Rehab Centers: Neuropathic Mechanisms in the Pathophysiology of Burns Pruritus: Redefining Directions for Therapy and Research.

Neuropathic Mechanisms in the Pathophysiology of Burns Pruritus: Redefining Directions for Therapy and Research.

Filed under: Rehab Centers

J Burn Care Res. 2012 Nov 6;
Goutos I

Pruritus in burn wounds is a common symptom affecting patient rehabilitation. Over the last decades, there has been a resurgence of interest into more effective strategies to combat this distressing problem; nevertheless, no reports exist in the literature to propose pathophysiological mechanisms responsible for the generation and persistence of pruritic symptoms in the late phases of burns rehabilitation. Neuronal pathways mediating pruritic and painful stimuli share striking similarities, which allows the comparative exploration of the less extensively studied pruritic mechanisms using pain models. Furthermore, emerging anatomical, neurophysiological, and pharmacological evidence support the involvement of neuropathic mechanisms in chronic burns pruritus. This work updates the conceptual framework for the pathophysiology of burns itch by embracing the contribution of the central nervous system in the maintenance of symptoms into a chronic state. The proposed pathophysiological model paves new avenues in burns pruritus research and is likely to have implications in the quest for more effective therapeutic regimens in clinical practice.
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Two-Dimensional Real-Time Blood Flow and Temperature of Soft Tissue Around Maxillary Anterior Implants.

Filed under: Rehab Centers

Implant Dent. 2012 Nov 6;
Nakamoto T, Kanao M, Kondo Y, Kajiwara N, Masaki C, Takahashi T, Hosokawa R

PURPOSE:: The aims of this study were to (1) evaluate the basic nature of soft tissue surrounding maxillary anterior implants by simultaneous measurements of blood flow and surface temperature and (2) analyze differences with and without bone grafting associated with implant placement to try to detect the signs of surface morphology change. MATERIALS AND METHODS:: Twenty maxillary anterior implant patients, 10 bone grafting and 10 graftless, were involved in this clinical trial. Soft tissue around the implant was evaluated with 2-dimensional laser speckle imaging and a thermograph. RESULTS:: Blood flow was significantly lower in attached gingiva surrounding implants in graftless patients (P = 0.0468). On the other hand, it was significantly lower in dental papillae (P = 0.0254), free gingiva (P = 0.0198), and attached gingiva (P = 0.00805) in bone graft patients. Temperature was significantly higher in free gingiva (P = 0.00819) and attached gingiva (P = 0.00593) in graftless patients, whereas it was significantly higher in dental papilla and free gingiva in implants with bone grafting. CONCLUSION:: The results suggest that simultaneous measurements of soft-tissue blood flow and temperature is a useful technique to evaluate the microcirculation of soft tissue surrounding implants.
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Anterior interosseous nerve involvement in a patient due to weight lifting: MRI and EMG finding.

Filed under: Rehab Centers

Neurol India. 2012 Sep-Oct; 60(5): 527-8
Koc ER, Cemeroglu O, Ayturk Z, Ilhan A

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