Current and Emerging Treatments for Absence Seizures in Young Patients.
... exhibit a specific electroclinical semiology, pathophysiology, and pharmacological response profile. A large-scale comparative study has recently confirmed the key role of ethosuximide in the treatment of childhood absence epilepsy, more than 50 years after its introduction. No new antiepileptic… Continue reading
Therapeutic Action of Fluoxetine Is Associated With a Reduction in Prefrontal Cortical miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder.
... miR-1971 Expression Levels in a Mouse Model of Posttraumatic Stress Disorder. Front Psychiatry. 2013; 4: 66Schmidt U, Herrmann L, Hagl K, Novak B, Huber C, Holsboer F, Wotjak CT, Buell DR MicroRNAs (miRNA) are a class of small non-coding… Continue reading
Direct-Acting Antivirals for the Treatment of Chronic Hepatitis C: Open Issues and Future Perspectives.
... in patients who were treated with BMS or SES. Restenosis rate was 0.0% in the DES group and 20.8% in the other group (p = 0.562); it did not differ between BMS and SES (2/11 18.2%, 3/13 23.1%, p… Continue reading
Effects of Propofol, a Sedative-Hypnotic Drug, on the Lipid Profile, Antioxidant Indices, and Cardiovascular Marker Enzymes in Wistar Rats.
... to attenuate oxidative stress and reduce the risk for related neurodegenerative diseases such as Alzheimer’s disease (AD), stroke, multiple sclerosis (MS), Parkinson’s disease (PD), and Huntington’s disease (HD). Polyphenols exhibit strong potential to address the etiology of neurological disorders… Continue reading
Cannabis Use, Addiction Risk and Functional Impairment in Youth Seeking Treatment for Primary Mood or Anxiety Concerns.
... addiction History of depression and previous suicide attempt predict increased risk of suicide attempt following diagnosis of first-episode psychosis. Evid Based Ment Health. 2013 Aug; 16(3): 67Melle I HubMed – addiction Escalation of drug self-administration as a… Continue reading
Role of Kappa-Opioid Receptors in Stress and Anxiety-Related Behavior.
... have stimulated interest in the development of KOR-targeted ligands as therapeutic agents. As one example, it has been suggested that KOR antagonists might have a wide range of indications, including the treatment of depressive, anxiety, and addictive disorders, as… Continue reading