Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(Ethylsulfinyl)-6-(Trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.
Demonstration of the Innate Electrophilicity of 4-(3-(Benzyloxy)phenyl)-2-(ethylsulfinyl)-6-(trifluoromethyl)pyrimidine (BETP), a Small Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 (GLP-1) Receptor.
Drug Metab Dispos. 2013 May 7;
Eng H, Sharma R, McDonald TS, Edmonds DJ, Fortin JP, Li X, Stevens… Continue reading
In Vitro Selection of Mutant HDM2 Resistant to Nutlin Inhibition.
In Vitro Selection of Mutant HDM2 Resistant to Nutlin Inhibition.
PLoS One. 2013; 8(4): e62564
Wei SJ, Joseph T, Sim AY, Yurlova L, Zolghadr K, Lane D, Verma C, Ghadessy F
HDM2 binds to the p53 tumour suppressor and… Continue reading
A New Class of Small Molecule Inhibitor of BMP Signaling.
A New Class of Small Molecule Inhibitor of BMP Signaling.
PLoS One. 2013; 8(4): e62721
Sanvitale CE, Kerr G, Chaikuad A, Ramel MC, Mohedas AH, Reichert S, Wang Y, Triffitt JT, Cuny GD, Yu PB, Hill CS, Bullock AN… Continue reading
Effects of 5-Fluorouracil in Nuclear and Cellular Morphology, Proliferation, Cell Cycle, Apoptosis, Cytoskeletal and Caveolar Distribution in Primary Cultures of Smooth Muscle Cells.
Effects of 5-Fluorouracil in nuclear and cellular morphology, proliferation, cell cycle, apoptosis, cytoskeletal and caveolar distribution in primary cultures of smooth muscle cells.
PLoS One. 2013; 8(4): e63177
Filgueiras Mde C, Morrot A, Soares PM, Costa ML, Mermelstein C… Continue reading
An Indirect Resilience to Addiction.
An indirect resilience to addiction.
Nat Neurosci. 2013 May; 16(5): 521-3
Picciotto MR
1, 25 Dihydroxyvitamin D Regulation of Glucose Metabolism in Harvey-ras Transformed MCF10A Human Breast Epithelial Cells.