Sense and Nonsense in Metabolic Control of Reproduction.

Sense and nonsense in metabolic control of reproduction.

Filed under: Eating Disorders

Front Endocrinol (Lausanne). 2012; 3: 26
Schneider JE, Klingerman CM, Abdulhay A

An exciting synergistic interaction occurs among researchers working at the interface of reproductive biology and energy homeostasis. Reproductive biologists benefit from the theories, experimental designs, and methodologies used by experts on energy homeostasis while they bring context and meaning to the study of energy homeostasis. There is a growing recognition that identification of candidate genes for obesity is little more than meaningless reductionism unless those genes and their expression are placed in a developmental, environmental, and evolutionary context. Reproductive biology provides this context because metabolic energy is the most important factor that controls reproductive success and gonadal hormones affect energy intake, storage, and expenditure. Reproductive hormone secretion changes during development, and reproductive success is key to evolutionary adaptation, the process that most likely molded the mechanisms that control energy balance. It is likely that by viewing energy intake, storage, and expenditure in the context of reproductive success, we will gain insight into human obesity, eating disorders, diabetes, and other pathologies related to fuel homeostasis. This review emphasizes the metabolic hypothesis: a sensory system monitors the availability of oxidizable metabolic fuels and orchestrates behavioral motivation to optimize reproductive success in environments where energy availability fluctuates or is unpredictable.
HubMed – eating


Filling America’s Fiber Intake Gap: Summary of a Roundtable to Probe Realistic Solutions with a Focus on Grain-Based Foods.

Filed under: Eating Disorders

J Nutr. 2012 May 30;
Clemens R, Kranz S, Mobley AR, Nicklas TA, Raimondi MP, Rodriguez JC, Slavin JL, Warshaw H

Current fiber intakes are alarmingly low, with long-term implications for public health related to risk of coronary heart disease, stroke, hypertension, certain gastrointestinal disorders, obesity, and the continuum of metabolic dysfunctions including prediabetes and type 2 diabetes. Eating patterns high in certain fibers are known to lower LDL cholesterol and blood pressure, lower blood glucose, and decrease insulin resistance in people with prediabetes and type 2 diabetes; help with both weight loss and maintenance; and improve bowel regularity and gastrointestinal health. With >90% of adults and children who fall short of meeting their daily fiber recommendations, the 2010 Dietary Guidelines for Americans once again classified fiber as a nutrient of concern. Despite efforts over the past decade to promote adequate fiber through fruit, vegetable, and whole-grain intakes, fiber consumption has remained flat at approximately half the daily recommended amount. The public health implications of inadequate fiber intake prompted the roundtable session “Filling America’s Fiber Gap: Probing Realistic Solutions,” which assembled nutrition researchers, educators, and communicators to identify challenges, opportunities, and realistic solutions to help fill the current fiber gap. The roundtable discussions highlighted the need for both consumer and professional education to improve acceptance for and inclusion of grain-based foods with added fiber as one strategy for increasing fiber intakes within daily energy goals.
HubMed – eating


Increased medial orbitofrontal [(18) F]fluorodopa uptake in Parkinsonian impulse control disorders.

Filed under: Eating Disorders

Mov Disord. 2012 May; 27(6): 778-82
Joutsa J, Martikainen K, Niemelä S, Johansson J, Forsback S, Rinne JO, Kaasinen V

Impulse control disorders (ICDs) occur frequently in PD patients.To investigate the possible involvement of the mesostriatal and mesolimbic monoaminergic function in ICDs associated with PD, we examined patients with (n = 10) and without (n = 10) ICDs using the brain [(18) F]fluorodopa PET.Patients with ICDs (e.g., pathological gambling, hypersexuality, and compulsive eating) showed up to 35% higher [(18) F]fluorodopa uptake in the medial orbitofrontal cortex, compared to control patients, but no differences in the striatum. The results remained significant also after excluding subjects with comorbid psychiatric disorders.Increased monoaminergic activity in the medial orbitofrontal cortex might be associated with increased sensitivity for ICDs under dopamine-replacement therapy in PD. © 2012 Movement Disorder Society.
HubMed – eating


Early babies 'risk mental illness'

Filed under: Eating Disorders

Their risk of bipolar disorder is increased more than seven-fold, while the chances of developing major depression and eating disorders are raised 2.9 and 3.5 times. Experts stressed that the chances of a premature baby having a serious psychiatric …
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Eating Disorder Survivor Releases Online Eating Disorder Recovery Program

Filed under: Eating Disorders

Former eating disorder sufferer who has been recovered for almost a decade has released an online Eating Disorder Recovery Program to help those who are still suffering to recover form all eating disorders. I have experienced full recovery and freedom …
Read more on PR Web (press release)


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