cancer cells

Crosstalk From Non-Cancerous Mitochondria Can Inhibit Tumor Properties of Metastatic Cells by Suppressing Oncogenic Pathways.

Crosstalk from non-cancerous mitochondria can inhibit tumor properties of metastatic cells by suppressing oncogenic pathways.

PLoS One. 2013; 8(5): e61747
Kaipparettu BA, Ma Y, Park JH, Lee TL, Zhang Y, Yotnda P, Creighton CJ, Chan WY, Wong LJ

Mitochondrial-nucleus… Continue reading

Secondary Bacterial Infections of Buruli Ulcer Lesions Before and After Chemotherapy With Streptomycin and Rifampicin.

Secondary bacterial infections of buruli ulcer lesions before and after chemotherapy with streptomycin and rifampicin.

PLoS Negl Trop Dis. 2013 May; 7(5): e2191
Yeboah-Manu D, Kpeli GS, Ruf MT, Asan-Ampah K, Quenin-Fosu K, Owusu-Mireku E, Paintsil A, Lamptey I,… Continue reading

Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(Ethylsulfinyl)-6-(Trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.

Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.

Drug Metab Dispos. 2013 May 7;
Eng H, Sharma R, McDonald TS, Edmonds DJ, Fortin JP, Li X, Stevens… Continue reading

In Vitro Selection of Mutant HDM2 Resistant to Nutlin Inhibition.

In Vitro Selection of Mutant HDM2 Resistant to Nutlin Inhibition.

PLoS One. 2013; 8(4): e62564
Wei SJ, Joseph T, Sim AY, Yurlova L, Zolghadr K, Lane D, Verma C, Ghadessy F

HDM2 binds to the p53 tumour suppressor and… Continue reading

Prediction and Validation of Gene-Disease Associations Using Methods Inspired by Social Network Analyses.

Prediction and validation of gene-disease associations using methods inspired by social network analyses.

PLoS One. 2013; 8(5): e58977
Singh-Blom UM, Natarajan N, Tewari A, Woods JO, Dhillon IS, Marcotte EM

Correctly identifying associations of genes with diseases has long… Continue reading

Effects of 5-Fluorouracil in Nuclear and Cellular Morphology, Proliferation, Cell Cycle, Apoptosis, Cytoskeletal and Caveolar Distribution in Primary Cultures of Smooth Muscle Cells.

Effects of 5-Fluorouracil in nuclear and cellular morphology, proliferation, cell cycle, apoptosis, cytoskeletal and caveolar distribution in primary cultures of smooth muscle cells.

PLoS One. 2013; 8(4): e63177
Filgueiras Mde C, Morrot A, Soares PM, Costa ML, Mermelstein C… Continue reading

Suboxone Pharma Foibles/FDA Does Its Job Well.

Suboxone Pharma Foibles/FDA Does Its Job Well.

R I Med J (2013). 2013; 96(4): 13
Gordon A, Kretzschmar A, Gilbert E

HubMed – addiction

 

Pyrvinium targets autophagy addiction to promote cancer cell death.

Cell Death Dis. 2013;… Continue reading

Correlation of Angiogenic Biomarker Signatures With Clinical Outcomes in Metastatic Colorectal Cancer Patients Receiving Capecitabine, Oxaliplatin, and Bevacizumab.

Correlation of angiogenic biomarker signatures with clinical outcomes in metastatic colorectal cancer patients receiving capecitabine, oxaliplatin, and bevacizumab.

Cancer Med. 2013 Apr; 2(2): 234-42
Liu Y, Starr MD, Bulusu A, Pang H, Wong NS, Honeycutt W, Amara A, Hurwitz… Continue reading

An Indirect Resilience to Addiction.

An indirect resilience to addiction.

Nat Neurosci. 2013 May; 16(5): 521-3
Picciotto MR

HubMed – addiction

 

1, 25 Dihydroxyvitamin D Regulation of Glucose Metabolism in Harvey-ras Transformed MCF10A Human Breast Epithelial Cells.

J Steroid Biochem Mol Biol.… Continue reading

Evaluation of Digoxin Concentration After Loading Dose in Patients With Renal Dysfunction.

Evaluation of digoxin concentration after loading dose in patients with renal dysfunction.

Can J Hosp Pharm. 2013 Mar; 66(2): 104-9
Pawlosky N, Macdonald E, Patel R, Kanji S

Loading dose recommendations for digoxin are based on the volume of… Continue reading