Emotion Processing Bias and Age of Seizure Onset Among Epilepsy Patients With Depressive Symptoms.

Emotion processing bias and age of seizure onset among epilepsy patients with depressive symptoms.

Filed under: Depression Treatment

Epilepsy Behav. 2012 Nov 12; 25(4): 552-557
Brand JG, Mindt MR, Schaffer SG, Alper KR, Devinsky O, Barr WB

The current study examined whether mood-congruent biases in emotion processing extend to epilepsy patients with depressive symptoms and the potentially moderating effects of age of seizure onset on these biases. In addition, we examined associations between depression (Beck Depression Inventory – 2nd Edition; BDI-II) and quality of life (Quality of Life in Epilepsy – 10-item questionnaire; QOLIE-10). Data from 101 epilepsy patients were analyzed, including 61 females and 40 males. Measures included the Comprehensive Affect Testing System – Abbreviated (CATS-A), from which indices of mood-congruent bias were derived. A significant interaction between BDI-II raw scores and age of seizure onset was found for mood-congruent bias scores in the facial affect modality (?=-0.24, p<.03). Beck Depression Inventory - 2nd Edition raw scores were significantly and positively correlated with quality of life (QOLIE-10; r=.69, p<.01). Results of the current study show that epilepsy patients with an early age of seizure onset may be most at risk for mood-congruent biases when experiencing depressive symptoms and that such symptoms have real-world implications for quality of life for persons living with epilepsy. HubMed – depression


Reliability and validity of the Korean version of the Neurological Disorders Depression Inventory for Epilepsy (K-NDDI-E).

Filed under: Depression Treatment

Epilepsy Behav. 2012 Nov 12; 25(4): 539-542
Ko PW, Hwang J, Lim HW, Park SP

The Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) was developed as a screening instrument for rapid detection of major depression in people with epilepsy (PWE). We evaluated the reliability and validity of the Korean version of the NDDI-E (K-NDDI-E) in Korean PWE. This study applied to 121 outpatients who underwent psychometric tests including the Mini International Neuropsychiatric Interview-Plus Version 5.0.0, Beck Depression Inventory-II (BDI-II), and K-NDDI-E. The K-NDDI-E was easily comprehended and quickly completed by the patients. Cronbach’s ? coefficient was 0.898. At a cut off score of 11, the K-NDDI-E had a sensitivity of 84.6%, a specificity of 85.3%, a positive predictive value of 61.1%, and a negative predictive value of 95.3%. The scores of the K-NDDI-E had a positive correlation with those of the BDI-II (p<0.001). In conclusion, the K-NDDI-E is a reliable and valid screening tool to detect major depression in Korean PWE. HubMed – depression



Magnet Therapy for Depression – One in ten US adults (about 15 million Americans) report depression, a mental illness that can be debilitating for those who suffer from it. Now, a new non-invasive treatment using magnets is showing good results for patients with treatment resistant depression.


More Depression Treatment Information…