Generation and Validation of a Zebrafish Model of EAST (Epilepsy, Ataxia, Sensorineural Deafness and Tubulopathy) Syndrome.
Generation and validation of a zebrafish model of EAST (Epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome.
Dis Model Mech. 2013 Feb 14;
Mahmood F, Mozere M, Zdebik AA, Stanescu HC, Tobin J, Beales PL, Kleta R, Bockenhauer D, Russell… Continue reading
A Method to Measure Hydrolytic Activity of Adenosinetriphosphatases (ATPases).
A method to measure hydrolytic activity of adenosinetriphosphatases (ATPases).
PLoS One. 2013; 8(3): e58615
Bartolommei G, Moncelli MR, Tadini-Buoninsegni F
The detection of small amounts (nanomoles) of inorganic phosphate has a great interest in biochemistry. In particular, phosphate detection… Continue reading
The C-Terminal Region Mesd Peptide Mimics Full-Length Mesd and Acts as an Inhibitor of Wnt/?-Catenin Signaling in Cancer Cells.
The C-Terminal Region Mesd Peptide Mimics Full-Length Mesd and Acts as an Inhibitor of Wnt/?-Catenin Signaling in Cancer Cells.
PLoS One. 2013; 8(2): e58102
Lin C, Lu W, Zhang W, Londoño-Joshi AI, Buchsbaum DJ, Bu G, Li Y
While… Continue reading
Pterostilbene Acts Through Metastasis-Associated Protein 1 to Inhibit Tumor Growth, Progression and Metastasis in Prostate Cancer.
Pterostilbene Acts through Metastasis-Associated Protein 1 to Inhibit Tumor Growth, Progression and Metastasis in Prostate Cancer.
PLoS One. 2013; 8(3): e57542
Li K, Dias SJ, Rimando AM, Dhar S, Mizuno CS, Penman AD, Lewin JR, Levenson AS
The development… Continue reading
Drug Rehab Centers in Llinois | Free Drug Rehab Centers in Illinois
Drug Rehab Centers in llinois | Free Drug Rehab Centers in Illinois – illinoisrehabcenters.org Drug Rehab Centers in llinois focuses on helping addicts get clean through counseling, clean and sober housing, and Illinois detox services. Call 877-281-6142 http
Future Prospects for Pharmacogenetics in the Quest for Personalized Medicine.
Future prospects for pharmacogenetics in the quest for personalized medicine.
J Psychosoc Nurs Ment Health Serv. 2012 Dec; 50(12): 13-6
Howland RH
Understanding pharmacogenetic differences in drug response and tolerability has been an important area of research in personalized… Continue reading
The Μ Opioid Receptor and Ligands Acting at the Μ Opioid Receptor, as Therapeutics and Potential Therapeutics.
The µ Opioid Receptor and Ligands Acting at the µ Opioid Receptor, as Therapeutics and Potential Therapeutics.
Curr Pharm Des. 2013 Feb 20;
Spetea M, Asim MF, Wolber G, Schmidhammer H
Although the µ opioid receptor (MOR) was pharmacologically… Continue reading
Kinetic Modeling-Based Detection of Genetic Signatures That Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network.
Kinetic Modeling-Based Detection of Genetic Signatures that Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network.
Cancer Res. 2013 Feb 27;
Vera J, Schmitz U, Lai X, Engelmann D, Khan FM, Wolkenhauer O, Putzer BM
Drug resistance is a major cause of… Continue reading
Cover Image, Volume 34, Issue 9.
Cover image, volume 34, issue 9.
J Comput Chem. 2013 Apr 5; 34(9): i-ii
The rapid development of drug resistance in microbes, the toxicity, and side effects of existing anti-infectious drugs are factors stimulating the effort directed toward a… Continue reading
Gene Expression and Thiopurine Metabolite Profiling in Inflammatory Bowel Disease – Novel Clues to Drug Targets and Disease Mechanisms?
Gene expression and thiopurine metabolite profiling in inflammatory bowel disease – novel clues to drug targets and disease mechanisms?
PLoS One. 2013; 8(2): e56989
Haglund S, Almer S, Peterson C, Söderman J
Thiopurines are effective to induce and maintain remission in inflammatory bowel disease (IBD). The methyl thioinosine monophosphate (meTIMP)/6-thioguanine nucleotide (6-TGN) concentration ratio has been associated with drug efficacy. Here we explored the molecular basis of differences in metabolite profiles and in relation to disease activity.Transcriptional profiles in blood samples from an exploratory IBD-patient cohort (n?=?21) with a normal thiopurine S-methyltransferase phenotype and meTIMP/6-TGN ratios >20, 10.0-14.0 and ?4, respectively, were assessed… Continue reading