clinical trials

Assay Sensitivity and Study Features in Neuropathic Pain Trials: An ACTTION Meta-Analysis.

Assay sensitivity and study features in neuropathic pain trials: An ACTTION meta-analysis.

Neurology. 2013 May 22;
Dworkin RH, Turk DC, Peirce-Sandner S, He H, McDermott MP, Farrar JT, Katz NP, Lin AH, Rappaport BA, Rowbotham MC

OBJECTIVE: Our objective… Continue reading

Propofol for Procedural Sedation in the Emergency Department: A Qualitative Systematic Review (June).

Propofol for Procedural Sedation in the Emergency Department: A Qualitative Systematic Review (June).

Ann Pharmacother. 2013 May 21;
Black E, Campbell SG, Magee K, Zed PJ

OBJECTIVE:To evaluate the efficacy and safety of propofol compared to other agents for… Continue reading

Publication Bias, With a Focus on Psychiatry: Causes and Solutions.

Publication Bias, with a Focus on Psychiatry: Causes and Solutions.

CNS Drugs. 2013 May 22;
Turner EH

Publication bias undermines the integrity of the evidence base by inflating apparent drug efficacy and minimizing drug harms, thus skewing the risk-benefit… Continue reading

Corticomuscular Coherence Analysis on Hand Movement Distinction for Active Rehabilitation.

Corticomuscular Coherence Analysis on Hand Movement Distinction for Active Rehabilitation.

Comput Math Methods Med. 2013; 2013: 908591
Lou X, Xiao S, Qi Y, Hu X, Wang Y, Zheng X

Active rehabilitation involves patient’s voluntary thoughts as the control signals… Continue reading

A Clinical Treatment Intervention for Dysphoria: Externalizing Metaphors Therapy.

A Clinical Treatment Intervention for Dysphoria: Externalizing Metaphors Therapy.

Clin Psychol Psychother. 2013 May 20;
McGuinty E, Armstrong D, Carrière AM

The purpose of this article is to explore a novel, short-term treatment intervention for internalizing behaviours. This intervention… Continue reading

Exploiting Tumor Vulnerabilities: Epigenetics, Cancer Metabolism and the mTOR Pathway in the Era of Personalized Medicine.

Exploiting tumor vulnerabilities: epigenetics, cancer metabolism and the mTOR pathway in the era of Personalized Medicine.

Cancer Res. 2013 May 17;
Muñoz-Pinedo C, González-Suárez E, Portela A, Gentilella A, Esteller M

Patient stratification according to drug responses, together with… Continue reading

Supplementation With Vitamin D Does Not Increase Serum Testosterone Levels in Healthy Males.

Supplementation with Vitamin D Does not Increase Serum Testosterone Levels in Healthy Males.

Horm Metab Res. 2013 May 17;
Jorde R, Grimnes G, Hutchinson MS, Kjærgaard M, Kamycheva E, Svartberg J

Cross-sectional studies indicate a positive relation between serum… Continue reading

Naltrexone With or Without Guanfacine for Preventing Relapse to Opiate Addiction in St.-Petersburg, Russia.

Naltrexone with or without guanfacine for preventing relapse to opiate addiction in St.-Petersburg, Russia.

Drug Alcohol Depend. 2013 May 15;
Krupitsky E, Zvartau E, Blokhina E, Verbitskaya E, Tsoy M, Wahlgren V, Burakov A, Masalov D, Romanova TN, Palatkin… Continue reading

Non-Destructively Shattered Mesoporous Silica for Protein Drug Delivery.

Non-destructively shattered mesoporous silica for protein drug delivery.

Microporous Mesoporous Mater. 2013 Jul 15; 175: 157-160
Lei C, Chen B, Li X, Qi W, Liu J

Mesoporous silicas have been extensively used for entrapping small chemical molecules and biomacromolecules… Continue reading

Drug-Like Property Profiling of Novel Neuroprotective Compounds to Treat Acute Ischemic Stroke: Guidelines to Develop Pleiotropic Molecules.

Drug-Like Property Profiling of Novel Neuroprotective Compounds to Treat Acute Ischemic Stroke: Guidelines to Develop Pleiotropic Molecules.

Transl Stroke Res. 2013 Jun 1; 4(3): 328-342
Lapchak PA

The development of novel neuroprotective compounds to treat acute ischemic stroke (AIS)… Continue reading