine Vaccine Potency Through Hapten Fluorination.

Modulating Cocaine Vaccine Potency Through Hapten Fluorination.

Filed under: Addiction Rehab

J Am Chem Soc. 2013 Feb 11;
Cai X, Tsuchikama K, Janda KD

Cocaine addiction is a long-lasting relapsing illness characterized by cycles of abuse, abstinence and reinstatement,… Continue reading