Clinical trial

A Practical Guide to the Therapy of Narcolepsy and Hypersomnia Syndromes.

A Practical Guide to the Therapy of Narcolepsy and Hypersomnia Syndromes.

Filed under: Addiction Rehab

Neurotherapeutics. 2012 Oct 11;
Mignot EJ

Narcolepsy and other syndromes associated with excessive daytime sleepiness can be challenging to treat. New classifications now distinguish… Continue reading

Addiction Rehab: Combined Action of MK-801 and Ceftriaxone Impairs the Acquisition and Reinstatement of Morphine-Induced Conditioned Place Preference, and Delays Morphine Extinction in Rats.

Combined action of MK-801 and ceftriaxone impairs the acquisition and reinstatement of morphine-induced conditioned place preference, and delays morphine extinction in rats.

Filed under: Addiction Rehab

Neurosci Bull. 2012 Oct; 28(5): 567-76
Fan Y, Niu H, Rizak JD, Li… Continue reading

Reprofiling a Classical Anthelmintic, Pyrvinium Pamoate, as an Anti-Cancer Drug Targeting Mitochondrial Respiration.

Reprofiling a classical anthelmintic, pyrvinium pamoate, as an anti-cancer drug targeting mitochondrial respiration.

Filed under: Drug and Alcohol Rehabilitation

Front Oncol. 2012; 2: 137
Ishii I, Harada Y, Kasahara T

Pyrvinium pamoate (PP) is an FDA-approved classical anthelmintic, but… Continue reading

A Transformative Subfield in Rehabilitation Science at the Nexus of New Technologies, Aging, and Disability.

A transformative subfield in rehabilitation science at the nexus of new technologies, aging, and disability.

Filed under: Rehab Centers

Front Psychol. 2012; 3: 340
Winstein CJ, Requejo PS, Zelinski EM, Mulroy SJ, Crimmins EM

We argue that a silo… Continue reading

Nucleus Accumbens Surgery for Addiction.

Nucleus Accumbens Surgery for Addiction.

Filed under: Addiction Rehab

World Neurosurg. 2012 Oct 6;
Li N, Wang J, Wang XL, Chang CW, Ge SN, Gao L, Wu HM, Zhao HK, Geng N, Gao GD

Opiate addiction remains intractable in… Continue reading

The Association Between Psychosocial Care by Physicians and Patients’ Trust: A Retrospective Analysis of Severely Injured Patients in Surgical Intensive Care Units.

The association between psychosocial care by physicians and patients’ trust: a retrospective analysis of severely injured patients in surgical intensive care units.

Filed under: Rehab Centers

Psychosoc Med. 2012; 9: Doc04
Thüm S, Janssen C, Pfaff H, Lefering R,… Continue reading

Spiritual Well-Being May Buffer Psychological Distress in Patients With Implantable Cardioverter Defibrillators (ICD).

Spiritual well-being may buffer psychological distress in patients with implantable cardioverter defibrillators (ICD).

Filed under: Depression Treatment

J Evid Based Complementary Altern Med. 2012 Oct 1; 17(3): 148-154
Salmoirago-Blotcher E, Crawford S, Tran C, Goldberg R, Rosenthal L, Ockene… Continue reading

Drug and Alcohol Rehabilitation: Gestational Naltrexone Ameliorates Fetal Ethanol Exposures Enhancing Effect on the Postnatal Behavioral and Neural Response to Ethanol.

Gestational naltrexone ameliorates fetal ethanol exposures enhancing effect on the postnatal behavioral and neural response to ethanol.

Filed under: Drug and Alcohol Rehabilitation

Exp Biol Med (Maywood). 2012 Oct 8;
Youngentob SL, Kent PF, Youngentob LM

The association between… Continue reading

Drug and Alcohol Rehabilitation: Sustainable Tuberculosis Drug Development.

Sustainable tuberculosis drug development.

Filed under: Drug and Alcohol Rehabilitation

Clin Infect Dis. 2012 Oct 5;
Wallis RS

Six new anti-tuberculosis compounds in 4 classes are presently in clinical trials. Although these show substantial promise for drug-resistant (DR) tuberculosis,… Continue reading

Eating Disorders: Development and Validation of the Self-Management Profile for Type 2 Diabetes (SMP-T2D).

Development and validation of the self-management profile for type 2 diabetes (SMP-T2D).

Filed under: Eating Disorders

Health Qual Life Outcomes. 2012 Oct 5; 10(1): 125
Peyrot M, Bushnell DM, Best JH, Martin ML, Cameron A, Patrick DL

ABSTRACT: BACKGROUND: This study evaluated the measurement properties of a newly developed instrument — the Self-Management Profile for Type 2 Diabetes (SMP-T2D). METHODS: The 18-item SMP-T2D assesses 12 constructs: level and perceived ease of performance in five self-care domains (blood glucose monitoring, medication-taking, healthy eating, being physically active, and coping), and two global constructs (ease of weight management, confidence with ability to manage diabetes). Validation analyses were based on two studies involved 240 patients with T2D, Study 1 (Clinicaltrials.gov #NCT00637273) with SMP-T2D administration supplemented by SMP-T2D retest one week later, and Study 2 (Clinical trials.gov #NCT00877890) with SMP-T2D administration supplemented by 24-week SMP-T2D follow-up after medication change. Validation included clinical indicators and measures of patient reported quality of life, psychological well-being and treatment outcomes. RESULTS: All multi-item SMP-T2D measures showed acceptable internal consistency (alphas = 0.71 to 0.87); ten measures had test-retest reliability >0.75. Correlations… Continue reading