cell lines

Comparison of Responses of Human Melanoma Cell Lines to MEK and BRAF Inhibitors.

Comparison of responses of human melanoma cell lines to MEK and BRAF inhibitors.

Front Genet. 2013; 4: 66
Stones CJ, Kim JE, Joseph WR, Leung E, Marshall ES, Finlay GJ, Shelling AN, Baguley BC

The NRAS and BRAF genes… Continue reading

Secondary Bacterial Infections of Buruli Ulcer Lesions Before and After Chemotherapy With Streptomycin and Rifampicin.

Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin.

PLoS Negl Trop Dis. 2013 May; 7(5): e2191
Yeboah-Manu D, Kpeli GS, Ruf MT, Asan-Ampah K, Quenin-Fosu K, Owusu-Mireku E, Paintsil A, Lamptey I,… Continue reading

Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(Ethylsulfinyl)-6-(Trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.

Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.

Drug Metab Dispos. 2013 May 7;
Eng H, Sharma R, McDonald TS, Edmonds DJ, Fortin JP, Li X, Stevens… Continue reading

Viability Reagent, PrestoBlue, in Comparison With Other Available Reagents, Utilized in Cytotoxicity and Antimicrobial Assays.

Viability Reagent, PrestoBlue, in Comparison with Other Available Reagents, Utilized in Cytotoxicity and Antimicrobial Assays.

Int J Microbiol. 2013; 2013: 420601
Lall N, Henley-Smith CJ, De Canha MN, Oosthuizen CB, Berrington D

This study compared different commercially available viability… Continue reading

Machine Learning Prediction of Cancer Cell Sensitivity to Drugs Based on Genomic and Chemical Properties.

Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties.

PLoS One. 2013; 8(4): e61318
Menden MP, Iorio F, Garnett M, McDermott U, Benes CH, Ballester PJ, Saez-Rodriguez J

Predicting the response of a… Continue reading

A New Class of Small Molecule Inhibitor of BMP Signaling.

A New Class of Small Molecule Inhibitor of BMP Signaling.

PLoS One. 2013; 8(4): e62721
Sanvitale CE, Kerr G, Chaikuad A, Ramel MC, Mohedas AH, Reichert S, Wang Y, Triffitt JT, Cuny GD, Yu PB, Hill CS, Bullock AN… Continue reading

Effects of 5-Fluorouracil in Nuclear and Cellular Morphology, Proliferation, Cell Cycle, Apoptosis, Cytoskeletal and Caveolar Distribution in Primary Cultures of Smooth Muscle Cells.

Effects of 5-Fluorouracil in nuclear and cellular morphology, proliferation, cell cycle, apoptosis, cytoskeletal and caveolar distribution in primary cultures of smooth muscle cells.

PLoS One. 2013; 8(4): e63177
Filgueiras Mde C, Morrot A, Soares PM, Costa ML, Mermelstein C… Continue reading

Dissecting the PI3K Signaling Axis in Pediatric Solid Tumors: Novel Targets for Clinical Integration.

Dissecting the PI3K Signaling Axis in Pediatric Solid Tumors: Novel Targets for Clinical Integration.

Front Oncol. 2013; 3: 93
Loh AH, Brennan RC, Lang WH, Hickey RJ, Malkas LH, Sandoval JA

Children with solid tumors represent a unique population.… Continue reading

Correlation of Angiogenic Biomarker Signatures With Clinical Outcomes in Metastatic Colorectal Cancer Patients Receiving Capecitabine, Oxaliplatin, and Bevacizumab.

Correlation of angiogenic biomarker signatures with clinical outcomes in metastatic colorectal cancer patients receiving capecitabine, oxaliplatin, and bevacizumab.

Cancer Med. 2013 Apr; 2(2): 234-42
Liu Y, Starr MD, Bulusu A, Pang H, Wong NS, Honeycutt W, Amara A, Hurwitz… Continue reading

Human Experimental Pain Models: A Review of Standardized Methods in Drug Development.

Human experimental pain models: A review of standardized methods in drug development.

J Res Med Sci. 2012 Jun; 17(6): 587-95
Reddy KS, Naidu MU, Rani PU, Rao TR

Human experimental pain models are essential in understanding the pain mechanisms… Continue reading