drug resistance

Gene and microRNA Expression Reveals Sensitivity to Paclitaxel in Laryngeal Cancer Cell Line.

Gene and microRNA expression reveals sensitivity to paclitaxel in laryngeal cancer cell line.

Int J Clin Exp Pathol. 2013; 6(7): 1351-61
Xu CZ, Xie J, Jin B, Chen XW, Sun ZF, Wang BX, Dong P

Paclitaxel is a widely… Continue reading

MicroRNA-200c Regulates the Sensitivity of Chemotherapy of Gastric Cancer SGC7901/DDP Cells by Directly Targeting RhoE.

MicroRNA-200c Regulates the Sensitivity of Chemotherapy of Gastric Cancer SGC7901/DDP Cells by Directly Targeting RhoE.

Pathol Oncol Res. 2013 Jul 3;
Chang L, Guo F, Wang Y, Lv Y, Huo B, Wang L, Liu W

Gastric cancer remains a… Continue reading

Exploring the Ligand-Protein Networks in Traditional Chinese Medicine: Current Databases, Methods, and Applications.

Exploring the ligand-protein networks in traditional chinese medicine: current databases, methods, and applications.

Evid Based Complement Alternat Med. 2013; 2013: 806072
Zhao M, Zhou Q, Ma W, Wei DQ

The traditional Chinese medicine (TCM), which has thousands of years… Continue reading

Angiogenesis Inhibitor Bevacizumab Increases the Risk of Ischemic Heart Disease Associated With Chemotherapy: A Meta-Analysis.

Angiogenesis Inhibitor Bevacizumab Increases the Risk of Ischemic Heart Disease Associated with Chemotherapy: A Meta-Analysis.

PLoS One. 2013; 8(6): e66721
Chen XL, Lei YH, Liu CF, Yang QF, Zuo PY, Liu CY, Chen CZ, Liu YW

Concerns have arisen… Continue reading

Exceptions to and Deviations From the INN Common Stem System.

Exceptions to and deviations from the INN common stem system.

Prescrire Int. 2013 May; 22(138): 138-9

For various reasons, mainly related to the history of the drug and of drug nomenclature, some INNs lack a common stem. As INN… Continue reading

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation.

DISSECT Method Using PNA-LNA Clamp Improves Detection of EGFR T790m Mutation.

PLoS One. 2013; 8(6): e67782
Guha M, Castellanos-Rizaldos E, Makrigiorgos GM

Non-small cell lung cancer (NSCLC) patients treated with small molecule EGFR inhibitors, such as gefitinib, frequently develop… Continue reading

Investigation of the Mechanisms Governing Doxorubicin and Irinotecan Release From Drug-Eluting Beads: Mathematical Modeling and Experimental Verification.

Investigation of the mechanisms governing doxorubicin and irinotecan release from drug-eluting beads: mathematical modeling and experimental verification.

J Mater Sci Mater Med. 2013 Jun 25;
Biondi M, Fusco S, Lewis AL, Netti PA

Drug-eluting beads (DEBs) are embolising devices… Continue reading

[Vemurafenib (Zelboraf) in the Therapy of Melanoma].

[Vemurafenib (Zelboraf) in the therapy of melanoma].

Magy Onkol. 2013 Jun; 57(2): 110-3
Liszkay G

The incidence of malignant melanoma is continuously rising, but the therapy of advanced melanoma remains insufficient. Advances in the understanding of the immunological and… Continue reading

Crizotinib in the Treatment of Non-Small-Cell Lung Carcinoma.

Crizotinib in the treatment of non-small-cell lung carcinoma.

Contemp Oncol (Pozn). 2012; 16(6): 480-484
P?u?a?ski A, Piórek A, Krzakowski M

Recent studies have demonstrated the benefit of EGFR tyrosine kinase inhibitors in the treatment of advanced non-small-cell lung cancer… Continue reading

Antimicrobial Activity and Probable Mechanisms of Action of Medicinal Plants of Kenya: Withania Somnifera, Warbugia Ugandensis, Prunus Africana and Plectrunthus Barbatus.

Antimicrobial Activity and Probable Mechanisms of Action of Medicinal Plants of Kenya: Withania somnifera, Warbugia ugandensis, Prunus africana and Plectrunthus barbatus.

PLoS One. 2013; 8(6): e65619
Mwitari PG, Ayeka PA, Ondicho J, Matu EN, Bii CC

Withania somnifera, Warbugia… Continue reading