Sleep Bruxism Increases the Risk for Painful Temporomandibular Disorder, Depression and Non-Specific Physical Symptoms.

Sleep bruxism increases the risk for painful temporomandibular disorder, depression and non-specific physical symptoms.

Filed under: Depression Treatment

Br Dent J. 2012 Nov 23; 213(10): 511

Associations between sleep bruxism, TMD and depression.
HubMed – depression


Gaze-Controlled, Computer-Assisted Communication In Intensive Care Unit: “Speaking Through The Eyes”

Filed under: Depression Treatment

Minerva Anestesiol. 2012 Nov 22;
Maringelli F, Brienza N, Scorrano F, Grasso F, Gregoretti C

AIM:The aim of this study was to test the hypothesis that a gaze-controlled communication system (Eye Tracker – ET) can improve communication processes between completely dysarthric ICU patients and the hospital staff, in three main domains: a) basic communication processes (i.e., fundamental needs, desire, and wishes), b) the ability of the medical staff to understand the clinical condition of the patient, and c) the level of frustration experienced by patient, nurses and physicians. METHODS:Fifteen fully conscious medical and surgical patients, 8 physicians, and 15 nurses were included in the study. The experimental procedure was composed by 3 phases: in phase 1 all groups completed the pre-intervention questionnaire; in phase 2 the ET was introduced and tested as a communication device; in phase 3 all groups completed the post-intervention questionnaire. RESULTS: Patients pre-intervention questionnaires showed remarkable communication deficits, without any group effect. Answers of physicians and nurses were pretty much similar to the one of patients. Post-intervention questionnaires showed in all groups a remarkable and statistically significant improvement in different communication domains, as well as a remarkable decrease of anxiety and disphoric thought. Improvement was also reported by physicians and nurses in their ability to understand patient’s clinical conditions. CONCLUSIONS:Our results show an improvement in the quality of the examined parameters. Better communication processes seem also to lead to improvements in several psychological parameters, namely anxiety and drop-out depression perceived by both patients and medical staff. Further controlled studies are needed to define the ET role in ICU.
HubMed – depression


Decrease in the red cell cofactor 2,3-diphosphoglycerate increases hemoglobin oxygen affinity in the hibernating brown bear Ursus arctos.

Filed under: Depression Treatment

Am J Physiol Regul Integr Comp Physiol. 2012 Nov 21;
Revsbech IG, Malte H, Fröbert O, Evans A, Blanc S, Josefsson J, Fago A

During winter hibernation, brown bears (Ursus arctos) reduce basal O(2) consumption rate to ~25% compared to the active state, whilst body temperature decreases moderately (to ~30°C), suggesting a temperature-independent component in their metabolic depression. To establish whether changes in O(2) consumption during hibernation correlate with changes in blood O(2) affinity, we took blood samples from the same six individuals of hibernating and non-hibernating free-ranging brown bears during winter and summer, respectively. A single hemoglobin (Hb) component was detected in all samples, indicating no switch in Hb synthesis. O(2) binding curves measured on red blood cell lysates at 30 and 37°C showed a less temperature-senstitive O(2) affinity than in other vertebrates. Furthermore, hemolysates from hibernating bears consistently showed lower cooperativity and higher O(2) affinity than their summer counterparts, regardless of the temperature. We found that this increase in O(2) affinity was associated with a significant decrease in the red cell Hb-cofactor 2,3-diphosphoglycerate (DPG) during hibernation to approximately half of the summer value. Experiments performed on purified Hb, to which DPG had been added to match summer and winter levels, confirmed that the low DPG content was the cause of the left-shift in the Hb-O(2) equilibrium curve during hibernation. Levels of plasma lactate indicated that glycolysis is not upregulated during hibernation and that metabolism is essentially aerobic. Calculations show that the increase in Hb-O(2) affinity and decrease in cooperativity resulting from decreased red cell DPG may be crucial in maintaining a fairly constant tissue oxygen tension during hibernation in vivo.
HubMed – depression


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