Estimation of the Serum and the Salivary Trace Elements in OSMF Patients.

Estimation of the Serum and the Salivary Trace Elements in OSMF Patients.

J Clin Diagn Res. 2013 Jun; 7(6): 1215-8
Kode MA, Karjodkar FR

Objectives: Gutkha packets contain trace elements like copper, zinc, iron and magnesium. This study compared the levels of the trace elements in patients with gutkha eating habits with or without oral submucous fibrosis and in healthy patients. Study Design: A total of 75 patients were included in this study and they were divided into three groups; the individuals with a history of gutkha intake with OSMF, the individuals with a history of gutkha intake without OSMF and apparently healthy individuals without OSMF and without any habits. Blood and saliva was collected and they were subjected for analysis by using atomic absorption spectrometry and a differential pulse anodic stripping voltmeter. Results: The results were tabulated and they were subjected to a statistical analysis. Conclusion: There was a significant difference in the serum Mg and Fe levels between the patients with habits and the normal healthy individuals. A significant difference was observed in the serum zinc levels in the patients with habits with and without OSMF. Altered serum trace element levels are documented in malignant cases and they are considered to be good biomarkers for malignancies. The serum copper and Zn levels and the Cu/Zn ratio in OSMF patients can be considered as the markers which show a susceptibility towards cancer. HubMed – eating

Sex differences in the physiology of eating.

Am J Physiol Regul Integr Comp Physiol. 2013 Jul 31;
Asarian L, Geary N

Hypothalamic-pituitary-gonadal (HPG) axis function fundamentally affects the physiology of eating. We review sex differences in the physiological and pathophysiological controls of amount eaten in rats, mice, monkeys and humans. These controls result from interactions among genetic effects, organizational effects of reproductive hormones (i.e., permanent early developmental effects), and activational effects of these hormones (i.e., effects dependent on hormone levels). Male-female sex differences in the physiology of eating involve both organizational and activational effects of androgens and estrogens. An activational effect of estrogens decreases eating (1) during the periovulatory period of the ovarian cycle in rats, mice, monkeys and women and (2) tonically between puberty and reproductive senescence or ovariectomy in rats and monkeys, sometimes in mice, and possibly in women. Estrogens acting on estrogen receptor-? (ER?) in the caudal medial nucleus of the solitary tract appear to mediate these effects in rats. Androgens, prolactin, and other reproductive hormones also affect eating in rats. Sex differences in eating are mediated by alterations in orosensory capacity and hedonics, gastric mechanoreception, ghrelin, CCK, GLP-1, glucagon, insulin, amylin, apolipoprotein A-IV, fatty-acid oxidation and leptin. The control of eating by central neurochemical signaling via serotonin, MSH, NPY, AgRP, MCH and dopamine are modulated by HPG function. Finally, sex differences in the physiology of eating may contribute to human obesity, anorexia nervosa, and binge eating. The variety and physiological importance of what has been learned so far warrant intensifying basic, translational and clinical research on sex differences in eating. HubMed – eating

Gender differences in food craving among overweight and obese patients attending low energy diet therapy: a matched case-control study.

Eat Weight Disord. 2013 Aug 2;
Imperatori C, Innamorati M, Tamburello S, Continisio M, Contardi A, Tamburello A, Fabbricatore M

This case-control study examined gender differences in food craving among a sample of overweight and obese patients attending low energy diet therapy. To disentangle the specific role of gender from the role of confounders, we paired groups for BMI, age and severity of binge eating as assed by the Binge Eating Scale (BES). The participants were 73 pairs of patients who were attending low energy diet therapy. All the participants were administered the State and Trait Food Cravings Questionnaire, trait version (FCQ-T) and the BES. Female patients had higher mean scores on six out of nine dimensions of the FCQ-T. When controlling for the effect of other variables, obese and overweight female patients were 1.1 times more likely to report higher anticipation of relief of negative states and feelings from eating than their male pairs. Obese and overweight female patients experience more cravings for food than their male pairs despite comparable severity of binge eating and obesity suggesting the need for tailored interventions. HubMed – eating

Risk behaviors for eating disorder in adolescents and adults with type 1 diabetes.

Rev Bras Psiquiatr. 2013 Apr; 35(2): 150-6
Philippi ST, Cardoso MG, Koritar P, Alvarenga M

Objective: To evaluate the frequency of risk behaviors for eating disorder (ED) in patients with type 1 diabetes (T1D) and their association with gender, nutritional status, variables related to T1D, and body satisfaction. Method: 189 individuals with T1D (12-56 years old) answered the Bulimic Investigation Test (BITE), the Eating Attitude Test (EAT), the Binge Eating Scale (BES), Stunkard’s Figure Rating Scale, and questions regarding control of T1D. Association between ED risk behaviors and the selected variables was assessed with the chi-square test and Student’s t-test; factors that influenced the risk of ED were identified by means of logistic regression. Results: Of the patients with T1D, 58.7% were at risk of ED (45, 40, and 16% according to the EAT, BITE and BES, respectively). There were significant differences between groups with and without risk for ED related to BMI (p = 0.009), gender (p = 0.001), insulin omission (p = 0.003), use of the carbohydrate counting method (p = 0.019), and body dissatisfaction (p = 0.001). The risk of ED was nine times higher in patients who reduced or omitted insulin (p = 0.036). Conclusions: Patients with T1D demonstrated a high frequency of body dissatisfaction and ED risk behaviors; the omission or reduction of insulin was an important risk factor. HubMed – eating

Interview Robert Spooner on Eating Disorders
CU-TV @ Mental Health Week: Interview with Robert Spooner on Eating Disorders.