cell lines

Efficient Generation of Stable Bispecific IgG1 by Controlled Fab-Arm Exchange.

Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange.

Proc Natl Acad Sci U S A. 2013 Mar 11;
Labrijn AF, Meesters JI, de Goeij BE, van den Bremer ET, Neijssen J, van Kampen MD, Strumane K, Verploegen… Continue reading

Generation and Validation of a Zebrafish Model of EAST (Epilepsy, Ataxia, Sensorineural Deafness and Tubulopathy) Syndrome.

Generation and validation of a zebrafish model of EAST (Epilepsy, ataxia, sensorineural deafness and tubulopathy) syndrome.

Dis Model Mech. 2013 Feb 14;
Mahmood F, Mozere M, Zdebik AA, Stanescu HC, Tobin J, Beales PL, Kleta R, Bockenhauer D, Russell… Continue reading

The C-Terminal Region Mesd Peptide Mimics Full-Length Mesd and Acts as an Inhibitor of Wnt/?-Catenin Signaling in Cancer Cells.

The C-Terminal Region Mesd Peptide Mimics Full-Length Mesd and Acts as an Inhibitor of Wnt/?-Catenin Signaling in Cancer Cells.

PLoS One. 2013; 8(2): e58102
Lin C, Lu W, Zhang W, Londoño-Joshi AI, Buchsbaum DJ, Bu G, Li Y

While… Continue reading

Diminished Vision in Healthy Aging Is Associated With Increased Retinal L-Type Voltage Gated Calcium Channel Ion Influx.

Diminished vision in healthy aging is associated with increased retinal L-type voltage gated calcium channel ion influx.

PLoS One. 2013; 8(2): e56340
Bissig D, Goebel D, Berkowitz BA

Extensive evidence implicates an increase in hippocampal L-type voltage-gated calcium channel… Continue reading

The Μ Opioid Receptor and Ligands Acting at the Μ Opioid Receptor, as Therapeutics and Potential Therapeutics.

The µ Opioid Receptor and Ligands Acting at the µ Opioid Receptor, as Therapeutics and Potential Therapeutics.

Curr Pharm Des. 2013 Feb 20;
Spetea M, Asim MF, Wolber G, Schmidhammer H

Although the µ opioid receptor (MOR) was pharmacologically… Continue reading

Kinetic Modeling-Based Detection of Genetic Signatures That Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network.

Kinetic Modeling-Based Detection of Genetic Signatures that Provide Chemoresistance via the E2F1-p73/DNp73-miR-205 Network.

Cancer Res. 2013 Feb 27;
Vera J, Schmitz U, Lai X, Engelmann D, Khan FM, Wolkenhauer O, Putzer BM

Drug resistance is a major cause of… Continue reading

A More Balanced Approach to Drug-Grapefruit Juice Interactions.

A more balanced approach to drug-grapefruit juice interactions.

BMJ. 2013; 346: f1073
Backman WD, Bakhai A

HubMed – drug

 

Increased Glucagon-like peptide-1 secretion may be involved in anti-diabetic effects of ginsenosides.

J Endocrinol. 2013 Feb 26;
Liu… Continue reading

Effects of the Pimelic Diphenylamide Histone Deacetylase Inhibitor HDACi 4b on the R6/2 and N171-82Q Mouse Models of Huntington’s Disease.

Effects of the Pimelic Diphenylamide Histone Deacetylase Inhibitor HDACi 4b on the R6/2 and N171-82Q Mouse Models of Huntington’s Disease.

PLoS Curr. 2013; 5:
Chen JY, Wang E, Galvan L, Huynh M, Joshi P, Cepeda C, Levine MS

This… Continue reading

Psychiatric Consequences of Needlestick Injury.

Psychiatric consequences of needlestick injury.

Occup Med (Lond). 2013 Feb 21;
Green B, Griffiths EC

BackgroundNeedlestick injuries (NSIs) are a common occupational hazard with potential physical health effects, including viral infections such as hepatitis and HIV. Less appreciated are… Continue reading

Drug and Alcohol Rehabilitation: Identification of Unique Synergistic Drug Combinations Associated With Downexpression of Survivin in a Preclinical Breast Cancer Model System.

Identification of unique synergistic drug combinations associated with downexpression of survivin in a preclinical breast cancer model system.

Filed under: Drug and Alcohol Rehabilitation

Anticancer Drugs. 2012 Mar; 23(3): 272-9
Budman DR, Calabro A, Rosen L, Lesser M

HubMed… Continue reading